Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

A Flexible System of Enzymatic Analysis

1972 • 4,133 citations

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

A new model of bilateral hemispheric ischemia in the unanesthetized rat.

1979 • 1,934 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

A comparison of three methods of glycogen measurement in tissues

1974 • 755 citations

Insulin effects on monovalent cation transport and Na-K-ATPase activity

1978 • 692 citations

OPTIMAL FREEZING CONDITIONS FOR CEREBRAL METABOLITES IN RATS

1973 • 633 citations

Cerebral Blood Flow and Cerebral Oxygen Consumption During Hypothermia

1954 • 560 citations

Local modulation of adrenergic neuroeffector interaction in the blood vessel well.

1981 • 417 citations

Selective neuron loss after cerebral ischemia in the rat: Possible role of transmitter glutamate

2009 • 305 citations

THE EFFECT OF INDUCED HYPOTHERMIA UPON OXYGEN CONSUMPTION IN THE RAT BRAIN

1975 • 268 citations

Substantia nigra lesion protects against ischemic damage in the striatum

1987 • 267 citations

The Effects of Anesthesia and Hypothermia on Canine Cerebral ATP and Lactate during Anoxia Produced by Decapitation

1970 • 237 citations

EXCITATORY AMINOACID ANTAGONISTS PROVIDE A THERAPEUTIC APPROACH TO NEUROLOGICAL DISORDERS

1985 • 217 citations

Lesions to Schaffer collaterals prevent ischemic death of CA1 pyramidal cells

1986 • 193 citations

The effect of profound hypothermia on preservation of cerebral ATP content during circulatory arrest

1968 • 183 citations

Cerebral Protective Effect of Low-Grade Hypothermia

1981 • 174 citations

Role of dopamine in ischemic striatal injury

1987 • 154 citations

Deterimental effect of prolonged hypothermia in cats and monkeys with and without regional cerebral ischemia.

1979 • 123 citations

Failure of prolonged hypocapnia, hypothermia, or hypertension to favorably alter acute stroke in primates.

1977 • 111 citations

The Use of Hypothermia in Surgical Treatment of Cerebral Vascular Lesions

1955 • 111 citations

PROTECTIVE EFFECTS OF HYPOTHERMIA AGAINST PATHOLOGICAL PROCESSES OF THE NERVOUS SYSTEM*

1959 • 110 citations

ENZYMES OF ENERGY-CONVERTING SYSTEMS IN INDIVIDUAL MAMMALIAN NERVE CELL BODIES

1973 • 96 citations

Failure of nimodipine to prevent ischemic neuronal damage in rats.

1987 • 95 citations

The effect of graded hypothermia on hypoxic-ischemic brain damage: a neuropathologic study in the neonatal rat.

1983 • 89 citations

Effects of hypothermia on the cat brain-stem auditory evoked response

1984 • 81 citations

The protective effect of hypothermia in cerebral ischemia: experimental and clinical application by selective brain cooling in the human.

1962 • 79 citations

Cerebral ischemia produced by four-vessel occlusion in the rat: a quantitative evaluation of cerebral blood flow.

1982 • 72 citations

Hypothermia and cerebral vascular lesions. II. Experimental middle cerebral artery interruption followed by induction of hypothermia.

1957 • 69 citations

Temporary Circulatory Occlusion to the Brain of the Hypothermic Dog

1956 • 68 citations

Early correction of congenital heart disease with surface-induced deep hypothermia and circulatory arrest

1973 • 65 citations

ACID-BASE BALANCE OF THE BLOOD IN DOGS AT REDUCED BODY TEMPERATURE

1954 • 63 citations

Effects of Cerebral Ischemia in Various Strains of Rats.

1965 • 62 citations

Alteration of the turnover of dopamine and 5-hydroxytryptamine in rat brain associated with hypothermia

1986 • 62 citations

Hypothermia and Cerebral Vascular Lesions

1957 • 62 citations

Protective Effects of Combinations of Hypothermia and Barbiturates in Cerebral Hypoxia in the Rat

1978 • 53 citations

HYPOTHERMIA

1959 • 51 citations

STUDY OF BASIC PHYSIOLOGIC CHANGES ASSOCIATED WITH HYPOTHERMIA

1955 • 44 citations

Hypothermia-induced reduction in the permeation of radiolabelled tracer substances across the blood-brain barrier

1983 • 44 citations

Models for studying long-term recovery following forebrain ischemia in the rat. 1. Circulatory and functional effects of 4-vessel occlusion

1984 • 43 citations

Moderate cooling depresses the accumulation and the release of newly synthesized catecholamines in isolated canine saphenous veins

1985 • 38 citations

Graded focal cerebral ischemia in the rat by unilateral carotid artery occlusion and elevated intracranial pressure: hemodynamic and biochemical characterization.

1985 • 36 citations

Effect of Prostaglandin E₁ on Plasma Free Fatty Acids and Blood Glucose in the Dog Prostaglandin and related factors 51

1966 • 36 citations

Central nervous system tolerance to cardiac arrest during profound hypothermia

1975 • 35 citations

The nicotine-induced changes in striatal dopamine metabolism of mice depend on body temperature

1986 • 33 citations

Tolerance of anoxia of the dog's brain at various temperatures.

1961 • 32 citations

Influence of hypothermia on intracellular pH during anoxia

1982 • 26 citations

Changes during ischaemia in extracellular potassium ion concentration of the brain under nitrous oxide or hexobarbital-sodium anaesthesia and moderate hypothermia.

1986 • 21 citations

Selective local hypothermia in neurosurgery.

1961 • 19 citations

Mitochondrial redox responses to cerebral ischaemia produced by four-vessel occlusion in the rat

1985 • 14 citations