A 13-Amino Acid Amphipathic α-Helix Is Required for the Functional Interaction between the Transcriptional Repressor Mad1 and mSin3A

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1998 • 3,363 citations

Histone acetylation in chromatin structure and transcription

1997 • 2,834 citations

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1998 • 2,686 citations

Histone acetylation and transcriptional regulatory mechanisms

1998 • 1,793 citations

Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase

1997 • 1,251 citations

Retinoblastoma protein recruits histone deacetylase to repress transcription

1998 • 1,231 citations

A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

1997 • 1,218 citations

Rb Interacts with Histone Deacetylase to Repress Transcription

1998 • 965 citations

Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

1997 • 945 citations

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1998 • 919 citations

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

1997 • 856 citations

The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities

1998 • 791 citations

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

1993 • 786 citations

Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A

1997 • 739 citations

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

1997 • 714 citations

Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity

1993 • 711 citations

Identification of a New Family of Tissue-Specific Basic Helix-Loop-Helix Proteins with a Two-Hybrid System

1995 • 655 citations

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein.

1994 • 644 citations

HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

1996 • 623 citations

Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

1995 • 587 citations

Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptide

1992 • 582 citations

Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex

1997 • 565 citations

Eukaryotic Transcription: An Interlaced Network of Transcription Factors and Chromatin-Modifying Machines

1998 • 561 citations

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

1994 • 560 citations

Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters

1997 • 546 citations

An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3

1995 • 372 citations

Targeting Chromatin Disruption: Transcription Regulators that Acetylate Histones

1996 • 369 citations

Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs

1997 • 363 citations

Quantitative Determination of Helical Propensities from Trifluoroethanol Titration Curves

1994 • 323 citations

Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.

1994 • 294 citations

Induced α Helix in the VP16 Activation Domain upon Binding to a Human TAF

1997 • 286 citations

Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites.

1997 • 248 citations

Ordered conformation of polypeptides and proteins in acidic dodecyl sulfate solution

1981 • 226 citations

Chromatin Remodeling and the Control of Gene Expression

1997 • 224 citations

SAP30, a Component of the mSin3 Corepressor Complex Involved in N-CoR-Mediated Repression by Specific Transcription Factors

1998 • 212 citations

Covalent modifications of histones: expression from chromatin templates

1998 • 198 citations

Chromatin remodeling machines: similar motors, ulterior motives

1998 • 175 citations

The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes

1998 • 171 citations

Mad Proteins Contain a Dominant Transcription Repression Domain

1996 • 163 citations

Trifluoroethanol Promotes Helix Formation by Destabilizing Backbone Exposure: Desolvation Rather than Native Hydrogen Bonding Defines the Kinetic Pathway of Dimeric Coiled Coil Folding

1998 • 163 citations

The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs.

1990 • 156 citations

Analysis of an Activator:Coactivator Complex Reveals an Essential Role for Secondary Structure in Transcriptional Activation

1998 • 155 citations

Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1.

1994 • 125 citations

Inhibition of Cell Proliferation by the Mad1 Transcriptional Repressor

1996 • 119 citations

Expression of the mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro.

1995 • 98 citations

Structure-function analysis of the TBP-binding protein Dr1 reveals a mechanism for repression of class II gene transcription.

1994 • 93 citations

The Transcriptional Repressor Even-skipped Interacts Directly with TATA-Binding Protein

1995 • 93 citations

Transcriptional Activator−Coactivator Recognition: Nascent Folding of a Kinase-Inducible Transactivation Domain Predicts Its Structure on Coactivator Binding

1998 • 87 citations

Repression of Myc-Ras cotransformation by Mad is mediated by multiple protein-protein interactions.

1995 • 61 citations

SIN3-Dependent Transcriptional Repression by Interaction with the Mad1 DNA-Binding Protein

1996 • 60 citations