Expression of the Mouse Dihydrofolate Reductase Complementary Deoxyribonucleic Acid in Simian Virus 40 Vectors

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Rapid Isolation of Antigens from Cells with A Staphylococcal Protein A-Antibody Adsorbent: Parameters of the Interaction of Antibody-Antigen Complexes with Protein A

1975 • 3,054 citations

Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes.

1977 • 2,233 citations

Preparative and analytical purification of DNA from agarose.

1979 • 1,585 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

The Genome of Simian Virus 40

1978 • 948 citations

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

1980 • 903 citations

How do eucaryotic ribosomes select initiation regions in messenger RNA?

1978 • 830 citations

Spliced early mRNAs of simian virus 40

1978 • 817 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

Transfer of proteins from gels to diazobenzyloxymethyl-paper and detection with antisera: a method for studying antibody specificity and antigen structure.

1979 • 722 citations

Regulation of Simian Virus 40 Transcription: Sensitive Analysis of the RNA Species Present Early in Infections by Virus or Viral DNA

1979 • 623 citations

Crystalline Dihydropteroylglutamic Acid

1960 • 461 citations

Regulation of tumor antigen synthesis by simain virus 40 gene A

1975 • 435 citations

Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase

1978 • 426 citations

Heterogeneity and 5′-terminal structures of the late RNAs of simian virus 40

1978 • 372 citations

Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome

1979 • 355 citations

Splicing and the formation of stable RNA

1979 • 274 citations

Evaluation of the “scanning model” for initiation of protein synthesis in eucaryotes

1980 • 223 citations

Structure and genomic organization of the mouse dihydrofolate reductase gene

1980 • 218 citations

Defective simian virus 40 genomes: Isolation and growth of individual clones

1974 • 201 citations

Synthetic lacoperator DNA is functional in vivo

1976 • 196 citations

Mapping the spliced and unspliced late lytic SV40 RNAs

1978 • 193 citations

Construction of hybrid viruses containing SV40 and $lambda; phage DNA segments and their propagation in cultured monkey cells

1976 • 150 citations

SV40 recombinants carrying rabbit β-globin gene coding sequences

1979 • 139 citations

Factors governing the expression of a bacterial gene in mammalian cells.

1981 • 126 citations

SV40 recombinants carrying a functional RNA splice junction and polyadenylation site from the chromosomal mouse βmaj globin gene

1979 • 91 citations

A rapid radioassay for folic acid reductase and amethopterin

1966 • 76 citations

Purification, Properties, and Synthesis of Dihydrofolate Reductase from Wild Type and Methotrexate-resistant Hamster Cells

1972 • 72 citations

Construction, propagation and expression of simian virus 40 recombinant genomes containing the Escherichia coli gene for thymidine kinase and a Saccharomyces cerevisae gene for tyrosine transfer RNA

1979 • 34 citations

Multiple Free Viral DNA Copies in Polyoma Virus-Transformed Mouse Cells Surviving Productive Infection

1977 • 22 citations