Biological Significance of Unwinding Capability of Nuclear Matrix-Associating DNAs

Supercoiling of the DNA template during transcription.

1987 • 1,909 citations

DNA TOPOISOMERASES

1985 • 1,524 citations

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1984 • 1,088 citations

DNA Topoisomerases

1981 • 977 citations

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1986 • 922 citations

Transcription generates positively and negatively supercoiled domains in the template

1988 • 742 citations

A position-effect assay for boundaries of higher order chromosomal domains

1991 • 616 citations

A nuclear DNA attachment element mediates elevated and position-independent gene activity

1989 • 597 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

A glimpse at chromosomal order

1987 • 423 citations

Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions.

1989 • 317 citations

Magnesium ion-dependent triple-helix structure formed by homopurine-homopyrimidine sequences in supercoiled plasmid DNA.

1988 • 315 citations

Fluorescent adenosine and cytidine derivatives

1972 • 283 citations

The chicken lysozyme 5' matrix attachment region increases transcription from a heterologous promoter in heterologous cells and dampens position effects on the expression of transfected genes.

1990 • 276 citations

Supercoiling of intracellular DNA can occur in eukaryotic cells

1988 • 263 citations

Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold

1988 • 251 citations

The 87A7 chromomere

1985 • 249 citations

The enhancer of the immunoglobulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements.

1987 • 229 citations

Nuclear scaffold attachment sites in the human globin gene complexes.

1988 • 225 citations

Topoisomerase I interacts with transcribed regions in Drosophila cells

1986 • 210 citations

The ease of DNA unwinding as a determinant of initiation at yeast replication origins

1988 • 193 citations

Scaffold-attached regions from the human interferon .beta. domain can be used to enhance the stable expression of genes under the control of various promoters

1991 • 177 citations

Matrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells.

1988 • 177 citations

New reaction of adenine and cytosine derivatives, potentially useful for nucleic acids modification.

1971 • 171 citations

Chromatin domain surrounding the human interferon-.beta. gene as defined by scaffold-attached regions

1988 • 169 citations

The limits of the DNase I-sensitive domain of the human apolipoprotein B gene coincide with the locations of chromosomal anchorage loops and define the 5′ and 3′ boundaries of the gene

1989 • 139 citations

Torsional stress stabilizes extended base unpairing in suppressor sites flanking immunoglobulin heavy chain enhancer

1990 • 135 citations

Formation of nucleosomes on positively supercoiled DNA.

1991 • 133 citations

Hierarchical binding of DNA fragments derived from scaffold-attached regions: correlation of properties in vitro and function in vivo

1990 • 131 citations

Advantages of firefly luciferase as a reporter gene: Application to the interleukin-2 gene promoter

1989 • 112 citations

Poising chromatin for transcription

1987 • 103 citations

Chromatin structure of the chicken lysozyme gene domain as determined by chromatin fractionation and micrococcal nuclease digestion

1986 • 74 citations

In vitro transcription of eukaryotic genes is affected differently by the degree of DNA supercoiling.

1988 • 73 citations

Negative supercoiling of DNA facilitates an interaction between transcription factor IID and the fibroin gene promoter.

1991 • 72 citations

Bent DNA is a structural feature of scaffold-attached regions in Drosophila melanogaster interphase nuclei

1989 • 70 citations

A non-curved chicken lysozyme 5' matrix attachment site is 3' followed by a strongly curved DNA sequence

1990 • 64 citations

Association of DNA with Nuclear Matrix

1990 • 46 citations

The nuclear scaffold exhibits DNA-binding sites selective for supercoiled DNA.

1988 • 45 citations

DNA regions associated with the nuclear matrix of Ehrlich ascites cells expose single‐stranded sites after deproteinization

1985 • 25 citations

Supercoiled DNA: Biological significance

1987 • 19 citations