The Long Terminal Repeats of Human Immunodeficiency Virus Type-1 and Human T-cell Leukemia Virus Type-I Are Activated by 12-O-Tetradecanoylphorbol- 13-acetate through Different Pathways

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Protein kinase C and lipid signaling for sustained cellular responses

1995 • 2,527 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

Chelerythrine is a potent and specific inhibitor of protein kinase C

1990 • 1,208 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1991 • 1,071 citations

Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

1991 • 626 citations

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

1989 • 549 citations

Human Immunodeficiency Viruses

1986 • 476 citations

Activation of the HIV-1 LTR by T Cell Mitogens and the Trans-Activator Protein of HTLV-I

1987 • 460 citations

Molecular aspects of cellular regulation

1980 • 394 citations

Ras-Mediated Phosphorylation of a Conserved Threonine Residue Enhances the Transactivation Activities of c-Ets1 and c-Ets2

1996 • 325 citations

Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro.

1988 • 309 citations

Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction.

1989 • 289 citations

Activation of human immunodeficiency virus type 1 by DNA damage in human cells

1988 • 256 citations

Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60.

1986 • 255 citations

Regulation of Phospholipase D in HL-60 Granulocytes

1989 • 250 citations

The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1.

1990 • 189 citations

Phorbol myristate acetate: a mitogen selective for a T-lymphocyte subpopulation.

1977 • 188 citations

Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1.

1993 • 180 citations

Signaling through T lymphocyte surface proteins, TCR/CD3 and CD28, activates the HIV-1 long terminal repeat.

1989 • 171 citations

Molecular Aspects of Cellular Regulation

1986 • 168 citations

Phorbol ester enhances human immunodeficiency virus-promoted gene expression and acts on a repeated 10-base-pair functional enhancer element.

1987 • 164 citations

Direct Stimulation of Vav Guanine Nucleotide Exchange Activity for Ras by Phorbol Esters and Diglycerides

1994 • 132 citations

UV-induced transcription from the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and UV-induced secretion of an extracellular factor that induces HIV-1 transcription in nonirradiated cells

1989 • 119 citations

Human T lymphocyte activation by tumor promoters: role of protein kinase C.

1987 • 106 citations

In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter.

1987 • 100 citations

Regulation of protein kinase C isoform proteins in phorbol ester-stimulated Jurkat T lymphoma cells.

1993 • 97 citations

Human T-cell leukemia virus type-1 (HTLV-1) Tax is expressed at the same level in infected cells of HTLV-1-associated myelopathy or tropical spastic paraparesis patients as in asymptomatic carriers but at a lower level in adult T-cell leukemia cells

1995 • 93 citations

Selective post-transcriptional down-regulation of protein kinase C isoenzymes in leukemic T cells chronically treated with phorbol ester.

1990 • 89 citations

The AP-1 complex and its role in transcriptional control by protein kinase C

1991 • 87 citations

A 36-kilodalton cellular transcription factor mediates an indirect interaction of human T-cell leukemia/lymphoma virus type I TAX1 with a responsive element in the viral long terminal repeat.

1990 • 81 citations

Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I

1991 • 75 citations

Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides.

1994 • 75 citations

Protein kinase C and tumor promoters

1990 • 69 citations

The human foamy virus internal promoter is required for efficientgene expression and infectivity

1995 • 46 citations

Myb protein binds to multiple sites in the human T cell lymphotropic virus type 1 long terminal repeat and transactivates LTR-mediated expression

1992 • 45 citations

Awakenings ... UV Light and HIV Gene Activation

1992 • 34 citations

Sequence-Specific Binding of the Transcription Factor c-Ets1 to the Human Immunodeficiency Virus Type I Long Terminal Repeat

1993 • 27 citations

Inhibitors of 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA)‐induced multinucleated cell formation and HTLV‐I p19 antigen expression in HTLV‐I‐infected T‐cell line KH‐2Lo

1986 • 19 citations

Plant‐derived diterpene esters enhance HTLV‐I‐induced colony formation of lymphocytes in co‐culture

1986 • 13 citations

Human Retroviruses and Demyelinating Diseases

1995 • 13 citations

Effect of tumor promoters on human T cell leukemia/lymphoma virus (HTLV)-structural protein induction in adult T-cell leukemia cells

1984 • 12 citations

Evidence for protein kinase C — independent pathways mediating phorbol ester induced plasmacytoid differentiation of B chronic lymphocytic leukemia cells

1991 • 11 citations

Stimulation of virus production and induction of self-syncytium formation in human T-cell leukemia virus type I- and type II-infected T cells by 12-O-tetradecanoylphorbol-13-acetate

1994 • 8 citations

Tax-independent stimulation of human T-cell leukemia virus type-I expression and differential effects on its infectivity by subtoxic and toxic doses of 3-methylcholanthrene.

1995 • 6 citations