Nonphagocytic Oxidase 1 Causes Death in Lung Epithelial Cells via a TNF-RI–JNK Signaling Axis

NOX enzymes and the biology of reactive oxygen

2004 • 2,940 citations

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1

1998 • 2,360 citations

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

1997 • 2,284 citations

A Direct Role for Dual Oxidase in Drosophila Gut Immunity

2005 • 751 citations

Inhibition of JNK activation through NF-κB target genes

2001 • 720 citations

Cutting Edge: Direct Interaction of TLR4 with NAD(P)H Oxidase 4 Isozyme Is Essential for Lipopolysaccharide-Induced Production of Reactive Oxygen Species and Activation of NF-κB

2004 • 609 citations

Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by Tumor Necrosis Factor Receptor-Associated Factor 2 Requires Prior Dissociation of the ASK1 Inhibitor Thioredoxin

2000 • 533 citations

NF- B inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death

2003 • 494 citations

Future Research Directions in Acute Lung Injury

2003 • 492 citations

Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense

2003 • 490 citations

Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation

2004 • 397 citations

TNF-Induced Recruitment and Activation of the IKK Complex Require Cdc37 and Hsp90

2002 • 393 citations

Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction

1998 • 351 citations

Activation of apoptosis signal‐regulating kinase 1 by the stress‐induced activating phosphorylation of pre‐formed oligomer

2002 • 349 citations

Disruption of Hsp90 Function Results in Degradation of the Death Domain Kinase, Receptor-interacting Protein (RIP), and Blockage of Tumor Necrosis Factor-induced Nuclear Factor-κB Activation

2000 • 328 citations

JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species

2004 • 294 citations

Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases

2002 • 281 citations

Tumor necrosis factor alpha -induced activation of c-jun N-terminal kinase is mediated by TRAF2

1997 • 273 citations

Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells

2005 • 249 citations

Role of Glutaredoxin in Metabolic Oxidative Stress

2002 • 248 citations

Characteristics of Patients with Asthma Within a Large HMO

1998 • 241 citations

Involvement of NADPH Oxidase Isoforms and Src Family Kinases in CD95-dependent Hepatocyte Apoptosis

2005 • 236 citations

Lung Inflammation and Fibrosis

1998 • 220 citations

Recruitment of Tumor Necrosis Factor Receptor-associated Factor Family Proteins to Apoptosis Signal-regulating Kinase 1 Signalosome Is Essential for Oxidative Stress-induced Cell Death

2005 • 214 citations

Cytokine-induced Activation of Nuclear Factor-κB Is Inhibited by Hydrogen Peroxide through Oxidative Inactivation of IκB Kinase

2001 • 189 citations

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2002 • 180 citations

Hsp90–Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis

2005 • 169 citations

Essential Roles of Receptor-Interacting Protein and TRAF2 in Oxidative Stress-Induced Cell Death

2004 • 145 citations

The Absence of NF-κB-Mediated Inhibition of c-Jun N-Terminal Kinase Activation Contributes to Tumor Necrosis Factor Alpha-Induced Apoptosis

2002 • 138 citations

NADPH Oxidase-dependent Acid Production in Airway Epithelial Cells

2004 • 135 citations

Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)

1999 • 114 citations

Toll-like receptor 4 regulates gastric pit cell responses to Helicobacter pylori infection.

2001 • 88 citations

Hydrogen Peroxide Signaling through Tumor Necrosis Factor Receptor 1 Leads to Selective Activation of c-Jun N-terminal Kinase

2003 • 81 citations

Update in Clinical Toxicology

2002 • 68 citations

TNFα Activates c-Jun Amino Terminal Kinase through p47phox

2002 • 68 citations

Nuclear Factor-κB p50 Limits Inflammation and Prevents Lung Injury duringEscherichia coliPneumonia

2003 • 65 citations

Reactive Nitrogen Species and Cell Signaling

2002 • 64 citations

Transactivation of the EGF receptor and a PI3 kinase–ATF‐1 pathway is involved in the upregulation of NOX1, a catalytic subunit of NADPH oxidase

2005 • 56 citations

Reactive Nitrogen Species-Induced Cell Death Requires Fas-Dependent Activation of c-Jun N-Terminal Kinase

2004 • 52 citations

Redox signaling.

2002 • 35 citations

Eosinophil peroxidase catalyzes JNK-mediated membrane blebbing in a Rho kinase-dependent manner

2003 • 19 citations