Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization.

DNA gyrase: an enzyme that introduces superhelical turns into DNA.

1976 • 1,175 citations

DNA Topoisomerases

1981 • 977 citations

Interaction between DNA and an Escherichia coli protein ω

1971 • 749 citations

Isolation of an E. coli Strain with a Mutation affecting DNA Polymerase

1969 • 749 citations

Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.

1976 • 719 citations

DNA Gyrase and the Supercoiling of DNA

1980 • 713 citations

Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis.

1975 • 538 citations

Escherichia coli DNA topoisomerase I mutants have compensatory mutations in DNA gyrase genes

1982 • 450 citations

Escherichia coli DNA topoisomerase I mutants: Increased supercoiling is corrected by mutations near gyrase genes

1982 • 376 citations

A homogeneous type II DNA topoisomerase from HeLa cell nuclei.

1981 • 361 citations

An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication

1972 • 332 citations

Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe

1981 • 309 citations

ATP-dependent DNA topoisomerase from D. melanogaster reversibly catenates duplex DNA rings

1980 • 292 citations

Mutations in the gene coding for Escherichia coli DNA topoisomerase I affect transcription and transposition.

1981 • 284 citations

T4 DNA topoisomerase: a new ATP-dependent enzyme essential for initiation of T4 bacteriophage DNA replication

1979 • 262 citations

GENETIC MAPPING IN SCHIZOSACCHAROMYCES POMBE BY MITOTIC AND MEIOTIC ANALYSIS AND INDUCED HAPLOIDIZATION

1977 • 246 citations

Novel topologically knotted DNA from bacteriophage P4 capsids: studies with DNA topoisomerases

1981 • 231 citations

Site-specific relaxation and recombination by the Tn3 resolvase: Recognition of the DNA path between oriented res sites

1983 • 186 citations

Nicking-closing activity associated with bacteriophage lambda int gene product.

1979 • 182 citations

Chapter 11 Cell Cycle Analysis

1975 • 167 citations

Cold-sensitive nuclear division arrest mutants of the fission yeast Schizosaccharomyces pombe

1983 • 165 citations

Yeast DNA topoisomerase II. An ATP-dependent type II topoisomerase that catalyzes the catenation, decatenation, unknotting, and relaxation of double-stranded DNA rings.

1982 • 164 citations

DNA synthesis in the fission yeast Schizosaccharomyces pombe

1970 • 139 citations

Identification of Saccharomyces cerevisiae mutants deficient in DNA topoisomerase I activity.

1984 • 137 citations

Sequential alterations in the nuclear chromatin region during mitosis of the fission yeast Schizosa Ccharomyces Pombe-: Video fluorescence microscopy of synchronously growing wild-type and cold-sensitive cdc mutants by using a dna-binding fluorescent probe

1981 • 135 citations

In vitro catenation and decatenation of DNA and a novel eucaryotic ATP-dependent topoisomerase

1980 • 134 citations

Isolation and Mapping of Polynucleotide Phosphorylase Mutants of Escherichia coli

1969 • 105 citations

DNA topoisomerases

1980 • 91 citations

Isolation and Partial Characterisation of the Relaxation Protein from Nuclei of Cultured Mouse and Human Cells

1975 • 77 citations

Identification and localization of a gene that specifies production of Escherichia coli DNA topoisomerase I.

1981 • 66 citations

Cell cycle analysis.

1975 • 20 citations