Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Isolation and characterization of autophagy‐defective mutants of Saccharomyces cerevisiae

1993 • 1,649 citations

Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction.

1992 • 1,187 citations

The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

1987 • 850 citations

The fungal vacuole: composition, function, and biogenesis

1990 • 758 citations

Autophagy and related mechanisms of lysosome-mediated protein degradation

1994 • 506 citations

Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae.

1987 • 504 citations

Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization

1994 • 480 citations

Lysosomes : their role in protein breakdown

1987 • 435 citations

Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers

1990 • 376 citations

Novel System for Monitoring Autophagy in the Yeast Saccharomyces cerevisiae

1995 • 344 citations

IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein.

1990 • 305 citations

Genes necessary for directed axonal elongation or fasciculation in C. elegans

1992 • 245 citations

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

1994 • 157 citations

Dual regulation of the expression of the polyubiquitin gene by cyclic AMP and heat shock in yeast.

1988 • 128 citations

Ubiquitin-dependent protein degradation: a cellular perspective

1992 • 96 citations

Chapter 1 A Hitchhiker's Guide to Analysis of the Secretory Pathway in Yeast

1989 • 88 citations

Control of Saccharomyces cerevisiae Catalase T Gene (CTT1) Expression by Nutrient Supply via the RAS-Cyclic AMP Pathway

1989 • 87 citations

IRA2, a Second Gene of Saccharomyces cerevisiae That Encodes a Protein with a Domain Homologous to Mammalian ras GTPase-Activating Protein

1990 • 83 citations

Control of Saccharomyces cerevisiae catalase T gene (CTT1) expression by nutrient supply via the RAS-cyclic AMP pathway.

1989 • 58 citations

Inhibition of Autophagy and Multiple Steps in Asialoglycoprotein Endocytosis by Inhibitors of Tyrosine Protein Kinases (Tyrphostins)

1995 • 48 citations