Differential gene expression in CD3e- and RAG1-deficient thymuses: definition of a set of genes potentially involved in thymocyte maturation

Basic local alignment search tool

1990 • 87,358 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

1995 • 9,575 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

[5] Rapid and sensitive sequence comparison with FASTP and FASTA

1990 • 1,983 citations

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

1992 • 1,116 citations

A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression.

1993 • 833 citations

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

1993 • 528 citations

An HMG-box-containing T-cell factor required for thymocyte differentiation

1995 • 518 citations

Cellular Interactions in Thymocyte Development

1996 • 503 citations

Early T Lymphocyte Progenitors

1996 • 473 citations

The thymic microenvironment

1993 • 459 citations

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice.

1994 • 426 citations

Lymphoid Development in Mice Congenitally Lacking T Cell Receptor αβ-Expressing Cells

1992 • 371 citations

BTG1, a member of a new family of antiproliferative genes.

1992 • 298 citations

Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes

1995 • 295 citations

TECK: A Novel CC Chemokine Specifically Expressed by Thymic Dendritic Cells and Potentially Involved in T Cell Development

1997 • 292 citations

The Expression Pattern of the Transcription Factor Phox2 Delineates Synaptic Pathways of the Autonomic Nervous System

1996 • 287 citations

Development in the thymus: it takes two to tango

1993 • 281 citations

Crosstalk in the mouse thymus

1994 • 275 citations

T cell development in mice lacking the CD3-zeta/eta gene.

1993 • 235 citations

Differential Gene Expression in the Murine Thymus Assayed by Quantitative Hybridization of Arrayed cDNA Clones

1995 • 202 citations

Sensitivity Issues in DNA Array-Based Expression Measurements and Performance of Nylon Microarrays for Small Samples

1999 • 194 citations

Characterization and comparison of four serine- and arginine-rich (SR) protein kinases

1997 • 140 citations

Characterization of a Novel Src-like Adapter Protein That Associates with the Eck Receptor Tyrosine Kinase

1995 • 127 citations

Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting.

1991 • 125 citations

Cloning of the mouse BTG3 gene and definition of a new gene family (the BTG family) involved in the negative control of the cell cycle

1997 • 121 citations

Sequencing and cloning of human prolylcarboxypeptidase (angiotensinase C). Similarity to both serine carboxypeptidase and prolylendopeptidase families

1993 • 112 citations

Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions.

1985 • 101 citations

Multiplex messenger assay: simultaneous, quantitative measurement of expression of many genes in the context of T cell activation

1996 • 81 citations

A Thymocyte Factor SATB1 Suppresses Transcription of Stably Integrated Matrix-Attachment Region-Linked Reporter Genes

1997 • 80 citations

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

1998 • 67 citations

Identification of differentialy expressed genes by restirction endonuclease-based gene expression fingerprinting

1995 • 61 citations

Thymocytes and RelB‐dependent medullary epithelial cells provide growth‐promoting and organization signals, respectively, to thymic medullary stromal cells

1997 • 46 citations

From hybridization image to numerical values: a practical, high throughput quantification system for high density filter hybridizations

1996 • 43 citations

CD27 cooperates with the pre-T cell receptor in the regulation of murine T cell development.

1996 • 40 citations

Regulation of mRNA abundance in activated T lymphocytes: identification of mRNA species affected by the inhibition of protein synthesis.

1990 • 32 citations

Establishment and characterization of mouse thymic epithelial cell lines.

1989 • 26 citations

Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2

1987 • 22 citations

Modulation of mRNA levels in the presence of thymocytes and genome mapping for a set of genes expressed in mouse thymic epithelial cells

1997 • 12 citations

Differential mRNA Expression in Untreated and TNF-α Elicited Murine Dendritic Cells Precursors

1997 • 2 citations