Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

The mouse; its reproduction and development

1968 • 1,290 citations

A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression.

1993 • 833 citations

Negative selection of lymphocytes

1994 • 810 citations

Positive selection of lymphocytes

1994 • 563 citations

Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation.

1987 • 505 citations

The thymic microenvironment

1993 • 459 citations

Control points in early T-cell development

1993 • 429 citations

Restoration of T Cell Development in RAG-2-Deficient Mice by Functional TCR Transgenes

1993 • 403 citations

Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation.

1994 • 334 citations

Development in the thymus: it takes two to tango

1993 • 281 citations

Crosstalk in the mouse thymus

1994 • 275 citations

T-Cell Differentiation is Influenced by Thymic Microenvironments

1991 • 239 citations

A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene.

1994 • 233 citations

Monoclonal antibodies to stromal cell types of the mouse thymus

1984 • 228 citations

Towards an integrated view of thymopoiesis

1991 • 205 citations

Disorganization and restoration of thymic medullary epithelial cells in T cell receptor‐negative scid mice: Evidence that receptor‐bearing lymphocytes influence maturation of the thymic microenvironment

1991 • 190 citations

Lymphocyte Development from Stem Cells

1992 • 170 citations

Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor.

1992 • 165 citations

Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation.

1988 • 160 citations

Stromal cell types in the developing thymus of the normal and nude mouse embryo

1985 • 108 citations

Immunohistology of lymphoid and non‐lymphoid cells in the thymus in relation to T lymphocyte differentiation

1984 • 83 citations

T-cell subset relationships in thymocyte development

1991 • 42 citations

Thymic pathology in primary and secondary immunodeficiencies

1992 • 41 citations