Immunophenotyping of acute leukemias and myelodysplastic syndromes

Proposals for the Classification of the Acute Leukaemias F<scp>rench</scp>‐A<scp>merican</scp>‐B<scp>ritish</scp> (FAB) C<scp>o‐operative</scp> G<scp>roup</scp>

1976 • 5,620 citations

International Scoring System for Evaluating Prognosis in Myelodysplastic Syndromes

1997 • 4,416 citations

Proposals for the classification of the myelodysplastic syndromes

1982 • 3,616 citations

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

The World Health Organization (WHO) classification of the myeloid neoplasms

2002 • 2,168 citations

Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage

1980 • 1,668 citations

Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL).

1995 • 1,374 citations

Criteria for the Diagnosis of Acute Leukemia of Megakaryocyte Lineage (M7)

1985 • 752 citations

Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML‐MO)

1991 • 686 citations

Proposals for immunological classification of acute leukemias.

1995 • 543 citations

Flow cytometric analysis of human bone marrow. II. Normal B lymphocyte development

1987 • 451 citations

Clinical and biologic features of CD4+CD56+ malignancies

2002 • 420 citations

Flow cytometric analysis of human bone marrow: I. Normal erythroid development

1987 • 353 citations

Myeloid and monocytic dyspoiesis as determined by flow cytometric scoring in myelodysplastic syndrome correlates with the IPSS and with outcome after hematopoietic stem cell transplantation

2003 • 350 citations

Early immunophenotypical evaluation of minimal residual disease in acute myeloid leukemia identifies different patient risk groups and may contribute to postinduction treatment stratification

2001 • 334 citations

Diagnostic utility of flow cytometric immunophenotyping in myelodysplastic syndrome

2001 • 292 citations

Immunophenotyping Investigation of Minimal Residual Disease Is a Useful Approach for Predicting Relapse in Acute Myeloid Leukemia Patients

1997 • 271 citations

ACUTE LYMPHOBLASTIC LEUKÆMIA IN CHILDREN: CLASSIFICATION AND PROGNOSIS

1977 • 256 citations

Level of minimal residual disease after consolidation therapy predicts outcome in acute myeloid leukemia

2000 • 245 citations

Minimal residual disease in leukaemia patients

2001 • 243 citations

Terminal Transferase-Positive Human Bone Marrow Cells Exhibit the Antigenic Phenotype of Common Acute Lymphoblastic Leukemia

1979 • 243 citations

Patterns of gene expression and the cellular origins of human leukaemias

1978 • 242 citations

Flow cytometric analysis of normal B cell differentiation: a frame of reference for the detection of minimal residual disease in precursor-B-ALL

1999 • 237 citations

Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin)

2002 • 224 citations

Level of minimal residual disease after consolidation therapy predicts outcome in acute myeloid leukemia

2000 • 206 citations

Phenotypic heterogeneity and cellular origins of T cell malignancies

1981 • 200 citations

Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia

2002 • 199 citations

Flow cytometric analysis of human bone marrow. III. Neutrophil maturation.

1990 • 197 citations

Distinctive immunophenotypic features of t(8;21)(q22;q22) acute myeloblastic leukemia in children [see comments]

1992 • 194 citations

Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia

2002 • 189 citations

The Reliability and Specificity of c-kit for the Diagnosis of Acute Myeloid Leukemias and Undifferentiated Leukemias

1998 • 187 citations

Outcome of biphenotypic acute leukemia.

1999 • 177 citations

Flow cytometric characterization of acute myeloid leukemia. Part II. Phenotypic heterogeneity at diagnosis.

1992 • 170 citations

Characterization of childhood acute leukemia with multiple myeloid and lymphoid markers at diagnosis and at relapse [see comments]

1991 • 169 citations

Cellular phenotypes of normal and leukemic hemopoietic cells determined by analysis with selected antibody combinations

1980 • 167 citations

Asynchronous antigen expression in B lineage acute lymphoblastic leukemia

1988 • 165 citations

Terminal Transferase Enzyme Assay and Immunological Membrane Markers in the Diagnosis of Leukaemia: a Multiparameter Analysis of 300 Cases

1980 • 154 citations

Determination of minimal residual disease in leukaemia patients

2003 • 154 citations

Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia

2001 • 149 citations

Flow cytometry in the diagnosis of acute leukemia

2001 • 148 citations

Immunophenotypic analysis of mast cells in mastocytosis: When and how to do it. Proposals of the Spanish Network on Mastocytosis (REMA)

2004 • 142 citations

BIOMED-1 concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainings

2001 • 140 citations

Myeloid cell differentiation in normal bone marrow and acute myeloid leukemia assessed by multi-dimensional flow cytometry.

1990 • 139 citations

Minimal residual disease in adolescent (older than 14 years) and adult acute lymphoblastic leukemias: early immunophenotypic evaluation has high clinical value

2003 • 134 citations

EXPRESSION OF HUMAN T AND B LYMPHOCYTE CELL-SURFACE MARKERS ON LEUKÆMIC CELLS

1974 • 134 citations

Predictability of the t(1;19)(q23;p13) from surface antigen phenotype: implications for screening cases of childhood acute lymphoblastic leukemia for molecular analysis: a Pediatric Oncology Group study

1993 • 128 citations

The flow cytometric pattern of CD34, CD15 and CD13 expression in acute myeloblastic leukemia is highly characteristic of the presence of PML-RARalpha gene rearrangements.

1999 • 126 citations

Revised guideline on immunophenotyping in acute leukaemias and chronic lymphoproliferative disorders

2002 • 124 citations

Immunophenotypic clustering of myelodysplastic syndromes

2002 • 122 citations

Clinically useful information provided by the flow cytometric immunophenotyping of hematological malignancies: current status and future directions.

1999 • 122 citations

Incidence and characteristics of CD4(+)/HLA DRhi dendritic cell malignancies.

2004 • 116 citations

Leukemias with megakaryoblastic involvement: clinical, hematologic, and immunologic characteristics

1988 • 114 citations

BIOMED-1 Concerted Action report: Flow cytometric characterization of CD7+ cell subsets in normal bone marrow as a basis for the diagnosis and follow-up of T cell acute lymphoblastic leukemia (T-ALL)

2000 • 113 citations

Adult precursor B-ALL with BCR/ABL gene rearrangements displays a unique immunophenotype based on the pattern of CD10, CD34, CD13 and CD38 expression

2001 • 111 citations

Surface marker analysis in acute myeloid leukaemia and correlation with FAB classification

1986 • 111 citations

Quantitative Comparison of Myeloid Antigens on Five Lineages of Mature Peripheral Blood Cells

1990 • 111 citations

Characterization of childhood acute leukemia with multiple myeloid and lymphoid markers at diagnosis and at relapse [see comments]

1991 • 110 citations

Acute myeloid leukemia with MLL rearrangements: clinicobiological features, prognostic impact and value of flow cytometry in the detection of residual leukemic cells

2003 • 107 citations

Correlation of karyotype and immunophenotype in childhood acute lymphoblastic leukemia.

1988 • 105 citations

Clinical applications of laser scanning cytometry

2002 • 102 citations

Acute lymphoblastic leukemia with the (8;14)(q24;q32) translocation and FAB L3 morphology associated with a B-precursor immunophenotype: the Pediatric Oncology Group experience

1999 • 98 citations

Immunological classification of acute myeloblastic leukemias: relevance to patient outcome

2003 • 96 citations

Comparative Analysis of the Morphological, Cytochemical, Immunophenotypical, and Functional Characteristics of Normal Human Peripheral Blood Lineage−/CD16+/HLA-DR+/CD14−/lo Cells, CD14+ Monocytes, and CD16− Dendritic Cells

2001 • 92 citations

Four-Color Flow Cytometric Investigation of Terminal Deoxynucleotidyl Transferase–Positive Lymphoid Precursors in Pediatric Bone Marrow: CD79a Expression Precedes CD19 in Early B-Cell Ontogeny

1998 • 91 citations

Quantitative multiparametric immunophenotyping in acute lymphoblastic leukemia: correlation with specific genotype. I. ETV6/AML1 ALLs identification

2000 • 88 citations

Characterization of aberrant phenotypes in acute myeloblastic leukemia

1995 • 87 citations

Surface antigen phenotype can predict TEL-AML1 rearrangement in childhood B-precursor ALL: a Pediatric Oncology Group study

1998 • 86 citations

Detection of minimal residual disease in unselected patients with acute myeloid leukemia using multiparameter flow cytometry for definition of leukemia-associated immunophenotypes and determination of their frequencies in normal bone marrow.

2003 • 86 citations

Inhibition of in vitro spontaneous apoptosis by IL-7 correlates with Bcl-2 up-regulation, cortical/mature immunophenotype, and better early cytoreduction of childhood T-cell acute lymphoblastic leukemia

2000 • 86 citations

Detection of acute leukemia cells with mixed lineage leukemia (MLL) gene rearrangements by flow cytometry using monoclonal antibody 7.1

2000 • 84 citations

Acute myeloid leukemia with 11q23 translocations: myelomonocytic immunophenotype by multiparameter flow cytometry

1998 • 80 citations

Immunological detection of blast cell subpopulations in acute myeloblastic leukemia at diagnosis: implications for minimal residual disease studies.

1995 • 77 citations

Surface marker abnormalities in myelodysplastic syndromes.

1998 • 75 citations

Impact of immunophenotyping on management of acute leukemias.

1999 • 71 citations

Myelodysplastic syndrome: a search for minimal diagnostic criteria

1999 • 67 citations

Flow Cytometric Analysis of Cerebrospinal Fluid Samples and Its Usefulness in Routine Clinical Practice

2002 • 64 citations

Acute leukemia after a primary myelodysplastic syndrome: immunophenotypic, genotypic, and clinical characteristics [see comments]

1991 • 63 citations

Immunophenotypic analysis of myelodysplastic syndromes.

2003 • 59 citations

Acute leukemia after a primary myelodysplastic syndrome: immunophenotypic, genotypic, and clinical characteristics [see comments]

1991 • 55 citations

Detection of abnormalities in B‐cell differentiation pattern is a useful tool to predict relapse in precursor‐B‐ALL

1999 • 53 citations

B-cell development and maturation.

1998 • 43 citations

Immunophenotypic findings in acute myeloid leukemia with FLT3 internal tandem duplication.

2003 • 43 citations

Multimarker phenotypic characterization of adult and childhood acute lymphoblastic leukaemia: an Italian multicentre study

1985 • 35 citations

Monoclonal antibody therapies in leukemias

2002 • 32 citations

Sequential analysis of CD34+ and CD34− cell subsets in peripheral blood and leukapheresis products from breast cancer patients mobilized with SCF plus G-CSF and cyclophosphamide

2001 • 28 citations

Membrane Marker Analysis of ‘Lymphoid’ and Myeloid Blast Crisis in PH1 Positive (Chronic Myeloid) Leukemia

1977 • 22 citations

Immunophenotypic characteristics of PB-mobilised CD34+ hematopoietic progenitor cells.

2001 • 20 citations

Immunologic monitoring in adults with acute lymphoblastic leukemia

2003 • 11 citations

Aplicación de la citometría de flujo al diagnóstico y seguimiento inmunofenotípico de las leucemias agudas

2002 • 11 citations

Between the idea and the reality falls the shadow: Clinical flow cytometry comes of age?

1988 • 5 citations

Inhibition of in vitro spontaneous apoptosis by IL-7 correlates with Bcl-2 up-regulation, cortical/mature immunophenotype, and better early cytoreduction of childhood T-cell acute lymphoblastic leukemia

2000 • 5 citations

Immunophenotype of Hematologic Neoplasms with a Translocation t(8;21)

1993 • 2 citations

Deleted Work

1955 • 0 citations