Herpes Simplex Virus Processivity Factor UL42 Imparts Increased DNA-Binding Specificity to the Viral DNA Polymerase and Decreased Dissociation from Primer-Template without Reducing the Elongation Rate

Proteins: Structures and Molecular Properties

1986 • 2,694 citations

The Complete DNA Sequence of the Long Unique Region in the Genome of Herpes Simplex Virus Type 1

1988 • 1,618 citations

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

1994 • 899 citations

Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA

1996 • 790 citations

Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: A sliding DNA clamp

1992 • 748 citations

Studies of the binding of Escherichia coli RNA polymerase to DNA

1972 • 459 citations

DNA POLYMERASE III HOLOENZYME: Structure and Function of a Chromosomal Replicating Machine

1995 • 422 citations

Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme

1991 • 420 citations

Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7.

1987 • 399 citations

Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins

1991 • 380 citations

Coupling of a Replicative Polymerase and Helicase: A τ–DnaB Interaction Mediates Rapid Replication Fork Movement

1996 • 358 citations

Smart machines at the DNA replication fork

1994 • 312 citations

Sliding Clamps of DNA Polymerases

1993 • 250 citations

Clamp loading, unloading and intrinsic stability of the PCNA, β and gp45 sliding clamps of human, E. coli and T4 replicases

1996 • 216 citations

Escherichia coli thioredoxin stabilizes complexes of bacteriophage T7 DNA polymerase and primed templates.

1987 • 207 citations

Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1.

1990 • 205 citations

The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity

1990 • 202 citations

Properties of Herpes Simplex Virus DNA Polymerase and Characterization of Its Associated Exonuclease Activity

1979 • 157 citations

Functional interaction between the herpes simplex-1 DNA polymerase and UL42 protein.

1990 • 151 citations

[61] Rapid kinetic analysis of mechanochemical adenosinetriphosphatases

1986 • 151 citations

Herpes simplex-1 DNA polymerase

1989 • 138 citations

A Transcriptional Enhancer Whose Function Imposes a Requirement That Proteins Track Along DNA

1992 • 130 citations

Studies of the binding of Escherichia coli RNA polymerase to DNA

1972 • 124 citations

The 65,000-Mr DNA-binding and virion trans-inducing proteins of herpes simplex virus type 1

1987 • 121 citations

Bacteriophage T7 deoxyribonucleic acid replication invitro. Bacteriophage T7 DNA polymerase: an an emzyme composed of phage- and host-specific subunits.

1975 • 111 citations

The role of palindromic and non-palindromic sequences in arresting DNA synthesis in vitro and in Vivo

1984 • 102 citations

Bacteriophage T7 Deoxyribonucleic Acid Replication in Vitro

1974 • 89 citations

On the Processivity of Polymerases^a

1994 • 84 citations

Preexisting nuclear architecture defines the intranuclear location of herpesvirus DNA replication structures

1994 • 83 citations

The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication

1993 • 82 citations

Formation of herpes simplex virus type 1 replication compartments by transfection: requirements and localization to nuclear domain 10

1997 • 78 citations

DNA-Binding Proteins of Cells Infected by Herpes Simplex Virus Type 1 and Type 2

1976 • 77 citations

Functional interactions between SV40 T antigen and other replication proteins at the replication fork

1993 • 75 citations

Enzymatic activities of overexpressed herpes simplex virus DNA polymerase purified from recombinant baculovirus-infected insect cells

1990 • 69 citations

Assembly of Herpes Simplex Virus Replication Proteins at Two Distinct Intranuclear Sites

1997 • 64 citations

Processive replication of single-stranded DNA templates by the herpes simplex virus-induced DNA polymerase.

1987 • 64 citations

Interaction of herpes simplex virus type 1 DNA polymerase and the UL42 accessory protein with a model primer template

1994 • 61 citations

Replication of Herpesvirus DNA

1981 • 60 citations

Functional analysis of the herpes simplex virus UL42 protein

1993 • 58 citations

Expression of herpes simplex virus type 1 DNA polymerase gene by in vitro translation and effects of gene deletions on activity

1988 • 58 citations

The catalytic subunit of the DNA polymerase of herpes simplex virus type 1 interacts specifically with the C terminus of the UL8 component of the viral helicase-primase complex

1997 • 54 citations

[21] Methods of analyzing processivity

1995 • 52 citations

On the Processivity of DNA Replication

1983 • 49 citations

The T4 DNA polymerase accessory proteins form an ATP-dependent complex on a primer-template junction.

1991 • 48 citations

Structural and functional organization of herpes simplex virus DNA polymerase investigated by limited proteolysis.

1994 • 48 citations

Expression of herpes simplex virus type 1 DNA polymerase in Saccharomyces cerevisiae and detection of virus-specific enzyme activity in cell-free lysates

1988 • 41 citations

Mutations that specifically impair the DNA binding activity of the herpes simplex virus protein UL42

1995 • 38 citations

Protein-Protein and Protein-DNA Interactions at the Bacteriophage T4 DNA Replication Fork

1996 • 37 citations

DNA Polymerase III: Running Rings around the Fork

1996 • 32 citations

Maturation of replicating simian virus 40 DNA molecules in isolated nuclei by continued bidirectional replication to the normal termination region

1979 • 28 citations

On the structure of replication and transcription factories

1995 • 27 citations

Genetic analysis of the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin.

1992 • 25 citations

Replication of herpesvirus DNA. III. Rate of DNA elongation

1977 • 24 citations

The effect of the UL42 protein on the DNA polymerase activity of the catalytic subunit of the DNA polymerase encoded by herpes simplex virus type 1

1992 • 20 citations

Conformational changes induced in herpes simplex virus DNA polymerase upon DNA binding.

1993 • 18 citations

Sequence specificity of pausing by DNA polymerases

1989 • 18 citations

Evidence that the nuclease activities associated with the herpes simplex type 1 DNA polymerase are due to the 3'-5' exonuclease

1996 • 11 citations

Improved band shift assay for the simultaneous analysis of protein—DNA interactions and enzymatic functions of DNA polymerases

1992 • 7 citations