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Monoclonal antibody therapies in leukemias

Data up to Jan 2025

Published2002
Citations32
References34

Total Citations Per Year

Abstract

References (34)

Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.

1998 • 2,777 citations

Efficacy and Safety of Gemtuzumab Ozogamicin in Patients With CD33-Positive Acute Myeloid Leukemia in First Relapse

2001 • 877 citations

Cytokine-Release Syndrome in Patients With B-Cell Chronic Lymphocytic Leukemia and High Lymphocyte Counts After Treatment With an Anti-CD20 Monoclonal Antibody (Rituximab, IDEC-C2B8)

1999 • 653 citations

IDEC-C2B8: results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma.

1997 • 638 citations

Rituximab Dose-Escalation Trial in Chronic Lymphocytic Leukemia

2001 • 603 citations

Calicheamicin γ 1 I : an Antitumor Antibiotic That Cleaves Double-Stranded DNA Site Specifically

1988 • 548 citations

Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia.

1997 • 531 citations

Rituximab Using A Thrice Weekly Dosing Schedule in B-Cell Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma Demonstrates Clinical Activity and Acceptable Toxicity

2001 • 521 citations

Efficacy of the Anti-CD22 Recombinant Immunotoxin BL22 in Chemotherapy-Resistant Hairy-Cell Leukemia

2001 • 514 citations

Fludarabine: a new agent with major activity against chronic lymphocytic leukemia

1989 • 466 citations

A monoclonal antibody reactive with normal and leukemic human myeloid progenitor cells

1984 • 420 citations

Rituximab therapy of patients with B-cell chronic lymphocytic leukemia

2001 • 354 citations

Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells

2001 • 332 citations

High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H

2001 • 309 citations

Mylotarg? (gemtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation

2001 • 278 citations

Fludarabine: a new agent with major activity against chronic lymphocytic leukemia

1989 • 260 citations

Fludarabine: a new agent with marked cytoreductive activity in untreated chronic lymphocytic leukemia.

1991 • 255 citations

Hepatic sinusoidal obstruction after gemtuzumab ozogamicin (Mylotarg) therapy

2002 • 240 citations

Humanized CD52 monoclonal antibody campath‐1H as first‐line treatment in chronic lymphocytic leukaemia

1996 • 239 citations

Expression of normal myeloid-associated antigens by acute leukemia cells

1986 • 227 citations

A phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy

1993 • 221 citations

Immunotoxins in cancer therapy

1999 • 214 citations

Treatment of T-cell prolymphocytic leukemia with human CD52 antibody.

1997 • 210 citations

A phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy

1993 • 185 citations

Diagnostic application of two-color flow cytometry in 161 cases of hairy cell leukemia

1993 • 181 citations

Monoclonal antibody therapy of cancer.

1999 • 96 citations

Cytotoxic activity of disulfide-stabilized recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) toward fresh malignant cells from patients with B-cell leukemias.

2000 • 88 citations

Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys

1999 • 87 citations

Hepatic venoocclusive disease in autologous bone marrow transplantation of solid tumors and lymphomas.

1990 • 72 citations

Principles of radioimmunotherapy for hematologists and oncologists.

2000 • 63 citations

Heterogeneity and Clinical Relevance of the Intensity of CD20 and Immunoglobulin Light-Chain Expression in B-Cell Chronic Lymphocytic Leukemia

1996 • 40 citations

Diagnostic relevance of peripheral blood immunocytochemistry in hairy cell leukaemia.

1995 • 24 citations

Preliminary report of the safety and efficacy of gemtuzumab ozogamicin (Mylotarg (R)) given in combination with cytarabine and daunorubicin in patients with acute myeloid leukemia

2001 • 16 citations

Deleted Work

1955 • 0 citations

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Monoclonal antibody therapies in leukemias (2002) – Seminars in Hematology | Metascience Observatory Explorer