Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1.

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

1992 • 688 citations

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

1990 • 677 citations

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

1989 • 539 citations

Developmental Expression of Sp1 in the Mouse

1991 • 533 citations

The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation

1990 • 507 citations

Convergence of Ets- and Notch-Related Structural Motifs in a Heteromeric DNA Binding Complex

1991 • 464 citations

The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene

1989 • 460 citations

Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF

1991 • 447 citations

Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism.

1991 • 437 citations

The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins

1990 • 417 citations

Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

1991 • 404 citations

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

1991 • 381 citations

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.

1992 • 362 citations

Identification of Ets- and Notch-Related Subunits in GA Binding Protein

1991 • 358 citations

Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells.

1992 • 338 citations

Muscle-specific expression of the cardiac alpha-actin gene requires MyoD1, CArG-box binding factor, and Sp1.

1990 • 334 citations

Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription

1991 • 311 citations

elk , Tissue-Specific ets -Related Genes on Chromosomes X and 14 Near Translocation Breakpoints

1989 • 261 citations

Spatial and temporal patterns of E74 transcription during Drosophila development

1990 • 254 citations

Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat

1987 • 251 citations

Mammalian ets-1 and ets-2 genes encode highly conserved proteins.

1988 • 248 citations

Distinct Protein Targets for Signals Acting at the c- fos Serum Response Element

1991 • 244 citations

cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.

1992 • 242 citations

Cooperativity and hierarchical levels of functional organization in the SV40 enhancer

1988 • 238 citations

Sequence-Specific Binding of Human Ets-1 to the T Cell Receptor α Gene Enhancer

1990 • 229 citations

Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain.

1990 • 210 citations

PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes.

1989 • 197 citations

Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein

1990 • 195 citations

Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus.

1990 • 192 citations

Temporal and tissue-specific expression of mouse ets genes.

1987 • 191 citations

The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1.

1990 • 189 citations

erg , a Human ets -Related Gene on Chromosome 21: Alternative Splicing, Polyadenylation, and Translation

1987 • 178 citations

Evolutionarily conserved Ets family members display distinct DNA binding specificities.

1992 • 175 citations

The erg gene: a human gene related to the ets oncogene.

1987 • 164 citations

Complementary patterns of expression of c-ets 1, c-myb and c-myc in the blood-forming system of the chick embryo

1989 • 147 citations

Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1.

1990 • 146 citations

DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism.

1992 • 137 citations

Expression of ets genes in mouse thymocyte subsets and T cells.

1989 • 128 citations

Identification of nucleotide preferences in DNA sequences recognised specifically by c-Ets-1 protein

1992 • 124 citations

Identification in chickens of an evolutionarily conserved cellular ets-2 gene (c-ets-2) encoding nuclear proteins related to the products of the c-ets proto-oncogene.

1988 • 122 citations

Zeste encodes a sequence-specific transcription factor that activates the Ultrabithorax promoter in vitro

1988 • 121 citations

Mitogenic stimulation of thymocytes results in the calcium-dependent phosphorylation of c-ets-1 proteins.

1988 • 118 citations

Synergistic activation of a human promoter in vivo by transcription factor Sp1.

1991 • 115 citations

Human P450scc Gene Transcription Is Induced by Cyclic AMP and Repressed by 12-O-Tetradecanoylphorbol-13-Acetate and A23187 through Independent cis Elements

1990 • 109 citations

PU.1 Recruits a Second Nuclear Factor to a Site Important for Immunoglobulin κ 3' Enhancer Activity

1992 • 107 citations

A phorbol ester response element within the human T-cell receptor beta-chain enhancer.

1992 • 103 citations

Definition of an Ets1 Protein Domain Required for Nuclear Localization in Cells and DNA-Binding Activity In Vitro

1989 • 98 citations

A 36-kilodalton cellular transcription factor mediates an indirect interaction of human T-cell leukemia/lymphoma virus type I TAX1 with a responsive element in the viral long terminal repeat.

1990 • 81 citations

High-affinity DNA-protein interactions of the cellular ETS1 protein: the determination of the ETS binding motif.

1991 • 78 citations

Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I

1991 • 75 citations

The c-ets-1 protein is chromatin associated and binds to DNA in vitro.

1989 • 70 citations

A Short-Lived Nuclear Phosphoprotein Encoded by the Human ets-2 Proto-Oncogene Is Stabilized by Activation of Protein Kinase C

1988 • 66 citations

cis-Acting Sequences Required for Inducible Interleukin-2 Enhancer Function Bind a Novel Ets-Related Protein, Elf-1

1992 • 66 citations

Molecular cloning of the mammalian fatty acid synthase gene and identification of the promoter region

1990 • 62 citations

A divergent ets-related protein, elk-1, recognizes similar c-ets-1 proto-oncogene target sequences and acts as a transcriptional activator.

1992 • 62 citations

Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells.

1989 • 61 citations

erg, an ets-related gene, codes for sequence-specific transcriptional activators.

1991 • 59 citations

Two independent activation domains in c-Ets-1 and c-Ets-2 located in non-conserved sequences of the ets gene family.

1992 • 54 citations

Rapid and transient expression of Ets2 in mature macrophages following stimulation with cMGF, LPS, and PKC activators.

1990 • 53 citations

Interaction of host cell proteins with the human T-cell leukemia virus type I transcriptional control region. II. A comprehensive map of protein-binding sites facilitates construction of a simple chimeric promoter responsive to the viral tax2 gene product.

1990 • 49 citations

Several different upstream promoter elements can potentiate transactivation by the BPV-1 E2 protein.

1991 • 49 citations

Myb protein binds to multiple sites in the human T cell lymphotropic virus type 1 long terminal repeat and transactivates LTR-mediated expression

1992 • 45 citations

Analysis of the promoter region and the N-propeptide domain of the human proα2(I) collagen gene

1985 • 42 citations

Two overlapping sequence motifs within the polyomavirus enhancer are independently the targets of stimulation by both the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the Ha-ras oncogene

1989 • 41 citations

Phosphorylation of the ETS-2 protein: regulation by the T-cell antigen receptor-CD3 complex.

1990 • 38 citations

Synergistic Activation of a Human Promoter In Vivo by Transcription Factor Sp1

1991 • 38 citations

Tissue-specific expression and methylation of a thyroglobulin-chloramphenicol acetyltransferase fusion gene in transgenic mice.

1990 • 37 citations

Structure of the human gene encoding the invariant γ-chain of class II histocompatibility antigens

1985 • 34 citations

Identification of a Ets1 variant protein unaffected in its chromatin and in vitro DNA binding capacities by T cell antigen receptor triggering and intracellular calcium rises.

1990 • 31 citations

Analysis of the DNA binding and transcriptional activation properties of the Ets1 oncoprotein.

1992 • 30 citations

Synergism between two distinct elements of the HTLV-I enhancer during activation by the trans-activator of HTLV-I.

1991 • 24 citations

Structure of the Two Promoters of the Human lck Gene: Differential Accumulation of Two Classes of lck Transcripts in T Cells

1989 • 12 citations