Resistance of the Human β1-Adrenergic Receptor to Agonist-induced Ubiquitination

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β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

1996 • 1,329 citations

Protein regulation by monoubiquitin

2001 • 1,195 citations

G-protein-coupled receptors and signaling networks: emerging paradigms

2001 • 1,005 citations

Differential Affinities of Visual Arrestin, βArrestin1, and βArrestin2 for G Protein-coupled Receptors Delineate Two Major Classes of Receptors

2000 • 835 citations

Regulation of Receptor Fate by Ubiquitination of Activated β ₂ -Adrenergic Receptor and β-Arrestin

2001 • 807 citations

The endocytic pathway: a mosaic of domains

2001 • 705 citations

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

2002 • 692 citations

UBIQUITIN AND THE CONTROL OF PROTEIN FATE IN THE SECRETORY AND ENDOCYTIC PATHWAYS

1998 • 617 citations

Association of β-Arrestin with G Protein-coupled Receptors during Clathrin-mediated Endocytosis Dictates the Profile of Receptor Resensitization

1999 • 549 citations

Agonist-promoted Ubiquitination of the G Protein-coupled Receptor CXCR4 Mediates Lysosomal Sorting

2001 • 456 citations

Multifaceted roles of β-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling

2003 • 397 citations

The E3 Ubiquitin Ligase AIP4 Mediates Ubiquitination and Sorting of the G Protein-Coupled Receptor CXCR4

2003 • 374 citations

The Interaction of β-Arrestin with the AP-2 Adaptor Is Required for the Clustering of β2-Adrenergic Receptor into Clathrin-coated Pits

2000 • 374 citations

Modulation of Postendocytic Sorting of G Protein-Coupled Receptors

2002 • 322 citations

ERK Plays a Regulatory Role in Induction of LTP by Theta Frequency Stimulation and Its Modulation by β-Adrenergic Receptors

1999 • 318 citations

Altered Beta-adrenergic Receptor Gene Regulation and Signaling in Chronic Heart Failure

2001 • 280 citations

Cytoplasmic Tail Phosphorylation of the α-Factor Receptor Is Required for Its Ubiquitination and Internalization

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Role of endocytosis in mediating downregulation of G-protein-coupled receptors

2001 • 240 citations

Cell-penetrating inhibitors of calpain

1991 • 224 citations

The ins and outs of G protein-coupled receptor trafficking

2003 • 210 citations

A Novel Endocytic Recycling Signal That Distinguishes the Membrane Trafficking of Naturally Occurring Opioid Receptors

2003 • 189 citations

Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway

2003 • 163 citations

Proteasome Involvement in Agonist-induced Down-regulation of μ and δ Opioid Receptors

2001 • 135 citations

Regulation of V2 Vasopressin Receptor Degradation by Agonist-promoted Ubiquitination

2003 • 127 citations

Ubiquitination-independent Trafficking of G Protein-coupled Receptors to Lysosomes

2002 • 124 citations

Regulated ubiquitination of proteins in GPCR-initiated signaling pathways

2003 • 109 citations

Distinct regulation of beta 1- and beta 2-adrenergic receptors in Chinese hamster fibroblasts.

1992 • 106 citations

A proline-rich region of the third intracellular loop imparts phenotypic beta 1-versus beta 2-adrenergic receptor coupling and sequestration

1994 • 98 citations

G protein signaling and the molecular basis of antidepressant action

2003 • 93 citations

Interaction with β-Arrestin Determines the Difference in Internalization Behavior between β1- and β2-Adrenergic Receptors

2000 • 92 citations

Metabolism of Alpha-And Beta-Adrenergic Receptors In Vitro and In Vivo

1987 • 90 citations

β2-Adrenergic Receptor Down-regulation

1999 • 88 citations

Ligand regulation of green fluorescent protein‐tagged forms of the human β₁‐ and β₂‐adrenoceptors; comparisons with the unmodified receptors

2000 • 75 citations

Clathrin Box in G Protein-coupled Receptor Kinase 2

2001 • 64 citations

Differences in endosomal targeting of human β1- and β2-adrenergic receptors following clathrin-mediated endocytosis

2004 • 33 citations

Resistance of the Human β1-Adrenergic Receptor to Agonist-mediated Down-regulation

2003 • 33 citations

Distinct receptor domains determine subtype-specific coupling and desensitization phenotypes for human beta1- and beta2-adrenergic receptors.

1996 • 31 citations

Complexity of Agonist- and Cyclic AMP-Mediated Downregulation of the Human β₁-Adrenergic Receptor: Role of Internalization, Degradation, and mRNA Destabilization

2002 • 22 citations

Differences in desensitization between human β1- and β2-adrenergic receptors stably expressed in transfected hamster cells

1995 • 21 citations

Detection of β-Adrenergic Receptors by Radioligand Binding

2003 • 10 citations