Immunosenescent colitogenic CD4⁺ T cells convert to regulatory cells and suppress colitis

An obesity-associated gut microbiome with increased capacity for energy harvest

2006 • 11,120 citations

Restoring function in exhausted CD8 T cells during chronic viral infection

2005 • 3,743 citations

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

1998 • 3,085 citations

Inflammatory Bowel Disease

2002 • 3,038 citations

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

2005 • 2,667 citations

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

2006 • 2,521 citations

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 • 1,995 citations

Inflammatory bowel disease: cause and immunobiology

2007 • 1,916 citations

The immunological and genetic basis of inflammatory bowel disease

2003 • 1,766 citations

The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection

2007 • 1,416 citations

Anatomical basis of tolerance and immunity to intestinal antigens

2003 • 1,365 citations

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation–mediated apoptosis of effector CD4+ T cells

2007 • 1,161 citations

Similarities and differences in CD4+ and CD8+ effector and memory T cell generation

2003 • 865 citations

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

2001 • 600 citations

Finding a way out: lymphocyte egress from lymphoid organs

2007 • 573 citations

Inflammatory Bowel Disease

1991 • 562 citations

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

2006 • 474 citations

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

2003 • 454 citations

T cells and viral persistence: lessons from diverse infections

2005 • 407 citations

Host-reactive CD8+ memory stem cells in graft-versus-host disease

2005 • 348 citations

Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE

2006 • 291 citations

Homeostasis of memory T cells

2006 • 275 citations

IL-7: maintaining T-cell memory and achieving homeostasis

2005 • 232 citations

New Concepts in the Pathophysiology of Inflammatory Bowel Disease

2005 • 217 citations

The role of models in understanding CD8+ T-cell memory

2005 • 211 citations

Why Aging T Cells Fail: Implications for Vaccination

2006 • 164 citations

Novel pathophysiological concepts of inflammatory bowel disease

2006 • 162 citations

Intestinal Lamina Propria Retaining CD4+CD25+ Regulatory T Cells Is A Suppressive Site of Intestinal Inflammation

2007 • 101 citations

Significance of senescence for virus-specific memory T cell responses: rapid ageing during chronic stimulation of the immune system

2004 • 94 citations

Immunity and age: living in the past?

2006 • 88 citations

IL-7 Is Essential for the Development and the Persistence of Chronic Colitis

2007 • 72 citations

Ameliorating effect of anti-inducible costimulator monoclonal antibody in a murine model of chronic colitis

2003 • 69 citations

Control of Experimental Inflammatory Bowel Disease by Regulatory T cells

2000 • 63 citations

Bone Marrow Retaining Colitogenic CD4+ T Cells May Be a Pathogenic Reservoir for Chronic Colitis

2006 • 54 citations

Regulation of murine chronic colitis by CD4+CD25- programmed death-1+ T cells

2005 • 49 citations

4 The natural history of ulcerative colitis

1997 • 46 citations

Not all CD4⁺ memory T cells are long lived

2006 • 42 citations

Naturally arising CD4⁺CD25⁺ regulatory T cells suppress the expansion of colitogenic CD4⁺CD44^highCD62L⁻ effector memory T cells

2005 • 18 citations

In Vivo Generation of Oligoclonal Colitic CD4+ T-Cell Lines Expressing a Distinct T-Cell Receptor Vβ

2005 • 5 citations