Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

The differentiation and function of human T lymphocytes

1980 • 1,548 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.

1975 • 1,105 citations

Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man

1981 • 871 citations

An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences

1982 • 801 citations

Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing

1982 • 744 citations

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

1984 • 652 citations

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

1984 • 528 citations

Neuronal Cell Thy-1 Glycoprotein: Homology with Immunoglobulin

1982 • 524 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

Codon preference and its use in identifying protein coding regions in long DNA sequences

1982 • 476 citations

Somatic recombination in a murine T-cell receptor gene

1984 • 468 citations

Thymus-dependent membrane antigens in man: Inhibition of cell-mediated lympholysis by monoclonal antibodies to T _{H 2} antigen

1981 • 352 citations

The isolation and sequence of the gene encoding T8: A molecule defining functional classes of T lymphocytes

1985 • 325 citations

Lymphocytes as Models for the Study of Mammalian Cellular Differentiation

1977 • 269 citations

The Three-Dimensional Structure of the Fab′ Fragment of a Human Myeloma Immunoglobulin at 2.0-Å Resolution

1974 • 213 citations

Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera

1979 • 208 citations

Selective inhibition of human T cell cytotoxicity at levels of target recognition or initiation of lysis by monoclonal OKT3 and Leu-2a antibodies.

1982 • 185 citations

MRC OX-2 antigen: a lymphoid/neuronal membrane glycoprotein with a structure like a single immunoglobulin light chain.

1985 • 165 citations

Stable transformation of mouse L cells for human membrane T-cell differentiation antigens, HLA and beta 2-microglobulin: selection by fluorescence-activated cell sorting.

1983 • 153 citations

Mouse alloantibodies capable of blocking cytotoxic T-cell function. I. Relationship between the antigen reactive with blocking antibodies and the Lyt-2 locus.

1979 • 146 citations

Lyt-2 and lyt-3 antigens are on two different polypeptide subunits linked by disulfide bonds. Relationship of subunits to T cell cytolytic activity.

1981 • 142 citations

GENETIC CORRELATION OF A MOUSE LIGHT CHAIN VARIABLE REGION MARKER WITH A THYMOCYTE SURFACE ANTIGEN

1974 • 130 citations

Isolation of the gene encoding the human T-lymphocyte differentiation antigen Leu-2 (T8) by gene transfer and cDNA subtraction.

1984 • 108 citations

Immunology: The immunoglobulin superfamily takes shape

1984 • 82 citations

Lyt-2-/Lyt 3- variants of a cloned cytolytic T cell line lack an antigen receptor functional in cytolysis.

1981 • 74 citations

Gene for the human T cell differentiation antigen Leu-2/T8 is closely linked to the kappa light chain locus on chromosome 2.

1985 • 60 citations

Amplification of a gene coding for human T-cell differentiation antigen

1983 • 50 citations

Ly Antigens Associated with T Cell Recognition and Effector Function

1984 • 50 citations

Comparison of Target Antigens of Monoclonal Reagents OKT5, OKT8, and Leu2A, which Inhibit Effector Function of Human Cytotoxic T Lymphocytes

1983 • 26 citations

The mouse antigen complex—II. Structural analysis of the subunits

1984 • 16 citations