Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1998 • 1,288 citations

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1998 • 1,210 citations

Nucleation of microtubule assembly by a γ-tubulin-containing ring complex

1995 • 851 citations

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

1995 • 822 citations

Centrosome aberrations: cause or consequence of cancer progression?

2002 • 725 citations

Human TPX2 is required for targeting Aurora-A kinase to the spindle

2002 • 563 citations

Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans

2001 • 417 citations

The pericentriolar material in Chinese hamster ovary cells nucleates microtubule formation

1977 • 416 citations

A Novel Mechanism for Activation of the Protein Kinase Aurora A

2003 • 358 citations

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

2003 • 341 citations

The Sudden Recruitment of γ-Tubulin to the Centrosome at the Onset of Mitosis and Its Dynamic Exchange Throughout the Cell Cycle, Do Not Require Microtubules

1999 • 339 citations

Spindle Assembly in Xenopus Egg Extracts: Respective Roles of Centrosomes and Microtubule Self-Organization

1997 • 335 citations

It takes two to tango

2003 • 335 citations

Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules

2002 • 324 citations

Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells.

1998 • 324 citations

“It Takes Two to Tango”: understanding how centrosome duplication is regulated throughout the cell cycle

2001 • 279 citations

Drosophila Aurora-A Is Required for Centrosome Maturation and Actin-Dependent Asymmetric Protein Localization during Mitosis

2002 • 257 citations

The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly

1998 • 240 citations

The Centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila

1999 • 227 citations

Microtubule-nucleating activity of centrosomes in Chinese hamster ovary cells is independent of the centriole cycle but coupled to the mitotic cycle.

1981 • 191 citations

Distinct roles of PP1 and PP2A-like phosphatases in control of microtubule dynamics during mitosis

1997 • 191 citations

Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells

2002 • 135 citations

The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis

1995 • 134 citations

Mutations in centrosomin reveal requirements for centrosomal function during early Drosophila embryogenesis

1999 • 120 citations

XMAP215 Is Required for the Microtubule-Nucleating Activity of Centrosomes

2002 • 101 citations

Mutation of a Drosophila gamma tubulin ring complex subunit encoded by discs degenerate-4 differentially disrupts centrosomal protein localization

2000 • 63 citations

Distribution of pericentriolar material in multipolar spindles induced by colcemid treatment in chinese hamster ovary cells

1988 • 55 citations

Detection of single fluorescent microtubules and methods for determining their dynamics in living cells

1988 • 51 citations

Interaction of an Overexpressed γ-Tubulin with MicrotubulesIn VivoandIn Vitro

1998 • 3 citations