Immunoglobulin κ gene expression after stable integration

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Genetic transformation of mouse embryos by microinjection of purified DNA.

1980 • 1,428 citations

GERM-LINE TRANSFORMATION OF MICE

1986 • 1,165 citations

Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.

1985 • 1,052 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

Introns increase transcriptional efficiency in transgenic mice.

1988 • 733 citations

[20] Isolation of RNA using guanidinium salts

1987 • 614 citations

Transgenic Animals

1988 • 473 citations

Erythroid-specific expression of human beta-globin genes in transgenic mice.

1985 • 436 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

[45] The use of intensifying screens or organic scintillators for visualizing radioactive molecules resolved by gel electrophoresis

1980 • 367 citations

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice.

1989 • 365 citations

Diversity of Alpha-Fetoprotein Gene Expression in Mice Is Generated by a Combination of Separate Enhancer Elements

1987 • 315 citations

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

1986 • 308 citations

Allelic Exclusion in Transgenic Mice That Express the Membrane form of Immunoglobulin μ

1987 • 293 citations

Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line

1985 • 244 citations

Transgenic mice

1985 • 243 citations

The enhancer of the immunoglobulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements.

1987 • 229 citations

The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region.

1989 • 213 citations

Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice

1983 • 202 citations

Two regulatory elements for immunoglobulin kappa light chain gene expression.

1984 • 197 citations

Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in κ transgenic mice

1984 • 184 citations

A transgenic immunoglobulin Mu gene prevents rearrangement of endogenous genes

1985 • 169 citations

Fine mapping of an immunoglobulin gene activator.

1984 • 144 citations

An immunoglobulin promoter displays cell-type specificity independently of the enhancer

1985 • 144 citations

Transgenic Mice with Immunoglobulin Genes

1987 • 137 citations

Immunoglobulin κ gene expression after stable integration

1989 • 120 citations

A developmental-specific factor binds to suppressor sites flanking the immunoglobulin heavy-chain enhancer.

1989 • 116 citations

High expression of cloned immunoglobulin k gene in transgenic mice is restricted to B lymphocytes

1984 • 114 citations

Negative regulation contributes to tissue specificity of the immunoglobulin heavy-chain enhancer.

1987 • 113 citations

Somatic hypermutation of an immunoglobulin transgene in K transgenic mice

1987 • 110 citations

Use of Gene Transfer to Increase Animal Growth

1985 • 96 citations

Contribution of Promoter to Tissue-Specific Expression of the Mouse Immunoglobulin Kappa Gene

1985 • 76 citations

Differential requirements for cell-specific elastase I enhancer domains in transfected cells and transgenic mice.

1989 • 72 citations

Concentrated, digestible DNA after hydroxylapatite chromatography with cetylpyridinium bromide precipitation

1983 • 70 citations

Expression of immunoglobulin delta chain causes allelic exclusion in transgenic mice

1987 • 70 citations