DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

1977 • 2,408 citations

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

High-Efficiency Cloning of Full-Length cDNA

1982 • 1,309 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

Plasmid screening at high colony density

1980 • 1,100 citations

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

1983 • 933 citations

The evolution of genes: the chicken preproinsulin gene

1980 • 725 citations

T Cell Subsets and the Recognition of MHC Class

1983 • 702 citations

[15] Detection of specific RNAs or specific fragments of DNA by fractionation in gels and transfer to diazobenzyloxymethyl paper

1979 • 587 citations

Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.

1984 • 579 citations

Histocompatibility Testing 1984

1985 • 535 citations

Structure, Sequence and Polymorphism in the HLA‐D Region

1985 • 302 citations

The structure of a mutant H–2 gene suggests that the generation of polymorphism in H–2 genes may occur by gene conversion-like events

1983 • 277 citations

Complete sequence of an HLA-dR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.

1983 • 271 citations

Isotypic and allotypic variation of human class II histocompatibility antigen α-chain genes

1984 • 261 citations

Gamma ray-induced loss of expression of HLA and glyoxalase I alleles in lymphoblastoid cells.

1980 • 257 citations

[60] Computer analysis of nucleic acids and proteins

1980 • 238 citations

Mutations and selection in the generation of class II histocompatibility antigen polymorphism.

1984 • 232 citations

Human B cell variants immunoselected against a single Ia antigen subset have lost expression of several Ia antigen subsets.

1983 • 205 citations

Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains.

1984 • 190 citations

Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased expression of class II antigens

1984 • 187 citations

Nucleotide sequence of mutant I-Aβbm12 gene is evidence for genetic exchange between mouse immune response genes

1984 • 178 citations

Exon-intron organization and complete nucleotide sequence of a human major histocompatibility antigen DC beta gene.

1983 • 162 citations

Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex.

1983 • 161 citations

Sequence of an HLA-DR α-chain cDNA clone and intron-exon organization of the corresponding gene

1982 • 153 citations

CG dinucleotide clusters in MHC genes and in 5′ demethylated genes

1984 • 146 citations

Characterization of an HLA DR beta pseudogene.

1985 • 138 citations

Allelic polymorphism and complexity of the genes for HLA-DR β-chains—direct analysis by DNA–DNA hybridization

1982 • 133 citations

Unusual evolutionary conservation and frequent DNA segment exchange in class I genes of the major histocompatibility complex.

1983 • 131 citations

The nucleotide sequence of the murine I-E beta b immune response gene: evidence for gene conversion events in class II genes of the major histocompatibility complex.

1984 • 131 citations

Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta.

1984 • 129 citations

Sequence organization of a cloned tDNA1met fragment from xenopus laevis

1978 • 117 citations

Structure and polymorphism of the HLA class II SB light chain genes.

1984 • 115 citations

Genetic mapping of a human class II antigen beta-chain cDNA clone to the SB region of the HLA complex.

1983 • 110 citations

Linkage map of two HLA-SBβ and two HLA-SBα-related genes: an intron in one of the SBβ genes contains a processed pseudogene

1984 • 109 citations

DNA sequence and characterization of human class II major histocompatibility complex beta chains from the DR1 haplotype.

1985 • 109 citations

Structure of Class I Major Histocompatibility Antigens

1983 • 107 citations

Isolation of distinct cDNA clones encoding HLA-DR beta chains by use of an expression assay.

1982 • 105 citations

Molecular organization of the HLA-SB region of the human major histocompatibility complex and evidence for two SB beta-chain genes.

1984 • 91 citations

A minimum of four human class II α-chain genes are encoded in the HLA region of chromosome 6

1983 • 77 citations

Dissection of the D-region of the human major histocompatibility complex by means of induced mutations in a lymphoblastoid cell line

1983 • 76 citations

Allelic polymorphism and transassociation of molecules encoded by the HLA-DQ subregion.

1985 • 68 citations

The Eb beta gene may have acted as the donor gene in a gene conversion-like event generating the Abm 12 beta mutant.

1984 • 62 citations

Ia-negative B-cell variants reveal a coordinate regulation in the transcription of the HLA Class II gene family

1984 • 57 citations

T-Cell clones with similar antigen specificity may be restricted by DR, MT (DC), or SB class II HLA molecules

1984 • 56 citations

Mapping SB in relation to HLA and GL01 using cells from first-cousin marriage offspring

1983 • 48 citations

Localization of the human MHC-linked complement genes between HLA-B and HLA-DR by using HLA mutant cell lines.

1985 • 40 citations

Primary Structure of Human Class II Histocompatibility Antigens 3rd Communication. Amino Acid Sequence Comparison between DR and DC Subclass Antigens Derived from a Lymphoblastoid B Cell Line Homozygous at the HLA Loci (HLA-A3,3; B7,7; Dw2,2; DR2,2; MT1,1; DC1,1;MB1,1)

1983 • 36 citations

Human cytotoxic T-lymphocyte recognition of an HLA-A3 gene product expressed on murine L cells: the only human gene product required on the target cells for lysis is the class I heavy chain.

1985 • 31 citations

Translation and assembly of HLA-DR antigens in Xenopus oocytes injected with mRNA from a human B-cell line.

1982 • 29 citations

Structural relationship of the SB β-chain gene to HLA-D-region genes and murine I-region genes

1984 • 29 citations

Recombination within the HLA-D region. Correlation of molecular genotyping with functional data.

1984 • 24 citations

Structural polymorphism of the DC1 light chains from DR1-, DR2-, and DRw6-positive cell lines

1983 • 22 citations

NH2-terminal sequence of the ? and ? chains of human DC-1 antigen isolated from the JY cell line. Homology with murine I-A molecules

1983 • 16 citations