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A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

Data up to Jan 2025

Published1989
Citations352
References36

Total Citations Per Year

Abstract

References (36)

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1983 • 888 citations

Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits.

1987 • 727 citations

Laminin receptor on platelets is the integrin VLA-6

1988 • 679 citations

Amino acid sequence of the human fibronectin receptor.

1987 • 596 citations

The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets.

1985 • 594 citations

Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor.

1987 • 574 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin.

1985 • 517 citations

The cell substrate attachment (CSAT) antigen has properties of a receptor for laminin and fibronectin.

1985 • 503 citations

Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to “integrin”.

1987 • 466 citations

A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.

1989 • 314 citations

Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets.

1982 • 261 citations

Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor, and thrombospondin on thrombin-stimulated human platelets

1985 • 253 citations

An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in an divalent cation-dependent functional complex with the disialoganglioside GD2.

1987 • 246 citations

The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit.

1988 • 238 citations

cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors.

1986 • 231 citations

Tenascin mediates cell attachment through an RGD-dependent receptor.

1989 • 231 citations

Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs.

1987 • 223 citations

Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures.

1988 • 186 citations

Platelet glycoprotein IIb-IIIa-like proteins mediate endothelial cell attachment to adhesive proteins and the extracellular matrix.

1987 • 185 citations

Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3

1985 • 175 citations

Reconstitution of the purified platelet fibrinogen receptor. Fibrinogen binding properties of the glycoprotein IIb-IIIa complex.

1985 • 158 citations

Arg-Gly-Asp recognition by a cell adhesion receptor requires its 130-kDa alpha subunit.

1987 • 137 citations

Structure of platelet glycoprotein IIIa. A common subunit for two different membrane receptors.

1988 • 122 citations

Deleted Work

1955 • 0 citations

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A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive… (1989) – Cell | Metascience Observatory Explorer