NADPH Oxidase-1 Plays a Crucial Role in Hyperoxia-induced Acute Lung Injury in Mice
Data up to Jan 2025
Total Citations Per Year
Abstract
References (53)
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 • 6,348 citations
NOX enzymes and the biology of reactive oxygen
2004 • 2,940 citations
Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
2005 • 1,727 citations
Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production
1995 • 920 citations
Homologs of gp91 phox : cloning and tissue expression of Nox3, Nox4, and Nox5
2001 • 794 citations
TNF-Induced Activation of the Nox1 NADPH Oxidase and Its Role in the Induction of Necrotic Cell Death
2007 • 504 citations
Two Novel Proteins Activate Superoxide Generation by the NADPH Oxidase NOX1
2003 • 477 citations
Nox1 Is Involved in Angiotensin II–Mediated Hypertension
2005 • 460 citations
Effects of leukotriene B4 in the human lung. Recruitment of neutrophils into the alveolar spaces without a change in protein permeability.
1989 • 342 citations
Isolation and primary culture of murine alveolar type II cells.
1996 • 324 citations
Hypoxia-Dependent Regulation of Nonphagocytic NADPH Oxidase Subunit NOX4 in the Pulmonary Vasculature
2007 • 321 citations
Decreased blood pressure in NOX1‐deficient mice
2005 • 311 citations
Macrophage Signaling and Respiratory Burst
2002 • 280 citations
Oxygen Toxicity in Mouse Lung: Pathways to Cell Death
1998 • 262 citations
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice
2006 • 250 citations
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases
2002 • 247 citations
Dual Oxidase-2 Has an Intrinsic Ca2+-dependent H2O2-generating Activity
2005 • 224 citations
Toll-like receptor 4 deficiency causes pulmonary emphysema
2006 • 215 citations
Reactive Oxygen Species and Extracellular Signal-Regulated Kinase 1/2 Mitogen-Activated Protein Kinase Mediate Hyperoxia-Induced Cell Death in Lung Epithelium
2003 • 200 citations
Hyperoxia-induced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells
2003 • 187 citations
Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species
2004 • 181 citations
Role of Nox4 and Nox2 in Hyperoxia-Induced Reactive Oxygen Species Generation and Migration of Human Lung Endothelial Cells
2008 • 178 citations
Role of NADPH Oxidase in the Mechanism of Lung Neutrophil Sequestration and Microvessel Injury Induced by Gram-Negative Sepsis: Studies in p47phox−/− and gp91phox−/− Mice
2002 • 178 citations
Pathways of cell signaling in hyperoxia
2003 • 178 citations
NADPH Oxidase and ERK Signaling Regulates Hyperoxia-induced Nrf2-ARE Transcriptional Response in Pulmonary Epithelial Cells
2004 • 162 citations
An absence of reactive oxygen species improves the resolution of lung influenza infection
2006 • 158 citations
Roles of Oxidants and Redox Signaling in the Pathogenesis of Acute Respiratory Distress Syndrome
2008 • 155 citations
NADPH Oxidase-1 Plays a Crucial Role in Hyperoxia-induced Acute Lung Injury in Mice
2009 • 143 citations
Src-mediated Tyrosine Phosphorylation of p47 in Hyperoxia-induced Activation of NADPH Oxidase and Generation of Reactive Oxygen Species in Lung Endothelial Cells
2005 • 135 citations
Plasminogen activator inhibitor-1 in acute hyperoxic mouse lung injury.
1996 • 135 citations
NOX1 Deficiency Protects From Aortic Dissection in Response to Angiotensin II
2007 • 133 citations
Hyperoxia-induced signal transduction pathways in pulmonary epithelial cells☆
2007 • 132 citations
Maturational differences in lung NF-κB activation and their role in tolerance to hyperoxia
2004 • 103 citations
Maturational differences in lung NF-κB activation and their role in tolerance to hyperoxia
2004 • 99 citations
Activated Akt Protects the Lung from Oxidant-Induced Injury and Delays Death of Mice
2001 • 97 citations
In vivo exposure to hyperoxia induces DNA damage in a population of alveolar type II epithelial cells
2004 • 79 citations
The roles of caspase-3 and bcl-2 in chemically-induced apoptosis but not necrosis of renal epithelial cells
1999 • 78 citations
MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells
2003 • 75 citations
The leukocyte NADPH oxidase.
2002 • 73 citations
Mitochondrial metabolism underlies hyperoxic cell damage
2004 • 72 citations
Bcl-2 protects against hyperoxia-induced apoptosis through inhibition of the mitochondria-dependent pathway☆
2007 • 72 citations
Branched fungal β‐glucan causes hyperinflammation and necrosis in phagocyte NADPH oxidase‐deficient mice
2007 • 60 citations
Inhibition of c-Jun N-Terminal Kinase Pathway Improves Cell Viability in Response to Oxidant Injury
2003 • 56 citations
Effects of Various Body Temperatures After Lipopolysaccharide-Induced Lung Injury in Rats
2005 • 56 citations
Primary Mouse Endothelial Cell Culture for Assays of Angiogenesis
2006 • 55 citations
Insulin-induced vascular endothelial growth factor expression is mediated by the NADPH oxidase NOX3
2006 • 50 citations
Mitochondrial cytochromecrelease is a key event in hyperoxia-induced lung injury: protection by cyclosporin A
2004 • 44 citations
Nonphagocytic Oxidase 1 Causes Death in Lung Epithelial Cells via a TNF-RI–JNK Signaling Axis
2006 • 32 citations
Characterization of immortalized MARCO and SR-AI/II-deficient murine alveolar macrophage cell lines
2008 • 27 citations
Response of Alveolar Macrophage-Depleted Rats to Hyperoxia
1995 • 27 citations
Granulocyte Independence of Pulmonary Oxygen Toxicity in the Rat
1989 • 23 citations
CARDIAC RELEASE OF B-TYPE NATRIURETIC PEPTIDE, CYTOKINES, AND INFLAMMATORY MARKERS IN CONGENITAL HEART DISEASE: PERIOPERATIVE SETTING UNDERGOING CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS
2005 • 23 citations
NADPH Oxidase (NOX1) Is Essential in Hyperoxia-Induced Lung Damage.
2009 • 1 citations
Cited By (0)
No citing papers found in database