HYPOXIC-ISCHEMIC ENCEPHALOPATHY

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1993 • 3,465 citations

Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders

1994 • 2,668 citations

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

1994 • 2,646 citations

Blockade of NMDA Receptors and Apoptotic Neurodegeneration in the Developing Brain

1999 • 2,023 citations

Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

1987 • 1,821 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Calcium Fluxes, Calcium Antagonists, and Calcium-Related Pathology in Brain Ischemia, Hypoglycemia, and Spreading Depression: A Unifying Hypothesis

1989 • 1,237 citations

Intravenous Administration of Human Umbilical Cord Blood Reduces Behavioral Deficits After Stroke in Rats

2001 • 1,230 citations

NMDA-dependent superoxide production and neurotoxicity

1993 • 1,188 citations

Adverse effects of prolonged hyperventilation in patients with severe head injury: a randomized clinical trial

1991 • 1,170 citations

Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress

2001 • 1,009 citations

NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices

1989 • 912 citations

Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death

1984 • 893 citations

Assessing the outcome of pediatric intensive care

1992 • 844 citations

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis

1995 • 834 citations

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.

1990 • 787 citations

Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger

1992 • 656 citations

Cerebral hyperglycolysis following severe traumatic brain injury in humans: a positron emission tomography study

1997 • 637 citations

Ischemia-induced neuronal apoptosis

1996 • 600 citations

Brain Lactic Acidosis and Ischemic Cell Damage: 1. Biochemistry and Neurophysiology

1981 • 585 citations

Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia

2001 • 568 citations

Cerebral Blood Flow and Cerebral Oxygen Consumption During Hypothermia

1954 • 560 citations

Delayed (“Secondary”) Cerebral Energy Failure after Acute Hypoxia-Ischemia in the Newborn Piglet: Continuous 48-Hour Studies by Phosphorus Magnetic Resonance Spectroscopy

1994 • 548 citations

Free Radicals and Brain Damage

1993 • 527 citations

Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues.

1989 • 518 citations

BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway.

2000 • 517 citations

Reperfusion injury and its pharmacologic modification.

1989 • 509 citations

Predicting the outcome from hypoxic-ischemic coma

1986 • 496 citations

Temporal Profile of in situ DNA Fragmentation after Transient Middle Cerebral Artery Occlusion in the Rat

1995 • 477 citations

Outcome of Out-of-Hospital Cardiac Arrest in New York City

1994 • 472 citations

Upregulation of bax protein levels in neurons following cerebral ischemia

1995 • 440 citations

A mechanism for glucocorticoid toxicity in the hippocampus: increased neuronal vulnerability to metabolic insults

1985 • 406 citations

Brain Lactic Acidosis and Ischemic Cell Damage: 2. Histopathology

1981 • 396 citations

Pediatric Cardiopulmonary Resuscitation: A Collective Review

1999 • 375 citations

Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury

1989 • 368 citations

Mild Cerebral Hypothermia during and after Cardiac Arrest Improves Neurologic Outcome in Dogs

1990 • 363 citations

Apoptosis and necrosis. Basic types and mechanisms of cell death.

1993 • 353 citations

The Influence of Mild Body and Brain Hypothermia on Ischemic Brain Damage

1990 • 351 citations

A Prospective, Population-Based Study of the Demographics, Epidemiology, Management, and Outcome of Out-of-Hospital Pediatric Cardiopulmonary Arrest

1999 • 348 citations

Non-NMDA and NMDA receptor-mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: Further evidence for an apoptosis-necrosis continuum

1997 • 339 citations

Early Neurodegeneration after Hypoxia-Ischemia in Neonatal Rat Is Necrosis while Delayed Neuronal Death Is Apoptosis

2001 • 336 citations

Cerebral blood flow and metabolism in severely head-injured children

1989 • 335 citations

Excitotoxic neuronal death in the immature brain is an apoptosis-necrosis morphological continuum

1997 • 333 citations

Selfotel in Acute Ischemic Stroke

2000 • 329 citations

Improved Cerebral Resuscitation From Cardiac Arrest in Dogs With Mild Hypothermia Plus Blood Flow Promotion

1996 • 319 citations

Cardiopulmonary cerebral resuscitation using emergency cardiopulmonary bypass, coronary reperfusion therapy and mild hypothermia in patients with cardiac arrest outside the hospital

2000 • 309 citations

Adenosine and Brain Ischemia

1995 • 298 citations

Expression of bcl-2 From a Defective Herpes Simplex Virus–1 Vector Limits Neuronal Death in Focal Cerebral Ischemia

1995 • 297 citations

Serum S-100 and Neuron-Specific Enolase for Prediction of Regaining Consciousness After Global Cerebral Ischemia

1998 • 293 citations

INCIDENCE OF HYPOGLYCEMIA IN NEWBORN INFANTS CLASSIFIED BY BIRTH WEIGHT AND GESTATIONAL AGE

1971 • 280 citations

The stress protein response in cultured neurons: Characterization and evidence for a protective role in excitotoxicity

1991 • 279 citations

Increases in Bcl‐2 and cleavage of caspase‐1 and caspase‐3 in human brain after head injury

1999 • 278 citations

Influence of Acidosis on Lipid Peroxidation in Brain Tissues in vitro

1985 • 278 citations

Delayed Neurodegeneration in Neonatal Rat Thalamus after Hypoxia–Ischemia Is Apoptosis

2001 • 277 citations

Mechanism of Arachidonic Acid Liberation During Ischemia in Gerbil Cerebral Cortex

1987 • 271 citations

Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: evidence against programmed cell death

1992 • 270 citations

N‐methyl‐<scp>D</scp>‐aspartate antagonists: Ready for clinical trial in brain ischemia?

1989 • 270 citations

Transient hyperthermia protects against subsequent forebrain ischemic cell damage in the rat

1989 • 270 citations

Neuropsychological Sequelae of Cardiac Arrest

1993 • 263 citations

Predictive value of Glasgow coma score for awakening after out-of-hospital cardiac arrest. Cerebral Resuscitation Study Group of the Belgian Society for Intensive Care.

1988 • 259 citations

Nimodipine Improves Outcome when Given after Complete Cerebral Ischemia in Primates

1985 • 256 citations

Global Ischemia in Dogs: Intracranial Pressures, Brain Blood Flow and Metabolism

1975 • 254 citations

Outcome Model of Asphyxial Cardiac Arrest in Rats

1995 • 245 citations

The N-methyl-D-aspartate antagonist, MK-801, fails to protect against neuronal damage caused by transient, severe forebrain ischemia in adult rats

1991 • 239 citations

Hydrogen Ions Kill Brain at Concentrations Reached in Ischemia

1987 • 237 citations

Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats.

1989 • 237 citations

Motor-sensory and visual behavior after hemispherectomy in newborn and mature rats

1970 • 231 citations

Excitotoxicity, free radicals, and cell membrane changes

1994 • 228 citations

Beneficial effect of mild hypothermia and detrimental effect of deep hypothermia after cardiac arrest in dogs.

1992 • 228 citations

Influence of hypothermia, barbiturate therapy, and intracranial pressure monitoring on morbidity and mortality after near-drowning

1986 • 226 citations

Neuropathological Findings in the Brain of Karen Ann Quinlan -- The Role of the Thalamus in the Persistent Vegetative State

1994 • 218 citations

Therapeutic Potential of Neurotrophic Factors and Neural Stem Cells Against Ischemic Brain Injury

2000 • 217 citations

Expression of bcl‐2 inhibits necrotic neural cell death

1995 • 216 citations

Cerebral blood flow and metabolism in severely head-injured children

1989 • 212 citations

Cerebral resuscitation after cardiac arrest: a review.

1986 • 210 citations

The temporal profile of 72-kDa heat-shock protein expression following global ischemia

1991 • 206 citations

CEREBRAL METABOLISM IN ISCHAEMIA: NEUROCHEMICAL BASIS FOR THERAPY

1985 • 206 citations

The Threshold and Neuropathology of Cerebral "Anoxic-Ischemic" Cell Change

1973 • 200 citations

Increase in bcl-2 oncoprotein and the tolerance to ischemia-induced neuronal death in the gerbil hippocampus

1994 • 197 citations

Inhibition of caspase activity induces a switch from apoptosis to necrosis

1998 • 189 citations

Effect of moderate hypothermia on lipid peroxidation in canine brain tissue after cardiac arrest and resuscitation.

1994 • 189 citations

Cardiopulmonary-cerebral resuscitation with 100% oxygen exacerbates neurological dysfunction following nine minutes of normothermic cardiac arrest in dogs

1994 • 182 citations

A randomized, blinded trial of high-dose epinephrine versus standard-dose epinephrine in a swine model of pediatric asphyxial cardiac arrest

1996 • 180 citations

Protective effect of α-tocopherol on ischemic neuronal damage in the gerbil hippocampus

1990 • 180 citations

Mechanisms of oxidant injury of cells

1991 • 177 citations

Emergency cardiopulmonary bypass for resuscitation from prolonged cardiac arrest

1990 • 174 citations

Polyphosphoinositides as a Probable Source of Brain Free Fatty Acids Accumulated at the Onset of Ischemia

1986 • 172 citations

Very Early Nimodipine Use in Stroke (VENUS)

2001 • 172 citations

Chronic Dexamethasone Pretreatment Aggravates Ischemic Neuronal Necrosis

1986 • 172 citations

bcl-2 is expressed in neurons that survive focal ischemia in the rat

1995 • 169 citations

Early prediction of individual outcome after cardiopulmonary resuscitation

1993 • 168 citations

Effect of hypothermia and cardiac arrest on outcome of near-drowning accidents in children

1990 • 163 citations

Global brain ischemia: a reproducible monkey model.

1977 • 161 citations

Age-related thermoregulatory differences during core cooling in humans

2000 • 160 citations

Altered Mitochondrial Respiration in Selectively Vulnerable Brain Subregions Following Transient Forebrain Ischemia in the Rat

1987 • 159 citations

Primary sensory and forebrain motor systems in the newborn brain are preferentially damaged by hypoxia-ischemia

1997 • 158 citations

Outcome of children who are apneic and pulseless in the emergency room

1986 • 157 citations

Proton Magnetic Resonance Spectroscopy of the Brain during Acute Hypoxia-Ischemia and Delayed Cerebral Energy Failure in the Newborn Piglet

1997 • 155 citations

N‐Methyl‐D‐Aspartate antagonist reduces stroke size and regional glucose metabolism

1990 • 155 citations

Nerve growth factor protects the neonatal brain against hypoxic–ischemic injury

1996 • 154 citations

Induction of vascular endothelial growth factor and hypoxia-inducible factor-1α by global ischemia in rat brain

2000 • 152 citations

Overexpression of HSP72 after Induction of Experimental Stroke Protects Neurons from Ischemic Damage

2001 • 148 citations

Protective effects of combined superoxide dismutase and deferoxamine on recovery of cerebral blood flow and function after cardiac arrest in dogs.

1987 • 141 citations

Apoptosis After Experimental Stroke: Fact or Fashion?

2000 • 140 citations

High-dose epinephrine improves outcome from pediatric cardiac arrest

1991 • 140 citations

Role of adenosine in regulation of cerebral blood flow: effects of theophylline during normoxia and hypoxia

1987 • 139 citations

Prognostic Value of EEG in Post-Anoxic Coma after Cardiac Arrest

1987 • 139 citations

Prediction of outcome after cardiac arrest

1987 • 136 citations

High dose versus standard dose epinephrine in cardiac arrest — a meta-analysis

2000 • 136 citations

Brain damage and neuroplasticity: Mechanisms of recovery or development?

1985 • 134 citations

Cerebral blood flow and metabolism in man following cardiac arrest.

1978 • 134 citations

Hypothermia and Hyperthermia in Children After Resuscitation From Cardiac Arrest

2000 • 133 citations

Hypoxic encephalopathy after near-drowning studied by quantitative 1H-magnetic resonance spectroscopy.

1996 • 133 citations

Delayed, spontaneous hypothermia reduces neuronal damage after asphyxial cardiac arrest in rats

2000 • 132 citations

Neuropathology of systemic circulatory arrest in adult monkeys

1972 • 125 citations

Asphyxiation versus ventricular fibrillation cardiac arrest in dogs.

1997 • 125 citations

Glucocorticoid treatment does not improve neurological recovery following cardiac arrest. Brain Resuscitation Clinical Trial I Study Group.

1989 • 123 citations

Prostanoids determine the range of cerebral blood flow autoregulation of newborn piglets.

1990 • 117 citations

Does acute hyperventilation provoke cerebral oligaemia in comatose patients after acute head injury?

1989 • 114 citations

Early brain proton magnetic resonance spectroscopy and neonatal neurology related to neurodevelopmental outcome at 1 year in term infants after presumed hypoxic–ischaemic brain injury

1999 • 112 citations

Effect of Mild Hypothermia on Cerebral Energy Metabolism During the Evolution of Hypoxic-Ischemic Brain Damage in the Immature Rat

1996 • 108 citations

Multifocal cerebral blood flow by Xe-CT and global cerebral metabolism after prolonged cardiac arrest in dogs. Reperfusion with open-chest CPR or cardiopulmonary bypass

1992 • 108 citations

Caspase-Activated DNase/DNA Fragmentation Factor 40 Mediates Apoptotic DNA Fragmentation in Transient Cerebral Ischemia and in Neuronal Cultures

2001 • 106 citations

Cerebral Blood Flow and Edema in Perinatal Hypoxic-Ischemic Brain Damage

1990 • 105 citations

Prevention of Reperfusion Injury of the Ischemic Spinal Cord: Use of Recombinant Superoxide Dismutase

1986 • 102 citations

Neuroprotective effects of tetrodotoxin as a Na+ channel modulator and glutamate release inhibitor in cultured rat cerebellar neurons and in gerbil global brain ischemia.

1994 • 102 citations

Long‐term survival and neurologic status after resuscitation from out‐of‐hospital cardiac arrest

1980 • 101 citations

THERAPEUTIC HYPOTHERMIA IN TRAUMATOLOGY

1999 • 101 citations

Recovery of Monkey Brain after Prolonged Ischemia. II. Protein Synthesis and Morphological Alterations

1986 • 98 citations

Prostaglandin I₂, indomethacin, and heparin promote postischemic neuronal recovery in dogs

1982 • 98 citations

Outcome of pediatric resuscitation

1983 • 98 citations

Suspended animation for delayed resuscitation.

1996 • 97 citations

Free radical production and ischemic brain damage: Influence of postischemic oxygen tension

1991 • 97 citations

Brain iron delocalization and lipid peroxidation following cardiac arrest

1986 • 97 citations

The Role of Oxygen Free Radicals in Postasphyxia Cerebral Hypoperfusion in Newborn Lambs

1989 • 96 citations

Indomethacin ameliorates ischemic neuronal damage in the gerbil hippocampal CA1 sector.

1988 • 95 citations

Effect of acidosis and anoxia on iron delocalization from brain homogenates

1992 • 89 citations

Cerebral blood flow in humans following resuscitation from cardiac arrest.

1989 • 89 citations

Cardiorespiratory Arrest and Resuscitation of Children

1984 • 89 citations

Effect of cyclooxygenase and lipoxygenase inhibitors on delayed neuronal death in the gerbil hippocampus.

1989 • 87 citations

Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema.

1988 • 87 citations

Changes in the hippocampus and the cerebellum resulting from hypoxic insults: frequency and distribution

1989 • 84 citations

MR of hypoxic encephalopathy in children after near drowning : Correlation with Quantitative proton MR spectroscopy and clinical outcome

1998 • 84 citations

Local cerebral blood flow following transient cerebral ischemia. I. Onset of impaired reperfusion within the first hour following global ischemia.

1980 • 83 citations

Pharmacologic Properties of PhenylN-tert-Butylnitrone

1999 • 82 citations

Neuroprotective effect of high-dose albumin therapy against global ischemic brain injury in rats

1999 • 80 citations

Effects of Nimodipine on Cerebral Blood Flow and Cerebrospinal Fluid Pressure After Cardiac Arrest

1989 • 79 citations

Therapeutic potential for adenosine receptor activation in ischemic brain injury.

1992 • 79 citations

Intracranial pressure and cerebral perfusion pressure in near-drowning

1985 • 79 citations

The Protective Effect of Ceramide in Immature Rat Brain Hypoxia—Ischemia Involves Up-Regulation of BCL-2 and Reduction of TUNEL-Positive Cells

2001 • 74 citations

Adrenergic agonists during cardiopulmonary resuscitation

1990 • 74 citations

Selective brainstem injury in an asphyxiated newborn

1988 • 74 citations

Prostanoids determine the range of cerebral blood flow autoregulation of newborn piglets.

1990 • 73 citations

Prevention of post-ischemic brain lipid conjugated diene production and neurological injury by hydroxyethyl starch-conjugated deferoxamine

1992 • 72 citations

Induction of cyclooxygenase ii in human synovial microvessel endothelial cells by interleukin‐1

1994 • 72 citations

¹H‐magnetic resonance spectroscopy—determined cerebral lactate and poor neurological outcomes in children with central nervous system disease

1997 • 72 citations

The mechanism of pH-dependent hydrogen peroxide cytotoxicity in vitro

1988 • 71 citations

Postasphyxial Cerebral Survival in Newborn Sheep after Treatment with Oxygen Free Radical Scavengers and a Calcium Antagonist

1987 • 71 citations

Prognostic implications of hyperglycemia and reduced cerebral blood flow in childhood near-drowning

1990 • 70 citations

Antioxidant Tempol Enhances Hypothermic Cerebral Preservation during Prolonged Cardiac Arrest in Dogs

2002 • 70 citations

Cerebral Blood Flow and O2 Metabolism after Asphyxia in Neonatal Lambs

1986 • 69 citations

Indomethacin prevents impaired perfusion of the dogs's brain after global ischemia.

1978 • 67 citations

Prevention of postischemic impairment of microvascular perfusion

1977 • 66 citations

Oxygen Free Radicals in the Genesis of Traumatic and Peritumoral Brain Edema

1989 • 66 citations

Vascular endothelial growth factor upregulation in transient global ischemia induced by cardiac arrest and resuscitation in rat brain

1999 • 62 citations

Intracranial pressure monitoring as a guide to prognosis in the nearly drowned, severely comatose child

1983 • 62 citations

Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia

1991 • 62 citations

Glutamate-mediated selective vulnerability to ischemia is present in organotypic cultures of hippocampus

1990 • 61 citations

Brain Lactate and Neurologic Outcome Following Incomplete Ischemia in Fasted, Nonfasted, and Glucose-loaded Rats

1990 • 60 citations

Intracranial Pressure Monitoring in Severe Pediatric Near-Drowning

1981 • 60 citations

Hypoxic neuronal injury in vitro depends on extracellular glutamine

1988 • 60 citations

Dynamic heterogeneity of cerebral hypoperfusion after prolonged cardiac arrest in dogs measured by the stable xenon/CT technique: a preliminary study

1992 • 59 citations

Free Radicals Enhance Basal Release of D‐[³H]Aspartate from Cerebral Cortical Synaptosomes

1994 • 58 citations

Postischemic Canine Cerebral Blood Flow Appears to Be Determined by Cerebral Metabolic Needs

1990 • 57 citations

Reassessment of Brain Free Fatty Acid Liberation During Global Ischemia and Its Attenuation by Barbiturate Anesthesia

1983 • 56 citations

Amino acid and purine release in rat brain following temporary middle cerebral artery occlusion

1994 • 54 citations

Early Evolution and Recovery from Excitotoxic Injury in the Neonatal Rat Brain: A Study Combining Magnetic Resonance Imaging, Electrical Impedance, and Histology

1994 • 52 citations

Pretreatment with U74006F improves neurologic outcome following complete cerebral ischemia in dogs.

1991 • 52 citations

Role of xanthine dehydrogenase and oxidase in focal cerebral ischemic injury to rat

1991 • 51 citations

Peritoneal cooling for mild cerebral hypothermia after cardiac arrest in dogs

1995 • 50 citations

Differential Expression of Rat Brain Caspase Family Proteins during Development and Aging

2001 • 49 citations

Outcome of resuscitation from bradyarrhythmic or asystolic prehospital cardiac arrest

1984 • 49 citations

Antioxidant-dependent amelioration of brain injury: role of CuZn-superoxide dismutase.

1992 • 48 citations

Apheresis as Therapy for Patients with Severe Sepsis and Multiorgan Dysfunction Syndrome

2001 • 48 citations

Paradoxical Increase in Neuronal DNA Fragmentation after Neuroprotective Free Radical Scavenger Treatment in Experimental Traumatic Brain Injury

2001 • 48 citations

Mechanisms of barbiturate protection.

1980 • 48 citations

Inhibitory Effects of Ebselen on Lipid Peroxidation in Rat Liver Microsomes

1986 • 47 citations

Magnetic resonance spectroscopy in neonatal hypoxic-ischaemic insults

2001 • 46 citations

Oxygen Radicals from Arachidonate Metabolism in Abnormal Vascular Responses

1987 • 46 citations

Late improvements in mobility after acquired brain injuries in children

1997 • 40 citations

Augmentation of postischemic brain damage by severe intermittent hypertension

1980 • 39 citations

Cerebral resuscitation therapy in pediatric near-drowning

1985 • 37 citations

Cost-Effectiveness Analysis of Nimodipine Treatment after Aneurysmal Subarachnoid Hemorrhage and Surgery

1999 • 36 citations

Effects of the AMPA Receptor Antagonist NBQX on Outcome of Newborn Pigs after Asphyxic Cardiac Arrest

1999 • 35 citations

Electron spin resonance measure of brain antioxidant activity during ischemia/reperfusion

1998 • 33 citations

The Role of Adenosine in the Vascular Adaptation of Neonatal Cerebral Blood Flow during Hypotension

1991 • 32 citations

Assessment of free radical-induced damage in brain proteins after ischemia and reperfusion

1992 • 32 citations

Therapeutic window of CA1 neuronal damage defined by an ultrashort-acting barbiturate after brain ischemia in gerbils.

1990 • 31 citations

Cardiopulmonary Resuscitation in Children

1987 • 30 citations

Electroencephalographic Studies after Cardiorespiratory Resuscitation

1962 • 30 citations

Use of brainstem auditory-evoked response testing to assess neurologic outcome following near drowning in children

1992 • 29 citations

Ibuprofen improves survival and neurologic outcome after resuscitation from cardiac arrest

1986 • 28 citations

Adenosine and cerebrovascular hyperemia during insulin-induced hypoglycemia in newborn piglet

1993 • 26 citations

Age-related cerebrovascular response to global ischemia in pigs

1990 • 25 citations

Cyclooxygenase-2 immunoreactivity in the ischemic neonatal human brain. An autopsy study.

2001 • 24 citations

Effects of mannitol on cerebral circulation after transient complete cerebral ischemia in dogs

1986 • 24 citations

Regional differences in the rate of energy impairment after threshold level ischemia for induction of cerebral infarction in gerbils

2000 • 24 citations

Prevention, Recognition, and Treatment of Perinatal Asphyxia

1989 • 22 citations

Calcium-calmodulin binding in ischemic rat neurons after calcium channel blocker therapy.

1990 • 22 citations

Prolonged postischemic hyperventilation reduces acute neuronal damage after 15 min of cardiac arrest in the dog

1992 • 21 citations

Hypoxic-Ischemic Tolerance Induced by Hyperthermic Pretreatment in Newborn Rats

2000 • 21 citations

Brain Mitochondrial DNA Is Not Damaged by Prolonged Cardiac Arrest or Reperfusion

1992 • 20 citations

A Reappraisal of Mouth-to-Mouth Ventilation During Bystander-Initiated Cardiopulmonary Resuscitation: A Statement for Healthcare Professionals From the Ventilation Working Group of the Basic Life Support and Pediatric Life Support Subcommittees, American Heart Association

1997 • 20 citations

Developmental aspects of NMDA receptor agonists and antagonists in the central nervous system.

1994 • 19 citations

Polyethylene glycol-conjugated superoxide dismutase fails to blunt postischemic reactive hyperemia

1991 • 16 citations

USE OF HUMAN SERUM ALBUMIN IN CEREBRAL EDEMA FOLLOWING CARDIAC ARREST

1951 • 15 citations

Beagle pup model of perinatal asphyxia: nimodipine studies.

1987 • 15 citations

Regional Expression of Heat Shock Protein 72 MRNA Following Mild and Severe Hypoxia in Neonatal Piglet Brain

1999 • 11 citations

Effects of L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1- benzopyran-6yl-hydrogen phosphate] potassium salt on cerebral energy state and consciousness recovery following transient forebrain ischemia in gerbils.

1994 • 11 citations

Cerebrovascular effects of prolonged hypocarbia and hypercarbia after experimental global ischemia in cats

1985 • 11 citations

Glutathione mobilization during cerebral ischemia and reperfusion in the rat

1992 • 9 citations

Collaborative randomized clinical study of cardiopulmonary-cerebral resuscitation

1981 • 8 citations

Risk monitoring of randomized trials in emergency medicine: Experience of the Brain Resuscitation Clinical Trial II

1991 • 5 citations

Albumin therapy for brain swelling in cardiac arrest: a proposal.

1979 • 3 citations

Future directions for resuscitation research: introduction

1996 • 2 citations