Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing.

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

1987 • 609 citations

Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II

1987 • 394 citations

The presence of nucleosomes on a DNA template prevents initiation by RNA polymerase II in vitro

1986 • 339 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

Change in the pattern of histone binding to DNA upon transcriptional activation

1989 • 246 citations

Chromatin assembly in Xenopus oocytes: In vitro studies

1984 • 230 citations

Transcription elongation and eukaryotic gene regulation.

1990 • 227 citations

Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates.

1984 • 202 citations

Transcription Elongation Factor SII (TFIIS) Enables RNA Polymerase II to Elongate through a Block to Transcription in a Human Gene in Vitro

1989 • 189 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Transcription factor IIS stimulates elongation of RNA chains.

1987 • 160 citations

A bacteriophage RNA polymerase transcribes in vitro through a nucleosome core without displacing it

1987 • 148 citations

RNA chain elongation by Escherichia coli RNA polymerase

1990 • 139 citations

Transcription initiation by RNA polymerase II in vitro. Properties of preinitiation, initiation, and elongation complexes.

1987 • 132 citations

Nucleosomes inhibit both transcriptional initiation and elongation by RNA polymerase III in vitro.

1989 • 115 citations

Analysis of the signals for transcription termination by purified RNA polymerase II

1990 • 113 citations

Presence of histone H1 on an active Balbiani ring gene

1990 • 101 citations

The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles.

1990 • 96 citations

Purification and functional characterization of transcription factor SII from calf thymus. Role in RNA polymerase II elongation.

1987 • 96 citations

Initiation of transcription on nucleosomal templates.

1989 • 87 citations

RNA Polymerase II Transcription Blocked by Escherichia coli Lac Repressor

1990 • 86 citations

A CCAAT box sequence in the adenovirus major late promoter functions as part of an RNA polymerase II termination signal

1989 • 83 citations

Transcription of adenovirus 2 major late and peptide IX genes under conditions of in vitro nucleosome assembly.

1987 • 83 citations

Transcription initiation by RNA polymerase II in vitro. At least two nucleotides must be added to form a stable ternary complex.

1987 • 79 citations

Reversible and irreversible changes in nucleosome structure along the c-fos and c-myc oncogenes following inhibition of transcription

1990 • 74 citations

RNA polymerase II is capable of pausing and prematurely terminating transcription at a precise location in vivo and in vitro.

1989 • 69 citations

Assembly of RNA polymerase II preinitiation complexes before assembly of nucleosomes allows efficient initiation of transcription on nucleosomal templates.

1988 • 59 citations

In situ nucleoprotein structure at the SV40 major late promoter: melted and wrapped DNA flank the start site.

1989 • 58 citations

Elongation by Drosophila RNA polymerase II. Transcription of 3′-extended DNA templates.

1988 • 55 citations

In vitro evidence that transcription-induced stress causes nucleosome dissolution and regeneration.

1990 • 54 citations

Effect of transcription of yeast chromatin on DNA topology in vivo.

1990 • 53 citations

Transcription factor requirements for in vitro formation of transcriptionally competent 5S rRNA gene chromatin.

1990 • 51 citations

Purification and characterization of ternary complexes containing accurately initiated RNA polymerase II and less than 20 nucleotides of RNA

1984 • 30 citations

[13] Digestion of nucleosomes with deoxyribonucleases I and II

1989 • 19 citations