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A Novel Mechanism for Activation of the Protein Kinase Aurora A

Data up to Jan 2025

Published2003
Citations358
References28

Total Citations Per Year

Abstract

References (28)

Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases

2002 • 4,097 citations

Mitotic kinases as regulators of cell division and its checkpoints

2001 • 1,503 citations

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1998 • 1,288 citations

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1998 • 1,210 citations

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

2002 • 651 citations

Phospho-Regulation of Kinetochore-Microtubule Attachments by the Aurora Kinase Ipl1p

2002 • 612 citations

Ran Induces Spindle Assembly by Reversing the Inhibitory Effect of Importin α on TPX2 Activity

2001 • 592 citations

Human TPX2 is required for targeting Aurora-A kinase to the spindle

2002 • 563 citations

Chromosomal passengers and the (aurora) ABCs of mitosis

2001 • 535 citations

The spindle: a dynamic assembly of microtubules and motors

2001 • 511 citations

MAPKK-Independent Activation of p38α Mediated by TAB1-Dependent Autophosphorylation of p38α

2002 • 507 citations

The Mitotic Spindle: A Self-Made Machine

2001 • 447 citations

Tpx2, a Novel Xenopus Map Involved in Spindle Pole Organization

2000 • 363 citations

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

2002 • 319 citations

Aurora B Kinase Exists in a Complex with Survivin and INCENP and Its Kinase Activity Is Stimulated by Survivin Binding and Phosphorylation

2002 • 318 citations

Spindle Assembly in Animal Cells

2000 • 281 citations

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

2000 • 281 citations

Phosphorylation of the Carboxyl Terminus of Inner Centromere Protein (INCENP) by the Aurora B Kinase Stimulates Aurora B Kinase Activity

2002 • 262 citations

The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly

1998 • 240 citations

Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A

2002 • 223 citations

The Xenopus laevis Aurora-related Protein Kinase pEg2 Associates with and Phosphorylates the Kinesin-related Protein XlEg5

1999 • 218 citations

Interaction and Feedback Regulation between STK15/BTAK/Aurora-A Kinase and Protein Phosphatase 1 through Mitotic Cell Division Cycle

2001 • 189 citations

Aurora-B associated protein phosphatases as negative regulators of kinase activation

2002 • 151 citations

The kinase Eg2 is a component of the Xenopus oocyte progesterone-activated signaling pathway

1998 • 147 citations

hTPX2 Is Required for Normal Spindle Morphology and Centrosome Integrity during Vertebrate Cell Division

2002 • 142 citations

Progesterone regulates the accumulation and the activation of Eg2 kinase in Xenopus oocytes

2000 • 76 citations

The Xenopus laevis Aurora/Ip11p-Related Kinase pEg2 Participates in the Stability of the Bipolar Mitotic Spindle

2000 • 67 citations

The non-catalytic domain of the Xenopus laevis auroraA kinase localises the protein to the centrosome

2001 • 51 citations

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A Novel Mechanism for Activation of the Protein Kinase Aurora A (2003) – Current Biology | Metascience Observatory Explorer