Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells.

1988 • 1,737 citations

The fungal vacuole: composition, function, and biogenesis

1990 • 758 citations

A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

1989 • 570 citations

Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack

1988 • 389 citations

Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information.

1988 • 287 citations

Endocytosis in yeast: Several of the yeast secretory mutants are defective in endocytosis

1985 • 280 citations

EXTRALYSOSOMAL PROTEIN DEGRADATION

1986 • 279 citations

Active transport of basic amino acids driven by a proton motive force in vacuolar membrane vesicles of Saccharomyces cerevisiae.

1981 • 250 citations

Natural substrates of the Ubiquitin proteolytic pathway

1991 • 238 citations

Glucagon-induced autophagy and proteolysis in rat liver: mediation by selective deprivation of intracellular amino acids.

1979 • 231 citations

Lysosomal (Vacuolar) Proteinases of Yeast Are Essential Catalysts for Protein Degradation, Differentiation, and Cell Survival

1989 • 230 citations

Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes.

1990 • 218 citations

Vacuoles: The sole compartments of digestive enzymes in yeast (Saccharomyces cerevisiae)?

1979 • 202 citations

THE SYNTHESIS AND FUNCTION OF PROTEASES IN SACCHAROMYCES: GENETIC APPROACHES

1984 • 179 citations

Regulated import and degradation of a cytosolic protein in the yeast vacuole

1991 • 174 citations

Macromolecule Synthesis and Breakdown in Relation to Sporulation and Meiosis in Yeast

1974 • 154 citations

Proteinases, proteolysis and biological control in the yeast Saccharomyces cerevisiae

1985 • 135 citations

Acetate Utilization and Macromolecular Synthesis During Sporulation of Yeast

1969 • 131 citations

Proteolytic activities in yeast

1975 • 124 citations

Intracellular Sorting and Processing of a Yeast Vacuolar Hydrolase: Proteinase A Propeptide Contains Vacuolar Targeting Information

1988 • 121 citations

PROTEIN DEGRADATION, MEIOSIS AND SPORULATION IN PROTEINASE-DEFICIENT MUTANTS OF SACCHAROMYCES CEREVISIAE

1981 • 115 citations

Transmission and scanning electron microscopic examination of intracellular organelles in freeze‐substituted Kloeckera and Saccharomyces cerevisiae Yeast Cells

1987 • 95 citations

Subcellular localization and levels of aminopeptidases and dipeptidase in Saccharomyces cerevisiae

1978 • 90 citations

Protein Degradation and Proteinases during Yeast Sporulation

1976 • 89 citations

Isolation and characterization of aminopeptidase mutants of Saccharomyces cerevisiae

1983 • 83 citations

Effects of glucose and nitrogen source on the levels of proteinases, peptidases, and proteinase inhibitors in yeast

1977 • 76 citations

Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins.

1989 • 72 citations

Studies on a Proteinase B Mutant of Yeast

1979 • 68 citations

Analysis of Proteinase A Function in Yeast

1981 • 58 citations

Proteinase activities of Saccharomyces cerevisiae during sporulation

1975 • 58 citations

Proteolytic activity of intact yeast cells during sporulation

1968 • 30 citations

Synthesis and maturation of the yeast vacuolar enzymes carboxypeptidase Y and aminopeptidase I

1983 • 28 citations