Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

A dot-immunobinding assay for monoclonal and other antibodies

1982 • 2,219 citations

FIBRONECTIN AND ITS RECEPTORS

1988 • 1,336 citations

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

1986 • 1,206 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1986 • 1,100 citations

Cell biology of extracellular matrix

1992 • 1,042 citations

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

1980 • 903 citations

Cell Surface Receptors for Extracellular Matrix Molecules

1987 • 793 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Direct Cloning and Sequence Analysis of Enzymatically Amplified Genomic Sequences

1986 • 766 citations

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro.

1975 • 747 citations

Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits.

1987 • 727 citations

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

1989 • 672 citations

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization.

1989 • 627 citations

Amino acid sequence of the human fibronectin receptor.

1987 • 596 citations

Changes in integrin receptors on oncogenically transformed cells

1989 • 548 citations

Morphological Transformation of Chinese Hamster Cells by Dibutyryl Adenosine Cyclic 3′:5′-Monophosphate and Testosterone

1971 • 529 citations

The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa.

1988 • 446 citations

Regulation of the fibronectin receptor affinity by divalent cations.

1988 • 441 citations

Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos.

1984 • 429 citations

Fibronectin in early avian embryos: Synthesis and distribution along the migration pathways of neural crest cells

1980 • 417 citations

Neural crest cell migration: requirements for exogenous fibronectin and high cell density.

1983 • 388 citations

Amplification and expression of sequences cotransfected with a modular dihydrofolate reductase complementary DNA gene

1982 • 356 citations

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.

1986 • 355 citations

Interaction of the 70,000-mol-wt amino-terminal fragment of fibronectin with the matrix-assembly receptor of fibroblasts.

1985 • 335 citations

Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion.

1985 • 322 citations

Laminin and fibronectin promote the haptotactic migration of B16 mouse melanoma cells in vitro.

1984 • 314 citations

Cell adhesion and migration in the early vertebrate embryo: location and possible role of the putative fibronectin receptor complex

1986 • 309 citations

Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.

1981 • 303 citations

Effects of LETS glycoprotein on cell motility

1978 • 277 citations

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

1989 • 272 citations

Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts.

1989 • 256 citations

Fibronectin's cell-adhesive domain and an amino-terminal matrix assembly domain participate in its assembly into fibroblast pericellular matrix.

1987 • 255 citations

Extracellular Matrix Assembly

1988 • 250 citations

Fibronectin and Its Relation to Cellular Structure and Behavior

1981 • 223 citations

Tumor Formation Dependent on Proteoglycan Biosynthesis

1988 • 217 citations

Type VI collagen. Studies on its localization, structure, and biosynthetic form with monoclonal antibodies.

1984 • 206 citations

Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures.

1988 • 186 citations

On-line detection of nitric oxide formation in liquid aqueous phase by electron paramagnetic resonance spectroscopy

1991 • 173 citations

Subunit structure of a laminin-binding integrin and localization of its binding site on laminin

1989 • 172 citations

Fibronectin has a dual role in locomotion and anchorage of primary chick fibroblasts and can promote entry into the division cycle.

1982 • 168 citations

Fibronectin promotes rat Schwann cell growth and motility.

1982 • 164 citations

Concomitant loss of cell surface fibronectin and laminin from transformed rat kidney cells

1981 • 162 citations

Integrin heterodimer and receptor complexity in avian and mammalian cells.

1989 • 156 citations

Primordial germ cells of Xenopus embryos: The role of fibronectin in their adhesion during migration

1981 • 152 citations

The fibronectin receptor is organized by extracellular matrix fibronectin: implications for oncogenic transformation and for cell recognition of fibronectin matrices.

1989 • 150 citations

Fibronectin-degrading proteases from the membranes of transformed cells

1987 • 134 citations

Cellular fibronectin promotes adrenergic differentiation of quail neural crest cells in vitro

1981 • 132 citations

Regulation of fibronectin receptor distribution by transformation, exogenous fibronectin, and synthetic peptides.

1986 • 128 citations

Fibronectin-plasma membrane interaction in the adhesion of hemopoietic cells.

1986 • 115 citations

The extracellular matrix of normal chick embryo fibroblasts: its effect on transformed chick fibroblasts and its proteolytic degradation by the transformants.

1985 • 114 citations

Laminin from rat yolk sac tumor: Isolation, partial characterization, and comparison with mouse laminin

1983 • 109 citations

Fibronectin's amino-terminal matrix assembly site is located within the 29-kDa amino-terminal domain containing five type I repeats.

1988 • 108 citations

Molecular cloning of a murine fibronectin receptor and its expression during inflammation. Expression of VLA-5 is increased in activated peritoneal macrophages in a manner discordant from major histocompatibility complex class II.

1989 • 95 citations

A 135000 molecular weight plasma membrane glycoprotein involved in fibronectin-mediated cell adhesion

1986 • 79 citations

Control of cell locomotion: perturbation with an antibody directed against specific glycoproteins

1985 • 55 citations

Increased contractile strength and tightened adhesions to the substratum result from reverse transformation of cho cells by dibutyryl cyclic adenosine monophosphate

1983 • 45 citations

Role of fibronectin in primary mesenchyme cell migration in the sea urchin.

1985 • 44 citations

Platelets express a membrane protein complex immunologically related to the fibroblast fibronectin receptor and distinct from GPIIb/IIIa

1987 • 35 citations

Basement membrane heparan sulfate proteoglycan from the L2 rat yolk sac carcinoma

1984 • 24 citations

An inhibitor of animal cell growth increases cell-to-cell adhesion.

1981 • 18 citations

Deleted Work

1955 • 0 citations