Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius

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1997 • 33,348 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

Complete Genome Sequence of the Methanogenic Archaeon, Methanococcus jannaschii

1996 • 2,043 citations

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

1992 • 1,887 citations

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution

1998 • 1,164 citations

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.

1993 • 1,097 citations

Molecular Biology of Bacteriophage T4

1994 • 881 citations

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

1985 • 855 citations

THE DNA REPLICATION FORK IN EUKARYOTIC CELLS

1998 • 815 citations

Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.

1994 • 694 citations

FUNCTION AND STRUCTURE RELATIONSHIPS IN DNA POLYMERASES

1994 • 611 citations

Compilation, alignment, and phylogenetic relationships of DNA polymerases

1993 • 590 citations

Structures of Ternary Complexes of Rat DNA Polymerase β, a DNA Template-Primer, and ddCTP

1994 • 587 citations

Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro

1994 • 559 citations

Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal

1998 • 520 citations

STRUCTURE AND FUNCTION OF SIMIAN VIRUS 40 LARGE TUMOR ANTIGEN

1992 • 506 citations

EUKARYOTIC DNA POLYMERASES

1991 • 493 citations

Crystal Structure of Rat DNA Polymerase β: Evidence for a Common Polymerase Mechanism

1994 • 464 citations

Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69

1997 • 431 citations

DNA POLYMERASE III HOLOENZYME: Structure and Function of a Chromosomal Replicating Machine

1995 • 422 citations

Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes

1998 • 375 citations

Crystal structure of Thermus aquaticus DNA polymerase

1995 • 355 citations

Polymerases and the Replisome: Machines within Machines

1998 • 350 citations

Cross-validated maximum likelihood enhances crystallographic simulated annealing refinement

1997 • 347 citations

Cocrystal structure of an editing complex of Klenow fragment with DNA.

1988 • 324 citations

High-level Biosynthetic Substitution of Methionine in Proteins by its Analogs 2-Aminohexanoic Acid, Selenomethionine, Telluromethionine and Ethionine in Escherichia coli

1995 • 304 citations

Archaea and the Origin(s) of DNA Replication Proteins

1997 • 267 citations

High-level Biosynthetic Substitution of Methionine in Proteins by its Analogs 2-Aminohexanoic Acid, Selenomethionine, Telluromethionine and Ethionine in Escherichia coli

1995 • 217 citations

DNA replication in eukaryotic cells

1997 • 194 citations

Thermostable DNA Polymerases

1996 • 178 citations

2.3 Å crystal structure of the catalytic domain of DNA polymerase β

1994 • 168 citations

Crystal structure of a thermostable Bacillus DNA polymerase l large fragment at 2.1 Å resolution

1997 • 153 citations

A heterodimeric DNA polymerase: Evidence that members of Euryarchaeota possess a distinct DNA polymerase

1998 • 139 citations

A novel DNA polymerase in the hyperthermophilic archaeon, Pyrococcus furiosus: gene cloning, expression, and characterization

1997 • 127 citations

Crystal Structures of an NH₂-Terminal Fragment of T4 DNA Polymerase and Its Complexes with Single-Stranded DNA and with Divalent Metal Ions

1996 • 102 citations

Coordination of leading and lagging strand DNA synthesis at the replication fork of bacteriophage T7

1994 • 95 citations

Protein‐protein interactions at a DNA replication fork: bacteriophage T4 as a model

1992 • 93 citations

Thermococcus gorgonarius sp. nov. and Thermococcus pacificus sp. nov.: heterotrophic extremely thermophilic archaea from New Zealand submarine hot vents

1998 • 75 citations

Motif A of bacteriophage T4 DNA polymerase: role in primer extension and DNA replication fidelity. Isolation of new antimutator and mutator DNA polymerases.

1994 • 74 citations

Structures of DNA and RNA polymerases and their interactions with nucleic acid substrates

1995 • 70 citations

Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion

1994 • 61 citations

The carboxyl terminus of the bacteriophage T4 DNA polymerase is required for holoenzyme complex formation

1996 • 51 citations

DNA Replication Machinery: Functional Characterization of a Complex Containing DNA Polymerase α, DNA Polymerase δ, and Replication Factor C Suggests an Asymmetric DNA Polymerase Dimer

1996 • 45 citations

Functional Consequences and Exonuclease Kinetic Parameters of Point Mutations in Bacteriophage T₄ DNA Polymerase

1996 • 39 citations

Isolation, characterization, and kinetic properties of truncated forms of T4 DNA polymerase that exhibit 3‘-5‘ exonuclease activity.

1994 • 31 citations