Modulation of interferon-gamma-induced major histocompatibility complex class II and Fc receptor expression on isolated microglia by transforming growth factor-beta 1, interleukin-4, noradrenaline and glucocorticoids.

Deactivation of macrophages by transforming growth factor-β

1988 • 876 citations

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions.

1991 • 735 citations

Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production

1991 • 579 citations

Microglia are the major cell type expressing MHC class II in human white matter

1987 • 302 citations

Transforming growth factor-beta 1 modulates the expression of class II histocompatibility antigens on human cells.

1988 • 298 citations

Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-gamma and tumor necrosis factor-alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes.

1990 • 214 citations

IL-4 inhibits superoxide production by human mononuclear phagocytes.

1990 • 211 citations

Antagonistic effect of interferon-beta on the interferon-gamma-induced expression of Ia antigen in murine macrophages.

1985 • 207 citations

Continual Breakdown and Regeneration of Myelin in Progressive Multiple Sclerosis Plaquesa

1984 • 171 citations

T cell receptor V alpha-V beta repertoire and cytokine gene expression in active multiple sclerosis lesions.

1992 • 163 citations

Differential susceptibility of activated macrophage cytotoxic effector reactions to the suppressive effects of transforming growth factor-beta 1.

1991 • 147 citations

Norepinephrine inhibits gamma-interferon-induced major histocompatibility class II (Ia) antigen expression on cultured astrocytes via beta-2-adrenergic signal transduction mechanisms.

1988 • 142 citations

IL-4 decreases Fc gamma R membrane expression and Fc gamma R-mediated cytotoxic activity of human monocytes.

1990 • 134 citations

Natural and induced cytotoxicity of oligodendrocytes by microglia is inhibitable by TGFβ

1991 • 126 citations

Opposing effects of glucocorticoids on interferon-gamma-induced murine macrophage Fc receptor and Ia antigen expression.

1985 • 123 citations

Modulation of interleukin-1 and tumor necrosis factor expression by ?-adrenergic agonists in mouse ameboid microglial cells

1991 • 122 citations

Characterisation of microglia isolated from adult human and rat brain

1988 • 117 citations

IL-4 suppresses cytokine gene expression induced by IFN-gamma and/or IL-2 in murine peritoneal macrophages.

1992 • 110 citations

IL-1 expression in human monocytes is transcriptionally and posttranscriptionally regulated by IL-4.

1991 • 102 citations

Transforming growth factors type β1 and β2 suppress rat astrocyte autoantigen presentation and antagonize hyperinduction of class II major histocompatibility complex antigen expression by interferon-γ and tumor necrosis factor-α

1990 • 99 citations

Regulation of MHC class II antigen expression. Opposing effects of tumor necrosis factor-alpha on IFN-gamma-induced HLA-DR and Ia expression depends on the maturation and differentiation stage of the cell.

1991 • 99 citations

Antagonistic and additive effects of IL-4 and lnterferon-γ on human monocytes and macrophages: Effects on Fc receptors, HLA-D antigens, and superoxide production

1990 • 93 citations

Effects of dexamethasone on microglial activation in vivo: selective downregulation of major histocompatibility complex class II expression in regenerating facial nucleus

1991 • 92 citations

Induction of macrophage Ia antigen expression by rIFN-gamma and down-regulation by IFN-alpha/beta and dexamethasone are mediated by changes in steady-state levels of Ia mRNA.

1987 • 89 citations

Differential regulation of class II MHC determinants on macrophages by IFN-gamma and IL-4.

1989 • 87 citations

Regulation of the steady state level of Fc gamma RI mRNA by IFN-gamma and dexamethasone in human monocytes, neutrophils, and U-937 cells.

1990 • 85 citations

Fc receptor density, MHC antigen expression and superoxide production are increased in interferon-gamma-treated microglia isolated from adult rat brain.

1989 • 69 citations

Regulation of Fc receptor and major histocompatibility complex antigen expression on isolated rat microglia by tumour necrosis factor, interleukin-1 and lipopolysaccharide: effects on interferon-gamma induced activation.

1992 • 66 citations

IFN-gamma mediates increased glucocorticoid receptor expression in murine macrophages.

1992 • 56 citations

Hypothalamic noradrenergic pathways exert an influence on neuroendocrine and clinical status in experimental autoimmune encephalomyelitis

1991 • 47 citations

Cytokine regulation of complement receptor-mediated ingestion by mouse peritoneal macrophages. M-CSF and IL-4 activate phagocytosis by a common mechanism requiring autostimulation by IFN-beta.

1991 • 36 citations

Inhibition of neutrophil Fc receptor function by cotricosteroids.

1978 • 27 citations

Effects of hydrocortisone on binding of IgG or C3b-coated erythrocytes to human monocytes and polymorphonuclear leucocytes

1979 • 18 citations