Inhibition of Cell Proliferation by the Mad1 Transcriptional Repressor

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

Production of high-titer helper-free retroviruses by transient transfection.

1993 • 2,280 citations

p53 function and dysfunction

1992 • 1,918 citations

Cyclin D1 is a nuclear protein required for cell cycle progression in G1.

1993 • 1,605 citations

Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD

1995 • 1,154 citations

p53-Independent Expression of p21 ^Cip1 in Muscle and Other Terminally Differentiating Cells

1995 • 1,058 citations

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts.

1993 • 1,057 citations

Acceleration of the G₁/S Phase Transition by Expression of Cyclins Dl and E with an Inducible System

1994 • 986 citations

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

1993 • 786 citations

Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity

1993 • 711 citations

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1987 • 696 citations

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system.

1994 • 659 citations

Novel INK4 Proteins, p19 and p18, Are Specific Inhibitors of the Cyclin D-Dependent Kinases CDK4 and CDK6

1995 • 657 citations

The MYC protein activates transcription of the alpha-prothymosin gene.

1991 • 589 citations

Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

1995 • 587 citations

Levels of c-myc oncogene mRNA are invariant throughout the cell cycle

1985 • 426 citations

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.

1991 • 392 citations

An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3

1995 • 372 citations

c-myc oncogene protein synthesis is independent of the cell cycle in human and avian cells

1985 • 371 citations

Myc—Max—Mad: a transcription factor network controlling cell cycle progression, differentiation and death

1994 • 365 citations

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor)

1987 • 357 citations

A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation.

1993 • 294 citations

Enforced expression of the c-myc oncogene inhibits cell differentiation by precluding entry into a distinct predifferentiation state in G0/G1.

1988 • 273 citations

IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: Demonstration of a novel role for c-myc

1992 • 242 citations

Mutation of the MXI1 gene in prostate cancer

1995 • 207 citations

Cloning and characterization of murine p16INK4a and p15INK4b genes.

1995 • 197 citations

Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling

1991 • 175 citations

Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc.

1994 • 159 citations

Regulation of Myc and Mad during epidermal differentiation and HPV-associated tumorigenesis.

1995 • 146 citations

Myc and Max function as a nucleoprotein complex

1992 • 143 citations

Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1.

1994 • 125 citations

Rescue of defective mitogenic signaling by D-type cyclins.

1995 • 111 citations

Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells

1995 • 106 citations

The functions of Myc proteins

1992 • 103 citations

Expression of the mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro.

1995 • 98 citations

Mitosis-specific phosphorylation of the nuclear oncoproteins Myc and Myb.

1992 • 93 citations

Cell cycle regulation of the c-Myc transcriptional activation domain.

1993 • 71 citations

Differential regulation of Max and role of c-Myc during erythroid and myelomonocytic differentiation of K562 cells.

1995 • 64 citations

Repression of Myc-Ras cotransformation by Mad is mediated by multiple protein-protein interactions.

1995 • 61 citations

Differential effects by Mad and Max on transformation by cellular and viral oncoproteins.

1995 • 57 citations

Quantitative variation of the common acute lymphoblastic leukemia antigen (gp100) on leukemic marrow blasts.

1984 • 33 citations

Cloning and characterization of murine p16(INK4a) and p15(INK4b) genes

1995 • 31 citations