The Crystal Structure of an Unusual Processivity Factor, Herpes Simplex Virus UL42, Bound to the C Terminus of Its Cognate Polymerase

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods

1997 • 1,905 citations

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1994 • 1,669 citations

Atomic Structures of the Human Immunophilin FKBP-12 Complexes with FK506 and Rapamycin

1993 • 1,202 citations

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution

1998 • 1,164 citations

Methods used in the structure determination of bovine mitochondrial F1 ATPase

1996 • 1,101 citations

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

1994 • 899 citations

Proliferating cell nuclear antigen is required for DNA excision repair

1992 • 809 citations

Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA

1996 • 790 citations

Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: A sliding DNA clamp

1992 • 748 citations

Conserved domains in DNA repair proteins and evolution of repair systems

1999 • 551 citations

Analysis of the Complete Nucleotide Sequence of African Swine Fever Virus

1995 • 436 citations

Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme

1991 • 420 citations

Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7.

1987 • 399 citations

Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins

1991 • 380 citations

Building a Replisome from Interacting Pieces

1999 • 368 citations

Identification of genes involved in DNA replication of the Autographa californica baculovirus.

1994 • 302 citations

Protein fold recognition using sequence‐derived predictions

1996 • 299 citations

Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair.

1994 • 268 citations

Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta.

1991 • 254 citations

Sliding Clamps of DNA Polymerases

1993 • 250 citations

The Mitochondrial p55 Accessory Subunit of Human DNA Polymerase γ Enhances DNA Binding, Promotes Processive DNA Synthesis, and Confers N-Ethylmaleimide Resistance

1999 • 223 citations

The Complete DNA Sequence of Lymphocystis Disease Virus

1997 • 222 citations

Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius

1999 • 208 citations

Escherichia coli thioredoxin stabilizes complexes of bacteriophage T7 DNA polymerase and primed templates.

1987 • 207 citations

Substrate requirements of human rhinovirus 3C protease for peptide cleavage in vitro.

1990 • 203 citations

The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity

1990 • 202 citations

Human Homologs of Schizosaccharomyces pombe Rad1, Hus1, and Rad9 Form a DNA Damage-responsive Protein Complex

1999 • 201 citations

A 3D-1D substitution matrix for protein fold recognition that includes predicted secondary structure of the sequence

1997 • 163 citations

Functional interaction between the herpes simplex-1 DNA polymerase and UL42 protein.

1990 • 151 citations

The Human G2 Checkpoint Control Protein hRAD9 Is a Nuclear Phosphoprotein That Forms Complexes with hRAD1 and hHUS1

1999 • 142 citations

Herpes simplex-1 DNA polymerase

1989 • 138 citations

Saccharomyces cerevisiae replication factor C. I. Purification and characterization of its ATPase activity.

1991 • 128 citations

Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage

1998 • 117 citations

The Accessory Subunit of Xenopus laevis Mitochondrial DNA Polymerase γ Increases Processivity of the Catalytic Subunit of Human DNA Polymerase γ and Is Related to Class II Aminoacyl-tRNA Synthetases

1999 • 108 citations

Functional analysis of human cytomegalovirus polymerase accessory protein

1994 • 92 citations

The essential 65-kilodalton DNA-binding protein of herpes simplex virus stimulates the virus-encoded DNA polymerase

1989 • 90 citations

The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: Implications for a dual role as a primer recognition factor and processivity clamp

1999 • 87 citations

Analysis of 74 kb of DNA Located at the Right End of the 330-kb Chlorella Virus PBCV-1 Genome

1997 • 86 citations

The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication

1993 • 82 citations

Identification of the gene encoding the 65-kilodalton DNA-binding protein of herpes simplex virus type 1

1988 • 78 citations

Detecting the ability of viral, bacterial and eukaryotic replication proteins to track along DNA.

1994 • 68 citations

Cloning and Functional Analysis of Kaposi’s Sarcoma-Associated Herpesvirus DNA Polymerase and Its Processivity Factor

1998 • 64 citations

Interaction of herpes simplex virus type 1 DNA polymerase and the UL42 accessory protein with a model primer template

1994 • 61 citations

Functional analysis of the herpes simplex virus UL42 protein

1993 • 58 citations

Specific inhibition of herpes simplex virus DNA polymerase by helical peptides corresponding to the subunit interface.

1995 • 55 citations

Herpes Simplex Virus Processivity Factor UL42 Imparts Increased DNA-Binding Specificity to the Viral DNA Polymerase and Decreased Dissociation from Primer-Template without Reducing the Elongation Rate

2006 • 53 citations

Herpes Simplex Virus Processivity Factor UL42 Imparts Increased DNA-Binding Specificity to the Viral DNA Polymerase and Decreased Dissociation from Primer-Template without Reducing the Elongation Rate

1999 • 50 citations

Cloning, sequencing, and functional characterization of the two subunits of the pseudorabies virus DNA polymerase holoenzyme: evidence for specificity of interaction

1995 • 46 citations

Sequences at the C-terminus of the herpes simplex virus type 1 UL30 protein are dispensable for DNA polymerase activity but not for viral origin-dependent DNA replication

1993 • 45 citations

Interaction between the Herpes Simplex Virus Type 1 Origin-Binding and DNA Polymerase Accessory Proteins

1998 • 45 citations

Intranuclear delivery of an antiviral peptide mediated by the B subunit of Escherichia coli heat-labile enterotoxin

1999 • 42 citations

Role of the Carboxy Terminus of Herpes Simplex Virus Type 1 DNA Polymerase in its Interaction With UL42

1994 • 41 citations

Mutations in the C terminus of herpes simplex virus type 1 DNA polymerase can affect binding and stimulation by its accessory protein UL42 without affecting basal polymerase activity

1993 • 38 citations

Mutations that specifically impair the DNA binding activity of the herpes simplex virus protein UL42

1995 • 38 citations

Bipartite DNA-binding region of the Epstein-Barr virus BMRF1 product essential for DNA polymerase accessory function

1995 • 37 citations

The herpes simplex virus type 1 DNA polymerase accessory protein, UL42, contains a functional protease-resistant domain

1993 • 29 citations

Deletions of the carboxy terminus of herpes simplex virus type 1 UL42 define a conserved amino-terminal functional domain

1993 • 28 citations

The 41-kDa Protein of Human Herpesvirus 6 Specifically Binds to Viral DNA Polymerase and Greatly Increases DNA Synthesis

1998 • 27 citations

Secondary Structure and Structure-Activity Relationships of Peptides Corresponding to the Subunit Interface of Herpes Simplex Virus DNA Polymerase

2000 • 24 citations