Drosophila Aurora-A Is Required for Centrosome Maturation and Actin-Dependent Asymmetric Protein Localization during Mitosis

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Mitotic kinases as regulators of cell division and its checkpoints

2001 • 1,503 citations

Active and Inactive Protein Kinases: Structural Basis for Regulation

1996 • 1,361 citations

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1998 • 1,210 citations

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

1995 • 822 citations

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

1994 • 749 citations

Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics

2000 • 632 citations

Drosophila Aurora B Kinase Is Required for Histone H3 Phosphorylation and Condensin Recruitment during Chromosome Condensation and to Organize the Central Spindle during Cytokinesis

2001 • 616 citations

Generation of asymmetry and segregation of germ-line granules in early C. elegans embryos

1983 • 534 citations

Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question

1992 • 527 citations

Asymmetric segregation of Numb and Prospero during cell division

1995 • 489 citations

Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans

2001 • 417 citations

Development of adult sensilla on the wing and notum of Drosophila melanogaster

1989 • 383 citations

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts

1999 • 375 citations

prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila

1991 • 360 citations

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

2000 • 332 citations

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

2000 • 326 citations

Heterotrimeric G Proteins Direct Two Modes of Asymmetric Cell Division in the Drosophila Nervous System

2001 • 314 citations

Asymmetric cell division during animal development

2001 • 306 citations

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

2000 • 281 citations

Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell

1999 • 264 citations

Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division

2000 • 249 citations

The Partner of Inscuteable/Discs-Large Complex Is Required to Establish Planar Polarity during Asymmetric Cell Division in Drosophila

2001 • 230 citations

The Centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila

1999 • 227 citations

Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila

1998 • 223 citations

Zygotic development without functional mitotic centrosomes

2001 • 223 citations

Interacting signalling pathways regulating prestalk cell differentiation and movement during the morphogenesis of Dictyostelium.

1993 • 219 citations

Asymmetric Segregation of PIE-1 in C. elegans Is Mediated by Two Complementary Mechanisms that Act through Separate PIE-1 Protein Domains

2000 • 193 citations

asense is a Drosophila neural precursor gene and is capable of initiating sense organ formation

1993 • 186 citations

A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos

1998 • 184 citations

Development of the eye‐antenna imaginal disc and morphogenesis of the adult head in Drosophila melanogaster

1986 • 174 citations

Asymmetric cell division: fly neuroblast meets worm zygote

2001 • 160 citations

Asymmetric cell division in the Drosophila nrevous system

2001 • 128 citations

The Homeotic Target Gene centrosomin Encodes an Essential Centrosomal Component

1996 • 127 citations

Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage

2000 • 111 citations

cdc2 links the Drosophila cell cycle and asymmetric division machineries

2001 • 100 citations

Modes of Protein Movement that Lead to the Asymmetric Localization of Partner of Numb during Drosophila Neuroblast Division

1999 • 98 citations

The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization

1997 • 94 citations

A glial cell arises from an additional division within the mechanosensory lineage during development of the microchaete on the Drosophila notum

1999 • 80 citations

Lineage diversity in the Drosophila nervous system

2001 • 30 citations