Scaffold-associated regions: cis-acting determinants of chromatin structural loops and functional domains

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1984 • 1,088 citations

The structure of an oligo(dA)·oligo(dT) tract and its biological implications

1987 • 975 citations

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1986 • 922 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

DNA topoisomerase II is required at the time of mitosis in yeast

1985 • 747 citations

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

1991 • 722 citations

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1987 • 691 citations

CpG islands as gene markers in the vertebrate nucleus

1987 • 687 citations

DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication.

1984 • 685 citations

A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome

1984 • 674 citations

The A.T-DNA-binding domain of mammalian high mobility group I chromosomal proteins. A novel peptide motif for recognizing DNA structure.

1990 • 674 citations

A bifurcated hydrogen-bonded conformation in the d(A.T) base pairs of the DNA dodecamer d(CGCAAATTTGCG) and its complex with distamycin.

1987 • 671 citations

A position-effect assay for boundaries of higher order chromosomal domains

1991 • 616 citations

A nuclear DNA attachment element mediates elevated and position-independent gene activity

1989 • 597 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

Metaphase chromosome structure

1986 • 538 citations

Assembly and propagation of repressed and derepressed chromosomal states

1985 • 518 citations

Localization of topoisomerase II in mitotic chromosomes.

1985 • 501 citations

Substrates for p34cdc2: In vivo veritas?

1990 • 472 citations

Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization.

1984 • 444 citations

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

1987 • 440 citations

A glimpse at chromosomal order

1987 • 423 citations

Biological Significance of Unwinding Capability of Nuclear Matrix-Associating DNAs

1992 • 407 citations

Higher order metaphase chromosome structure: Evidence for metalloprotein interactions

1982 • 398 citations

Chromosome assembly in vitro: Topoisomerase II is required for condensation

1991 • 382 citations

Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes

1987 • 349 citations

THE NUCLEUS: STRUCTURE, FUNCTION, AND DYNAMICS

1987 • 333 citations

Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions.

1989 • 317 citations

The organisation of chromatin loops: characterization of a scaffold attachment site

1986 • 308 citations

The beta-globin dominant control region: hypersensitive site 2.

1990 • 295 citations

Tissue specific and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice.

1990 • 289 citations

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes.

1989 • 280 citations

The chicken lysozyme 5' matrix attachment region increases transcription from a heterologous promoter in heterologous cells and dampens position effects on the expression of transfected genes.

1990 • 276 citations

Alternative processing of mRNAs encoding mammalian chromosomal high-mobility-group proteins HMG-I and HMG-Y.

1989 • 241 citations

The metaphase scaffold is helically folded: Sister chromatids have predominantly opposite helical handedness

1988 • 232 citations

Developmental Regulation of Two 5 S Ribosomal RNA Genes

1988 • 229 citations

Nuclear scaffold attachment sites in the human globin gene complexes.

1988 • 225 citations

Phosphorylation of DNA topoisomerase II by casein kinase II: modulation of eukaryotic topoisomerase II activity in vitro.

1985 • 214 citations

A matrix/scaffold attachment region binding protein: Identification, purification, and mode of binding

1991 • 205 citations

Protein motifs that recognize structural features of DNA

1991 • 200 citations

Curvature of mouse satellite DNA and condensation of heterochromatin

1987 • 192 citations

Nucleosomes: regulators of transcription

1990 • 186 citations

In vivo topoisomerase II cleavage of the Drosophila histone and satellite III repeats: DNA sequence and structural characteristics.

1992 • 181 citations

Chromatin structure of transcriptionally competent and repressed genes.

1990 • 178 citations

Scaffold-attached regions from the human interferon .beta. domain can be used to enhance the stable expression of genes under the control of various promoters

1991 • 177 citations

Irresistible force meets immovable object: Transcription and the nucleosome

1991 • 175 citations

Highly preferential nucleation of histone H1 assembly on scaffold-associated regions

1989 • 165 citations

Specific inhibition of DNA Binding to nuclear scaffolds and histone H1 by distamycin

1989 • 137 citations

Hierarchical binding of DNA fragments derived from scaffold-attached regions: correlation of properties in vitro and function in vivo

1990 • 131 citations

Immunoglobulin κ gene expression after stable integration

1989 • 120 citations

Boundary functions in the control of gene expression

1991 • 118 citations

A DNA binding protein that recognizes oligo(dA).oligo(dT) tracts.

1989 • 117 citations

In vivo phosphorylation of the 170-kDa form of eukaryotic DNA topoisomerase II

1989 • 112 citations

Protein D1 preferentially binds A + T-rich DNA in vitro and is a component of Drosophila melanogaster nucleosomes containing A + T-rich satellite DNA.

1982 • 111 citations

Developmental Regulation of Topoisomerase II Sites and DNase I-Hypersensitive Sites in the Chicken β-Globin Locus

1990 • 108 citations

Site-independent expression of the chicken βA-globin gene in transgenic mice

1990 • 106 citations

Presence of histone H1 on an active Balbiani ring gene

1990 • 101 citations

Immunoglobulin κ gene expression after stable integration

1989 • 81 citations

Purification and characterization of type II DNA topoisomerase from mouse FM3A cells: phosphorylation of topoisomerase II and modification of its activity

1990 • 70 citations

Bent DNA is a structural feature of scaffold-attached regions in Drosophila melanogaster interphase nuclei

1989 • 70 citations

Developmental regulation of topoisomerase II sites and DNase I-hypersensitive sites in the chicken beta-globin locus.

1990 • 66 citations

Chromosomal Loop Organization in Eukaryotic Genomes

1990 • 59 citations

Chromatin fine structure of the histone gene complex ofDrosophila melanogaster

1983 • 54 citations

The arrangement of H5 molecules in extended and condensed chicken erythrocyte chromatin.

1985 • 48 citations

Influence of DNA-binding drugs on chromatin condensation

1986 • 40 citations

A nuclear matrix protein binds very tightly to DNA in the avian .beta.-globin gene enhancer

1990 • 33 citations

Replication origins, factors and attachment sites

1991 • 24 citations

DNA topoisomerases

1989 • 22 citations

Effect of Distamycin A on Chinese hamster chromosomes

1977 • 9 citations