Interaction between the Herpes Simplex Virus Type 1 Origin-Binding and DNA Polymerase Accessory Proteins

Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations.

1992 • 461 citations

HERPES SIMPLEX VIRUS DNA REPLICATION

1997 • 331 citations

Identification of herpes simplex virus type 1 genes required for origin-dependent DNA synthesis

1988 • 328 citations

Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides

1981 • 264 citations

Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein

1988 • 260 citations

Herpes simplex virus 1 helicase-primase: a complex of three herpes-encoded gene products.

1989 • 224 citations

The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity

1990 • 202 citations

Herpes simplex virus DNA replication: the UL9 gene encodes an origin-binding protein.

1988 • 179 citations

Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein

1983 • 179 citations

Functional interaction between the herpes simplex-1 DNA polymerase and UL42 protein.

1990 • 151 citations

Identification of the herpes simplex virus DNA polymerase gene

1977 • 149 citations

A DNA binding protein specific for an origin of replication of herpes simplex virus type 1.

1986 • 136 citations

The herpes simplex virus 1 origin binding protein: a DNA helicase

1991 • 129 citations

Herpesvirus Transcription and Its Regulation

1991 • 118 citations

Physical interaction between the herpes simplex virus 1 origin-binding protein and single-stranded DNA-binding protein ICP8.

1993 • 96 citations

Purification of the herpes simplex virus type 1 65-kilodalton DNA-binding protein: properties of the protein and evidence of its association with the virus-encoded DNA polymerase

1988 • 95 citations

The essential 65-kilodalton DNA-binding protein of herpes simplex virus stimulates the virus-encoded DNA polymerase

1989 • 90 citations

Purification and characterization of UL9, the herpes simplex virus type 1 origin-binding protein

1992 • 89 citations

DNA-binding protein associated with herpes simplex virus DNA polymerase

1985 • 89 citations

Genetics of resistance to phosphonoacetic acid in strain KOS of herpes simplex virus type 1

1977 • 88 citations

The origin binding protein of herpes simplex virus 1 binds cooperatively to the viral origin of replication oris.

1990 • 83 citations

Binding of the herpes simplex virus type 1 UL9 gene product to an origin of viral DNA replication

1989 • 81 citations

The herpes simplex virus type 1 origin-binding protein interacts specifically with the viral UL8 protein

1994 • 81 citations

Identification of the gene encoding the 65-kilodalton DNA-binding protein of herpes simplex virus type 1

1988 • 78 citations

Overexpression and Assembly of the Herpes Simplex Virus Type 1 Helicase-Primase in Insect Cells

1989 • 75 citations

Rolling circle DNA replication in vitro by a complex of herpes simplex virus type 1-encoded enzymes.

1994 • 74 citations

The conserved helicase motifs of the herpes simplex virus type 1 origin-binding protein UL9 are important for function

1992 • 73 citations

Herpes simplex virus type 1 origin-dependent DNA replication in insect cells using recombinant baculoviruses

1992 • 72 citations

Helicase-primase complex of herpes simplex virus type 1: a mutation in the UL52 subunit abolishes primase activity

1994 • 72 citations

Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein

1991 • 70 citations

Inhibition of Herpes Simplex Virus Type 1 DNA Replication by Mutant Forms of the Origin-Binding Protein

1993 • 69 citations

Characterization of nuclear structures in cells infected with herpes simplex virus type 1 in the absence of viral DNA replication

1996 • 66 citations

Assembly of Herpes Simplex Virus Replication Proteins at Two Distinct Intranuclear Sites

1997 • 64 citations

Association of origin binding protein and single strand DNA-binding protein, ICP8, during herpes simplex virus type 1 DNA replication in vivo.

1994 • 63 citations

Interaction of herpes simplex virus type 1 DNA polymerase and the UL42 accessory protein with a model primer template

1994 • 61 citations

Assembly of complete, functionally active herpes simplex virus DNA replication compartments and recruitment of associated viral and cellular proteins in transient cotransfection assays

1997 • 60 citations

Structural elements required for the cooperative binding of the herpes simplex virus origin binding protein to oriS reside in the N-terminal part of the protein.

1992 • 59 citations

Expression of herpes simplex virus type 1 DNA polymerase gene by in vitro translation and effects of gene deletions on activity

1988 • 58 citations

A 269-amino-acid segment with a pseudo-leucine zipper and a helix-turn-helix motif codes for the sequence-specific DNA-binding domain of herpes simplex virus type 1 origin-binding protein

1991 • 55 citations

Genetic analysis of the herpes simplex virus type 1 UL9 gene: Isolation of a lacZ insertion mutant and expression in eukaryotic cells

1992 • 48 citations

Localization of the herpes simplex virus type 1 65-kilodalton DNA-binding protein and DNA polymerase in the presence and absence of viral DNA synthesis

1990 • 45 citations

Cooperative interactions between replication origin-bound molecules of herpes simplex virus origin-binding protein are mediated via the amino terminus of the protein.

1992 • 39 citations

Intracellular Localization of the Herpes Simplex Virus Type-1 Origin Binding Protein, UL9

1996 • 31 citations

The DNA Binding Domain of Herpes Simplex Virus Type 1 Origin Binding Protein Is a Transdominant Inhibitor of Virus Replication

1993 • 30 citations

Two regions of the herpes simplex virus type 1 UL42 protein are required for its functional interaction with the viral DNA polymerase

1993 • 30 citations

Interaction of herpes simplex virus 1 origin-binding protein with DNA polymerase alpha.

1995 • 27 citations

The origin-binding domain of the herpes simplex virus type 1 UL9 protein is not required for DNA helicase activity

1995 • 17 citations

[Herpes simplex virus DNA replication].

1992 • 11 citations