Molecular Chaperones Hsp90 and Hsp70 Deliver Preproteins to the Mitochondrial Import Receptor Tom70

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2002 • 3,280 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

Structure of TPR Domain–Peptide Complexes

2000 • 1,159 citations

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2000 • 971 citations

A mitochondrial specific stress response in mammalian cells

2002 • 907 citations

Hsp90

2001 • 819 citations

PROTEIN TRANSPORT ACROSS THE EUKARYOTIC ENDOPLASMIC RETICULUM AND BACTERIAL INNER MEMBRANES

1996 • 560 citations

BAG-1 modulates the chaperone activity of Hsp70/Hsc70

1997 • 511 citations

Versatility of the mitochondrial protein import machinery

2001 • 498 citations

Structure of a Bag/Hsc70 Complex: Convergent Functional Evolution of Hsp70 Nucleotide Exchange Factors

2001 • 427 citations

Getting Newly Synthesized Proteins into Shape

2000 • 426 citations

GrpE-like regulation of the Hsc70 chaperone by the anti-apoptotic protein BAG-1

1997 • 397 citations

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria.

1988 • 380 citations

Chaperone Function of Hsp90-Associated Proteins

1996 • 376 citations

MOM19, an import receptor for mitochondrial precursor proteins

1989 • 334 citations

A mitochondrial import receptor for the ADP/ATP carrier

1990 • 296 citations

Differential Recognition of Preproteins by the Purified Cytosolic Domains of the Mitochondrial Import Receptors Tom20, Tom22, and Tom70

1997 • 272 citations

Preprotein Translocase of the Outer Mitochondrial Membrane: Molecular Dissection and Assembly of the General Import Pore Complex

1998 • 250 citations

Distinct steps in the import of ADP/ATP carrier into mitochondria.

1987 • 248 citations

The three modules of ADP/ATP carrier cooperate in receptor recruitment and translocation into mitochondria

2001 • 243 citations

Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23

2000 • 230 citations

Ligand Discrimination by TPR Domains

2002 • 229 citations

Specific Binding of Tetratricopeptide Repeat Proteins to the C-terminal 12-kDa Domain of hsp90

1998 • 228 citations

Functional cooperation of mitochondrial protein import receptors in yeast.

1993 • 227 citations

Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange.

2001 • 220 citations

Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria.

1982 • 220 citations

Role of the ABC Transporter Mdl1 in Peptide Export from Mitochondria

2001 • 205 citations

Import of ADP/ATP carrier into mitochondria: two receptors act in parallel.

1990 • 201 citations

Transport of the ADP/ATP carrier of mitochondria from the TOM complex to the TIM2254 complex

1999 • 199 citations

Functional Staging of ADP/ATP Carrier Translocation across the Outer Mitochondrial Membrane

1999 • 180 citations

Import and assembly of proteins into mitochondria of mammalian cells

2002 • 163 citations

MSF, a novel cytoplasmic chaperone which functions in precursor targeting to mitochondria.

1994 • 144 citations

The mitochondrial import receptor Tom70: identification of a 25 kda core domain with a specific binding site for preproteins 1 1Edited by M. Yaniv

2000 • 97 citations

The cleavable presequence is not essential for import and assembly of the phosphate carrier of mammalian mitochondria but enhances the specificity and efficiency of import.

1992 • 88 citations

Prediction of Novel Bag-1 Homologs Based on Structure/Function Analysis Identifies Snl1p as an Hsp70 Co-chaperone in Saccharomyces cerevisiae

2002 • 80 citations

Characterization of rat TOM70 as a receptor of the preprotein translocase of the mitochondrial outer membrane

2002 • 72 citations

Effect of deletions within the leader peptide of pre‐ornithine transcarbamylase on mitochondrial import

1986 • 28 citations

Import of ADP/ATP carrier into mitochondria

1990 • 4 citations