The type 1 human immunodeficiency virus Tat binding protein is a transcriptional activator belonging to an additional family of evolutionarily conserved genes.

Experiments in molecular genetics

1972 • 28,260 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

Getting started with yeast

2002 • 3,496 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

[1] Getting started with yeast

1991 • 2,456 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

Transcriptional repression by YY1, a human GLI-Krüippel-related protein, and relief of repression by adenovirus E1A protein

1991 • 1,023 citations

Trans -Activator Gene of Human T-Lymphotropic Virus Type III (HTLV-III)

1985 • 872 citations

Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.

1988 • 830 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1985 • 825 citations

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

1987 • 672 citations

The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

1986 • 615 citations

A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

1989 • 570 citations

Location of the Trans -Activating Region on the Genome of Human T-Cell Lymphotropic Virus Type III

1985 • 558 citations

A vector for expressing GAL4(1–147) fusions tn mammalian cells

1989 • 558 citations

HIV-1 tat trans-activation requires the loop sequence within tar

1988 • 551 citations

[35] Epitope tagging and protein surveillance

1991 • 526 citations

D‐E‐A‐D protein family of putative RNA helicases

1992 • 516 citations

A family of yeast expression vectors containing the phage f1 intergenic region1

1987 • 514 citations

Fragments of the HIV-1 Tat Protein Specifically Biand TAR RNA

1990 • 446 citations

Structural and functional characterization of human immunodeficiency virus tat protein

1989 • 444 citations

Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm

1989 • 417 citations

A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activation.

1990 • 412 citations

A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s)

1992 • 378 citations

GAL4 activates gene expression in mammalian cells

1988 • 355 citations

PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPases

1991 • 344 citations

HIV-1 Tat protein trans-activates transcription in vitro

1990 • 277 citations

Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulation.

1989 • 275 citations

Structural arrangements of transcription control domains within the 5'-untranslated leader regions of the HIV-1 and HIV-2 promoters.

1988 • 271 citations

A cDNA for a Protein That Interacts with the Human Immunodeficiency Virus Tat Transactivator

1990 • 234 citations

trans activation of human immunodeficiency virus type 1 is sequence specific for both the single-stranded bulge and loop of the trans-acting-responsive hairpin: a quantitative analysis

1989 • 224 citations

Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product.

1988 • 220 citations

The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: implications for Tat function.

1991 • 217 citations

Identification and characterization of a HeLa nuclear protein that specifically binds to the trans-activation-response (TAR) element of human immunodeficiency virus.

1990 • 217 citations

Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4

1992 • 196 citations

HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors.

1992 • 195 citations

Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro.

1989 • 187 citations

Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative.

1992 • 177 citations

New human gene encoding a positive modulator of HIV Tat-mediated transactivation

1992 • 163 citations

Nondissociation of GAL4 and GAL80 in Vivo After Galactose Induction

1992 • 139 citations

Use of a cDNA clone to identify a supposed precursor protein containing valosin

1987 • 134 citations

Identification of cellular proteins that bind to the human immunodeficiency virus type 1 trans-activation-responsive TAR element RNA.

1989 • 129 citations

Specific binding of a HeLa cell nuclear protein to RNA sequences in the human immunodeficiency virus transactivating region.

1989 • 121 citations

Transactivation and transformation by Myb are negatively regulated by a leucine-zipper structure.

1992 • 117 citations

Synergy between HIV-1 Tat and adenovirus E1A is principally due to stabilization of transcriptional elongation.

1990 • 114 citations

SGV1 encodes a CDC28/cdc2-related kinase required for a Gα subunit-mediated adaptive response to pheromone in S. cerevisiae

1991 • 79 citations

Characterization of a Component of the Yeast Secretion Machinery: Identification of the SEC18 Gene Product

1988 • 79 citations

Activation of Yeast Polymerase II Transcription by Herpesvirus VP16 and GAL4 Derivatives In Vitro

1989 • 56 citations

Functional Characterization of the NF-κB p65 Transcriptional Activator and an Alternatively Spliced Derivative

1992 • 49 citations

Isolation of a Yeast Gene Encoding a Protein Homologous to the Human Tat-Binding Protein TBP-1

1992 • 26 citations