Interleukin-4 down-regulates MHC class II antigens on cultured rat astrocytes

Acquisition of Lymphokine-Producing Phenotype by CD4+ T Cells

1994 • 1,573 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Inducible expression of H–2 and Ia antigens on brain cells

1984 • 656 citations

Synthesis of nitric oxide in CNS glial cells

1993 • 627 citations

Nitric oxide and asthmatic inflammation

1995 • 514 citations

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation.

1985 • 440 citations

Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells

1994 • 377 citations

Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes

1994 • 246 citations

Inducible nitric oxide synthase activity of cloned murine microglial cells

1993 • 218 citations

The Costimulatory Molecule B7 is Expressed on Human Microglia in Culture and in Multiple Sclerosis Acute Lesions

1995 • 205 citations

Expression of Ia antigens by cultured astrocytes treated with gamma-interferon

1983 • 182 citations

INTERLEUKIN-1BETAINCREASES PROSTAGLANDIN E₂IN RAT ASTROCYTE CULTURES: MODULATORY EFFECT OF NEUROPEPTIDES

1989 • 173 citations

Antigen presentation in the central nervous system. The inhibitory effect of IL-10 on MHC class II expression and production of cytokines depends on the inducing signals and the type of cell analyzed.

1994 • 168 citations

B7/BB‐1 antigen expression on adult human microglia studied in vitro and in situ

1994 • 167 citations

Increased transforming growth factor‐β, interleukin‐4, and interferon‐γ in multiple sclerosis

1994 • 162 citations

Norepinephrine inhibits gamma-interferon-induced major histocompatibility class II (Ia) antigen expression on cultured astrocytes via beta-2-adrenergic signal transduction mechanisms.

1988 • 142 citations

Cytokines Regulate L‐Arginine‐Dependent Cyclic GMP Production in Rat Glial Cells

1993 • 124 citations

Antigen presentation in brain: MHC induction on brain endothelium and astrocytes compared.

1987 • 115 citations

Kinetics of cytokine mRNA production in the brains of mice with progressive toxoplasmic encephalitis

1992 • 109 citations

Human astrocytes are only partially competent antigen presenting cells

1994 • 106 citations

Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway

1994 • 100 citations

Modulation of interferon-gamma-induced major histocompatibility complex class II and Fc receptor expression on isolated microglia by transforming growth factor-beta 1, interleukin-4, noradrenaline and glucocorticoids.

1993 • 95 citations

Interleukin-4 induces proliferation and activation of microglia but suppresses their induction of class II major histocompatibility complex antigen expression

1994 • 93 citations

Induction and regulation of class II major histocompatibility complex mRNA expression in astrocytes by interferon-γ and tumor necrosis factor-α

1990 • 91 citations

Multiple sclerosis Immunomodulatory effects of human astrocytes on T cells

1994 • 88 citations

Interferon γ- and interleukin-4-secreting cells in multiple sclerosis

1993 • 80 citations

Interleukin‐4 and ‐5 as modulators of nerve growth factor synthesis/secretion in astrocytes

1993 • 77 citations

Interleukin-4 (IL-4) induces protein tyrosine phosphorylation of the IL-4 receptor and association of phosphatidylinositol 3-kinase to the IL-4 receptor in a mouse T cell line, HT2

1993 • 76 citations

Regulation of microglial function by interferons

1992 • 58 citations

Comparison and quantitation of Ia antigen expression on cultured macroglia and ameboid microglia from Lewis rat cerebral cortex: analyses and implications

1989 • 56 citations

Primary rat astroglial cultures can generate leukotriene B4

1988 • 41 citations

The interleukin-4 receptor: structure, function, and signal transduction.

1992 • 39 citations

Upregulation and induction of major histocompatibility complex class I and II antigens on microglial cells in early postnatal rat brain following intraperitoneal injections of recombinant interferon-gamma

1994 • 35 citations

Interleukin-4 down-regulates adult human astrocyte DNA synthesis and proliferation.

1993 • 30 citations

The Interleukin-4 Receptor: Structure, Function, and Signal Transduction

1992 • 29 citations

Nitric oxide modulates y-interferon-induced MHC class II antigen expression on rat astrocytes

1995 • 25 citations

Expression of major histocompatibility complex class II antigen on amoeboid microglial cells in early postnatal rat brain following intraperitoneal injections of lipopolysaccharide

1994 • 15 citations

Tumor-induced modulation of macrophage class II MHC molecule mRNA expression

1993 • 15 citations