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Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

Data up to Jan 2025

Published1999
Citations521
References56

Total Citations Per Year

Abstract

References (56)

Wound Healing--Aiming for Perfect Skin Regeneration

1997 • 4,630 citations

STATs and Gene Regulation

1997 • 3,927 citations

Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation

1983 • 2,745 citations

Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis

1990 • 2,262 citations

Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6

1994 • 2,037 citations

TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway

1995 • 1,826 citations

Essential role of Stat6 in IL-4 signalling

1996 • 1,563 citations

Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease

1996 • 1,560 citations

STATs: Signal Transducers and Activators of Transcription

1996 • 1,414 citations

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

1997 • 1,306 citations

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1996 • 1,277 citations

Enhanced Th1 Activity and Development of Chronic Enterocolitis in Mice Devoid of Stat3 in Macrophages and Neutrophils

1999 • 1,228 citations

A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

1991 • 1,135 citations

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1997 • 1,106 citations

De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin

1998 • 1,082 citations

Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes

1977 • 1,063 citations

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

1995 • 1,035 citations

Strain-Dependent Epithelial Defects in Mice Lacking the EGF Receptor

1995 • 1,016 citations

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

1997 • 989 citations

The secret life of the hair follicle

1992 • 919 citations

Production and auto-induction of transforming growth factor-α in human keratinocytes

1987 • 870 citations

Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes.

1989 • 844 citations

Sonic hedgehog signaling is essential for hair development

1998 • 742 citations

Cell migration is essential for sustained growth of keratinocyte colonies: The roles of transforming growth factor-α and epidermal growth factor

1987 • 703 citations

TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice

1993 • 659 citations

Growth factors and wound healing: Biochemical properties of growth factors and their receptors

1993 • 650 citations

The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix

1997 • 600 citations

The Function of KGF in Morphogenesis of Epithelium and Reepithelialization of Wounds

1994 • 597 citations

Requirement of Serine Phosphorylation for Formation of STAT-Promoter Complexes

1995 • 578 citations

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

1998 • 513 citations

Conditional gene targeting.

1996 • 462 citations

Jaks, STATs, Cytokine Signal Transduction, and Immunoregulation: Are We There Yet?

1997 • 381 citations

Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation

1997 • 348 citations

Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development

1997 • 263 citations

Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure.

1995 • 247 citations

IL-6-regulated transcription factors

1997 • 236 citations

Epidermal growth factor (EGF)- and scatter factor/hepatocyte growth factor (SF/HGF)-mediated keratinocyte migration is coincident with induction of matrix metalloproteinase (MMP)-9

1998 • 220 citations

Marked stimulation of growth and motility of human keratinocytes by hepatocyte growth factor

1991 • 217 citations

Sequences 5′ of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development

1994 • 208 citations

Separation of the epidermal sheet by dispase

1983 • 187 citations

Transgenic mice as a model to study the role of TGF-beta-related molecules in hair follicles.

1993 • 170 citations

Epidermal Growth Factor (EGF) Promotes Human Keratinocyte Locomotion on Collagen by Increasing the α2 Integrin Subunit

1993 • 162 citations

HAIR FOLLICLE GROWTH CONTROLS

1996 • 152 citations

Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles

1994 • 139 citations

Probing Keratinocyte and Differentiation Specificity of the Human K5 Promoter in Vitro and in Transgenic Mice

1993 • 134 citations

Outer root sheath cells of human hair follicle are able to regenerate a fully differentiated epidermis in vitro

1988 • 117 citations

Distribution of Epidermal Growth Factor Receptors in Rat Tissues During Embryonic Skin Development, Hair Formation, and the Adult Hair Growth Cycle

1984 • 113 citations

Mechanisms of Hepatocyte Growth Factor Stimulation of Keratinocyte Metalloproteinase Production

1996 • 109 citations

GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE

1996 • 106 citations

Interleukin 6 promotes epithelial migration by a fibronectin‐dependent mechanism

1992 • 94 citations

Local Injection of Hepatocyte Growth Factor/Scatter Factor (HGF/SF) Alters Cyclic Growth of Murine Hair Follicles

1998 • 84 citations

EFFECTS OF EPIDERMAL GROWTH FACTOR ON HAIR GROWTH IN THE MOUSE

1981 • 83 citations

Comparative Study of Hepatocyte Growth Factor/Scatter Factor and Keratinocyte Growth Factor Effects on Human Keratinocytes

1995 • 80 citations

Specific Inhibition of Hair Follicle Formation by Epidermal Growth Factor in an Organ Culture of Developing Mouse Skin

1997 • 51 citations

Regulation of Hair Follicle Development: An In Vitro Model for Hair Follicle Invasion of Dermis and Associated Connective Tissue Remodeling.

1993 • 31 citations

Deleted Work

1955 • 0 citations

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Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not… (1999) – The EMBO Journal | Metascience Observatory Explorer