Evidence for protein kinase C — independent pathways mediating phorbol ester induced plasmacytoid differentiation of B chronic lymphocytic leukemia cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Cloning and expression of multiple protein kinase C cDNAs

1986 • 683 citations

Protein kinase C activation by diacylglycerol second messengers

1986 • 498 citations

Structure of the FBJ murine osteosarcoma virus genome: molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cells.

1983 • 282 citations

Phorbol ester-induced differentiation of chronic lymphocytic leukaemia cells

1980 • 258 citations

Regulation of Phospholipase D in HL-60 Granulocytes

1989 • 250 citations

Induction of proliferation and Ig production in human B leukemic cells by anti-immunoglobulins and T cell factors.

1982 • 201 citations

Possible function of the c-myc product: promotion of cellular DNA replication.

1987 • 156 citations

Complexity of the primary genetic response to mitogenic activation of human T cells.

1989 • 149 citations

Heterogeneity of B-cell leukemias demonstrated by the monoclonal antibody FMC7

1981 • 146 citations

The molecules controlling B lymphocytes

1987 • 104 citations

Interleukin 2-induced proliferation of leukemic human B cells.

1985 • 100 citations

Role of Cyclic Adenosine 3′,5′-Monophosphate in Lymphocyte Mitogenesis

1974 • 96 citations

Lineage relationship of chronic lymphocytic leukemia and hairy cell leukemia: Studies with TPA

1984 • 54 citations

Cell cycle progression of B-chronic lymphocytic leukemia cells induced to differentiate by TPA

1988 • 43 citations

Chronic Lymphocytic Leukaemia Cells Activated in Vitro Reveal Cellular Changes that Characterize B‐Prolymphocytic Leukaemia and Immunocytoma

1983 • 42 citations

Cell-type-specific early response gene expression during plasmacytoid differentiation of human B lymphocytic leukemia cells

1990 • 39 citations

The protein kinase C inhibitor H-7, inhibits antigen and IL-2-induced proliferation of murine T cell lines

1987 • 39 citations

In vitro enhancement of immunoglobulin gene expression in chronic lymphocytic leukemia.

1984 • 38 citations

Inhibition of antibodies to CD3 surface antigen and phytohemagglutinin-mediated T cellular responses by inhibiting Ca2+/phospholipid-dependent protein kinase activity with the aid of 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride.

1987 • 38 citations

Chronic lymphocytic leukaemia and its relationship to normal B lymphopoiesis

1982 • 34 citations

Are cyclic nucleotides involved in the initiation of mitogenic activation of human lymphocytes?

1985 • 34 citations

Rapid down‐regulation of protein kinase C and membrane association in phorbol ester‐treated leukemia cells

1985 • 34 citations

Complement- and IgE-mediated release of histamine from basophils in vitro. V. Differential effects of drugs modulating arachidonic acid metabolism.

1985 • 30 citations

Inhibition of Cytotoxic T Lymphocyte-mediated Lysis and Cellular Proliferation by Isoquinoline Sulfonamide Protein Kinase Inhibitors

1989 • 30 citations

Inhibitors of protein kinase C block activation of B lymphocytes by bacterial lipopolysaccharide

1987 • 27 citations

Effects of recombinant interferon-alpha and -gamma on B-CLL cells in serum-free medium: expression of activation, differentiation, and CALLA antigens.

1987 • 25 citations

Interferon induces proliferation and differentiation in primary chronic lymphocytic leukaemia cells.

1985 • 24 citations

Induction and Regulation of Human Interleukin 2 Gene Expression: Significance of Protein Kinase C Activation1

1986 • 24 citations

Recent advances in haematology

1999 • 13 citations

Patterns of gene expression during plasmacytoid differentiation of chronic lymphocytic leukaemia cells

1987 • 7 citations

Patterns of nuclear proto-oncogene expression during induced differentiation and proliferation of human B chronic lymphocytic leukaemia cells.

1990 • 6 citations

Analysis and isolation of leukaemic and residual normal B lymphocyte populations from patients with chronic lymphocytic leukaemia.

1987 • 3 citations