A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

Binding of soluble form of fibroblast surface protein, fibronectin, to collagen

1977 • 1,972 citations

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes

1990 • 1,592 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

1980 • 903 citations

Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells

1990 • 802 citations

Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system.

1987 • 802 citations

Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes

1991 • 771 citations

Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA

1982 • 764 citations

Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

1990 • 746 citations

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization.

1989 • 627 citations

Amino acid sequence of the human fibronectin receptor.

1987 • 596 citations

Identification of a murine Peyer's patch—specific lymphocyte homing receptor as an integrin molecule with an α chain homologous to human VLA-4α

1989 • 495 citations

A β ₃ Integrin Mutation Abolishes Ligand Binding and Alters Divalent Cation-Dependent Conformation

1990 • 418 citations

Localization of an Arg-Gly-Asp Recognition Site Within an Integrin Adhesion Receptor

1988 • 402 citations

Site-directed mutagenesis of the cell-binding domain of human fibronectin: Separable, synergistic sites mediate adhesive function

1988 • 372 citations

Amplification and expression of sequences cotransfected with a modular dihydrofolate reductase complementary DNA gene

1982 • 356 citations

A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

1989 • 352 citations

The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

1989 • 343 citations

Characterization of the cell surface heterodimer VLA-4 and related peptides.

1987 • 340 citations

Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.

1981 • 303 citations

Discrimination Between Intracellular Uptake and Surface Adhesion of Bacterial Pathogens

1991 • 302 citations

Regulation of fibronectin receptor distribution [published erratum appears in J Cell Biol 1992 Jul;118(2):491]

1992 • 295 citations

The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.

1989 • 264 citations

Fibronectin and vitronectin regulate the organization of their respective Arg-Gly-Asp adhesion receptors in cultured human endothelial cells.

1988 • 256 citations

Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein.

1990 • 242 citations

The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit.

1988 • 238 citations

The lethal myospheroid gene of Drosophila encodes a membrane protein homologous to vertebrate integrin beta subunits.

1988 • 235 citations

Rapid and Efficient Site-Specific Mutagenesis without Phenotypic Selection

1989 • 233 citations

Selective Inhibition of Fibronectin-Mediated Cell Adhesion by Monoclonal Antibodies to a Cell-Surface Glycoprotein

1985 • 217 citations

Expression of normal and mutant avian integrin subunits in rodent cells [published erratum appears in J Cell Biol 1989 Oct;109(4 Pt 1):1187]

1989 • 181 citations

The cell attachment domain of fibronectin. Determination of the primary structure.

1982 • 177 citations

Inhibition of PDGF β Receptor Signal Transduction by Coexpression of a Truncated Receptor

1991 • 173 citations

The very late antigen family of heterodimers is part of a superfamily of molecules involved in adhesion and embryogenesis.

1987 • 164 citations

The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the alpha 5 beta 1 integrin receptor.

1991 • 136 citations

Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen.

1991 • 135 citations

Isolation and characterization of Chinese hamster ovary cell variants deficient in the expression of fibronectin receptor.

1989 • 135 citations

Expression of the Mouse Dihydrofolate Reductase Complementary Deoxyribonucleic Acid in Simian Virus 40 Vectors

1981 • 96 citations

Identification and quantitation of platelet-associated fibronectin antigen.

1979 • 95 citations

The M_r 140,000 fibronectin receptor complex in normal and virus‐transformed human fibroblasts and in fibrosarcoma cells: Identical localization and function

1989 • 79 citations

Monoclonal antibodies to distinctive epitopes on the α and β subunits of the fibronectin receptor

1988 • 54 citations

Fine specificity and antigen receptor expression among influenza virus-specific cytolytic T lymphocyte clones.

1986 • 30 citations