Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease.

1982 • 2,170 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

Trans -Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

1984 • 781 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

Viral myb oncogene encodes a sequence-specific DNA-binding activity

1988 • 608 citations

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

1989 • 549 citations

The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation

1990 • 507 citations

A putative second cell-derived oncogene of the avian leukaemia retrovirus E26

1983 • 462 citations

Electrophoretic transfer of proteins and nucleic acids from slab gels to diazobenzylozymethyl cellulose or nitrocellulose sheets

1980 • 442 citations

Tripartite structure of the avian erythroblastosis virus E26 transforming gene

1983 • 430 citations

Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation

1979 • 424 citations

The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins

1990 • 417 citations

Bidirectional SV40 Transcription Mediated by Tandem Sp1 Binding Interactions

1985 • 413 citations

Natural Antibodies to Human Retrovirus HTLV in a Cluster of Japanese Patients with Adult T Cell Leukemia

1982 • 369 citations

Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes.

1986 • 335 citations

Detection of Human T-Cell Lymphoma/Leukemia Virus Type I DNA and Antigen in Spinal Fluid and Blood of Patients with Chronic Progressive Myelopathy

1988 • 279 citations

elk , Tissue-Specific ets -Related Genes on Chromosomes X and 14 Near Translocation Breakpoints

1989 • 261 citations

Isolation of an HTLV-1-like retrovirus from patients with tropical spastic paraparesis

1988 • 257 citations

Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat

1987 • 251 citations

Mammalian ets-1 and ets-2 genes encode highly conserved proteins.

1988 • 248 citations

Transformation of both erythroid and myeloid cells by E26, an avian leukemia virus that contains the myb gene

1982 • 242 citations

A beta-galactosidase hybrid protein targeted to nuclei as a marker for developmental studies.

1987 • 232 citations

Several distinct "CCAAT" box binding proteins coexist in eukaryotic cells.

1988 • 230 citations

Sequence-Specific Binding of Human Ets-1 to the T Cell Receptor α Gene Enhancer

1990 • 229 citations

Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence

1988 • 218 citations

Requirement of multiple copies of a 21-nucleotide sequence in the U3 regions of human T-cell leukemia virus type I and type II long terminal repeats for trans-acting activation of transcription.

1986 • 212 citations

Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain.

1990 • 210 citations

Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein

1990 • 195 citations

Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus.

1990 • 192 citations

Temporal and tissue-specific expression of mouse ets genes.

1987 • 191 citations

The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1.

1990 • 189 citations

erg , a Human ets -Related Gene on Chromosome 21: Alternative Splicing, Polyadenylation, and Translation

1987 • 178 citations

The ets sequence from the transforming gene of avian erythroblastosis virus, E26, has unique domains on human chromosomes 11 and 21: both loci are transcriptionally active.

1985 • 177 citations

Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer.

1986 • 175 citations

The erg gene: a human gene related to the ets oncogene.

1987 • 164 citations

Two cis-acting elements responsible for posttranscriptional trans-regulation of gene expression of human T-cell leukemia virus type I.

1988 • 150 citations

Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1.

1990 • 146 citations

Role of tryptophan repeats and flanking amino acids in Myb-DNA interactions.

1990 • 146 citations

Expression of ets genes in mouse thymocyte subsets and T cells.

1989 • 128 citations

Isolation of cDNAs for DNA-binding proteins which specifically bind to a tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I

1991 • 123 citations

Identification in chickens of an evolutionarily conserved cellular ets-2 gene (c-ets-2) encoding nuclear proteins related to the products of the c-ets proto-oncogene.

1988 • 122 citations

The Sfpi-1 proviral integration site of Friend erythroleukemia encodes the ets-related transcription factor Pu.1

1991 • 121 citations

Mitogenic stimulation of thymocytes results in the calcium-dependent phosphorylation of c-ets-1 proteins.

1988 • 118 citations

Identification and preferential expression in thymic and bursal lymphocytes of a c-ets oncogene-encoded Mr 54,000 cytoplasmic protein.

1986 • 114 citations

A purine-rich DNA sequence motif present in SV40 and lymphotropic papovavirus binds a lymphoid-specific factor and contributes to enhancer activity in lymphoid cells.

1987 • 110 citations

Myeloid and erythroid neoplastic responses to avian defective leukemia viruses in chickens and in quail

1981 • 100 citations

The proto-oncogene c-ets is preferentially expressed in lymphoid cells.

1985 • 98 citations

Definition of an Ets1 Protein Domain Required for Nuclear Localization in Cells and DNA-Binding Activity In Vitro

1989 • 98 citations

Indirect binding of human T-cell leukemia virus type I tax1 to a responsive element in the viral long terminal repeat.

1989 • 85 citations

A 36-kilodalton cellular transcription factor mediates an indirect interaction of human T-cell leukemia/lymphoma virus type I TAX1 with a responsive element in the viral long terminal repeat.

1990 • 81 citations

Purification and characterization of multiple nuclear factors that bind to the TAX-inducible enhancer within the human T-cell leukemia virus type 1 long terminal repeat.

1989 • 81 citations

Transforming capacities and defectiveness of avian leukemia viruses OK10 and E26

1979 • 76 citations

Tax1 induction of the HTLV-I 21 bp enhancer requires cooperation between two cellular DNA-binding proteins.

1990 • 74 citations

The c-ets-1 protein is chromatin associated and binds to DNA in vitro.

1989 • 70 citations

Interaction of cellular proteins with the human T-cell leukemia virus type I transcriptional control region. Purification of cellular proteins that bind the 21-base pair repeat elements.

1990 • 67 citations

Enzymatic amplification of exogenous and endogenous retroviral sequences from DNA of patients with tropical spastic paraparesis.

1988 • 65 citations

Long terminal repeat structure of an american isolate of type I human T-cell leukemia virus

1984 • 63 citations

The Drosophila ets-2 gene: Molecular structure, chromosomal localization, and developmental expression

1988 • 61 citations

Alternative splicing within the chicken c-ets-1 locus: implications for transduction within the E26 retrovirus of the c-ets proto-oncogene

1988 • 56 citations

Rapid and transient expression of Ets2 in mature macrophages following stimulation with cMGF, LPS, and PKC activators.

1990 • 53 citations

The PU.1 transcription factor is the product of the putative oncogene Spi-1

1990 • 51 citations

Interaction of host cell proteins with the human T-cell leukemia virus type I transcriptional control region. II. A comprehensive map of protein-binding sites facilitates construction of a simple chimeric promoter responsive to the viral tax2 gene product.

1990 • 49 citations

Purification and Characterization of Multiple Nuclear Factors That Bind to the TAX-Inducible Enhancer within the Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1989 • 38 citations

Phosphorylation of the ETS-2 protein: regulation by the T-cell antigen receptor-CD3 complex.

1990 • 38 citations

High expression of ets-1 gene in human thymocytes and immature T leukemic cells.

1988 • 33 citations

Identification of a Ets1 variant protein unaffected in its chromatin and in vitro DNA binding capacities by T cell antigen receptor triggering and intracellular calcium rises.

1990 • 31 citations

The Proto-Oncogene c-ets Is Preferentially Expressed in Lymphoid Cells

1985 • 27 citations

Multiple Domains for the Chicken Cellular Sequences Homologous to the v-ets Oncogene of the E26 Retrovirus

1987 • 26 citations

Localization and modulation of the DNA-binding activity of the human c-ets-1 protooncogene.

1990 • 11 citations