Negative Regulation by HLA-DO of MHC Class II-Restricted Antigen Processing

Two populations of Ia-like molecules on a human B cell line.

1980 • 1,112 citations

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1993 • 828 citations

Assembly, Transport, and Function of MHC Class II Molecules

1994 • 791 citations

T Cell-Dependent B Cell Activation

1993 • 727 citations

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

1995 • 684 citations

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

1991 • 663 citations

Mediation by HLA-DM of dissociation of peptides from HLA-DR

1995 • 555 citations

REGULATION OF MHC CLASS II GENES: Lessons from a Disease

1996 • 488 citations

Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus.

1994 • 447 citations

Isolation and characterization of the intracellular MHC class II compartment

1994 • 426 citations

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

1992 • 380 citations

Invariant Chain Structure and MHC Class II Function

1996 • 374 citations

DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.

1985 • 340 citations

Enhanced Dissociation of HLA-DR-Bound Peptides in the Presence of HLA-DM

1996 • 327 citations

Article

1995 • 325 citations

Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

1994 • 318 citations

How MHC Class II Molecules Acquire Peptide Cargo: Biosynthesis and Trafficking through the Endocytic Pathway

1995 • 280 citations

The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation

1997 • 274 citations

Class II transactivator regulates the expression of multiple genes involved in antigen presentation.

1995 • 267 citations

Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells

1994 • 247 citations

Separation of subcellular compartments containing distinct functional forms of MHC class II.

1994 • 221 citations

Invariant Chain Peptides in Most HLA-DR Molecules of an Antigen-Processing Mutant

1992 • 218 citations

HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules

1996 • 206 citations

HLA-DM Acts as a Molecular Chaperone and Rescues Empty HLA-DR Molecules at Lysosomal pH

1997 • 199 citations

Structural model of HLA-DR1 restricted T cell antigen recognition

1988 • 172 citations

HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport.

1996 • 161 citations

The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions.

1985 • 149 citations

Association Between HLA-DM and HLA-DR In Vivo

1996 • 149 citations

A novel class II MHC molecule with unusual tissue distribution

1991 • 126 citations

Two subsets of epithelial cells in the thymic medulla.

1992 • 116 citations

Monoclonal Antibody to HLA-A3

1982 • 115 citations

The two novel MHC class II transactivators RFX5 and CIITA both control expression of HLA-DM genes

1995 • 106 citations

Assembly, Peptide Loading, and Transport of MHC Class I Molecules in a Calnexin-negative Cell Line

1995 • 82 citations

Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes

1995 • 73 citations

HLA-DO is an intracellular class II molecule with distinctive thymic expression

1997 • 73 citations

Human helper T-cell clones that recognize different influenza hemagglutinin determinants are restricted by different HLA-D region epitopes

1984 • 55 citations

Multiple mechanisms regulate the expression of murine immune response genes

1985 • 46 citations

Uncoordinate induction and differential regulation of hla class‐I and class‐II expression by γ‐interferon in differentiating human neuroblastoma cells

1993 • 37 citations

Trafficking of major histocompatibility complex class II molecules through intracellular compartments containing HLA-DM

1996 • 24 citations