Functional Staging of ADP/ATP Carrier Translocation across the Outer Mitochondrial Membrane

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Current protocols in molecular biology

1988 • 2,473 citations

Guide to Yeast Genetics and Molecular Biology

1993 • 2,377 citations

Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

1991 • 2,240 citations

Analysis of Molecular Masses and Oligomeric States of Protein Complexes by Blue Native Electrophoresis and Isolation of Membrane Protein Complexes by Two-Dimensional Native Electrophoresis

1994 • 1,211 citations

Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria.

1982 • 1,152 citations

Common Principles of Protein Translocation Across Membranes

1996 • 1,081 citations

[Protein import into mitochondria].

2000 • 971 citations

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria

1986 • 723 citations

Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins

1998 • 503 citations

Transport of proteins into mitochondria: Translocational intermediates spanning contact sites between outer and inner membranes

1985 • 470 citations

Polypeptide and phospholipid composition of the membrane of rat liver peroxisomes: comparison with endoplasmic reticulum and mitochondrial membranes.

1982 • 374 citations

MOM19, an import receptor for mitochondrial precursor proteins

1989 • 334 citations

Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22

1996 • 330 citations

Mitochondrial protein import: Nucleoside triphosphates are involved in conferring import-competence to precursors

1987 • 322 citations

Import of Mitochondrial Carriers Mediated by Essential Proteins of the Intermembrane Space

1998 • 304 citations

The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44

1997 • 302 citations

A mitochondrial import receptor for the ADP/ATP carrier

1990 • 296 citations

Tom5 functionally links mitochondrial preprotein receptors to the general import pore

1997 • 290 citations

Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5

1998 • 284 citations

Protein import into yeast mitochondria is accelerated by the outer membrane protein MAS70.

1990 • 276 citations

Successive translocation into and out of the mitochondrial matrix: Targeting of proteins to the intermembrane space by a bipartite signal peptide

1987 • 275 citations

A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site

1989 • 274 citations

A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins.

1993 • 274 citations

Differential Recognition of Preproteins by the Purified Cytosolic Domains of the Mitochondrial Import Receptors Tom20, Tom22, and Tom70

1997 • 272 citations

Identification of a mitochondrial receptor complex required for recognition and membrane insertion of precursor proteins

1990 • 267 citations

Preprotein Translocase of the Outer Mitochondrial Membrane: Molecular Dissection and Assembly of the General Import Pore Complex

1998 • 250 citations

Distinct steps in the import of ADP/ATP carrier into mitochondria.

1987 • 248 citations

Functional cooperation of mitochondrial protein import receptors in yeast.

1993 • 227 citations

The Tim54p–Tim22p Complex Mediates Insertion of Proteins into the Mitochondrial Inner Membrane

1997 • 214 citations

Translocation arrest by reversible folding of a precursor protein imported into mitochondria. A means to quantitate translocation contact sites.

1989 • 212 citations

Import of ADP/ATP carrier into mitochondria: two receptors act in parallel.

1990 • 201 citations

Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins

1998 • 200 citations

The mitochondrial receptor complex: A central role of MOM22 in mediating preprotein transfer from receptors to the general insertion pore

1993 • 194 citations

Mapping of the protein import machinery in the mitochondrial outer membrane by crosslinking of translocation intermediates

1992 • 185 citations

Tom7 modulates the dynamics of the mitochondrial outer membrane translocase and plays a pathway-related role in protein import.

1996 • 180 citations

Interaction of mitochondrial targeting signals with acidic receptor domains along the protein import pathway: evidence for the 'acid chain' hypothesis

1998 • 178 citations

Mas37p, a novel receptor subunit for protein import into mitochondria.

1995 • 176 citations

Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. Isolation and analysis of AAC2.

1988 • 173 citations

Reconstitution of the initial steps of mitochondrial protein import

1995 • 172 citations

Transport of Proteins into Mitochondria. Posttranslational Transfer of ADP/ATP Carrier into Mitochondria in vitro

1980 • 167 citations

MITOCHONDRIAL PREPROTEIN TRANSLOCASE

1997 • 163 citations

Import pathways of precursor proteins into mitochondria: multiple receptor sites are followed by a common membrane insertion site.

1988 • 159 citations

The mitochondrial outer membrane protein Mas22p is essential for protein import and viability of yeast.

1994 • 157 citations

The protein import receptor of mitochondria

1995 • 153 citations

MOM22 is a receptor for mitochondrial targeting sequences and cooperates with MOM19.

1995 • 145 citations

Tim9, a new component of the TIM2254 translocase in mitochondria

1999 • 143 citations

Mitochondrial biogenesis: The Tom and Tim machine

1997 • 134 citations

The Mitochondrial Receptor Complex: Mom22 Is Essential for Cell Viability and Directly Interacts with Preproteins†

1995 • 132 citations

Protein translocation across mitochondrial membranes: What a long, strange trip it is

1995 • 129 citations

Deletion of the receptor MOM19 strongly impairs import of cleavable preproteins into Saccharomyces cerevisiae mitochondria.

1994 • 124 citations

Binding of mitochondrial precursor proteins to the cytoplasmic domains of the import receptors Tom70 and Tom20 is determined by cytoplasmic chaperones

1997 • 119 citations

Chapter 16 Analysis of Mitochondrial Protein Import Using Translocation Intermediates and Specific Antibodies

1991 • 115 citations

Antibodies against synthetic peptides as a tool for functional analysis of the transforming protein pp60src

1983 • 103 citations

Dynamic interaction of the protein translocation systems in the inner and outer membranes of yeast mitochondria.

1995 • 95 citations

Mitochondrial preproteins en route from the outer membrane to the inner membrane are exposed to the intermembrane space

1991 • 90 citations

Insertion of MOM22 into the mitochondrial outer membrane strictly depends on surface receptors

1993 • 79 citations

Characterization of the preprotein translocase of the outer mitochondrial membrane by blue native electrophoresis.

1996 • 73 citations

‘Sheltered disruption’ of Neurospora crassa MOM22, an essential component of the mitochondrial protein import complex.

1995 • 71 citations

[15] Pathways and energetics of mitochondrial protein import in Saccharomyces cerevisiae

1995 • 64 citations

The protein import receptor MOM19 of yeast mitochondria

1993 • 61 citations

Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane

1998 • 60 citations

Mitochondrial import: Crossing the aqueous intermembrane space

1998 • 60 citations

Functional and Physical Interactions of Components of the Yeast Mitochondrial Inner‐Membrane Import Machinery (MIM)

1995 • 58 citations

[19] Mitochondrial receptor complex from Neurospora crassa and Saccharomyces cerevisiae

1995 • 48 citations

The Import Route of ADP/ATP Carrier into Mitochondria Separates from the General Import Pathway of Cleavable Preproteins at thetrans Side of the Outer Membrane

1998 • 45 citations

Transport of ADP/ATP carrier into mitochondria. Precursor imported in vitro acquires functional properties of the mature protein.

1984 • 39 citations