Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway

1996 • 1,648 citations

Essential role of Stat6 in IL-4 signalling

1996 • 1,563 citations

Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease

1996 • 1,560 citations

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

1996 • 1,304 citations

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1996 • 1,277 citations

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1996 • 1,182 citations

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1997 • 1,106 citations

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

1995 • 641 citations

Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.

1994 • 599 citations

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.

1995 • 556 citations

Mode of Action of Pituitary Growth Hormone on Target Cells

1985 • 452 citations

marelle Acts Downstream of the Drosophila HOP/JAK Kinase and Encodes a Protein Similar to the Mammalian STATs

1996 • 375 citations

Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity.

1995 • 374 citations

Interleukin-3 signals through multiple isoforms of Stat5.

1995 • 327 citations

Molecular Mechanism of Growth Hormone Action

1996 • 309 citations

Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450.

1991 • 255 citations

Growth hormone and the adipose conversion of 3T3 cells

1982 • 254 citations

Intermittent Plasma Growth Hormone Triggers Tyrosine Phosphorylation and Nuclear Translocation of a Liver-Expressed, Stat 5-related DNA Binding Protein.

1995 • 242 citations

The Growth Hormone/Prolactin Receptor Family

1993 • 227 citations

Secretory rhythm of growth hormone regulates sexual differentiation of mouse liver

1984 • 226 citations

Growth Hormone Activation of Stat 1, Stat 3, and Stat 5 in Rat Liver

1996 • 225 citations

Identification and purification of human stat proteins activated in response to interleukin-2

1995 • 223 citations

The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

1996 • 198 citations

Distribution of the Mammalian Stat Gene Family in Mouse Chromosomes

1995 • 195 citations

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.

1995 • 190 citations

Transcription Factors Stat3 and Stat5b Are Present in Rat Liver Nuclei Late in an Acute Phase Response and Bind Interleukin-6 Response Elements

1995 • 174 citations

Sex differences in the ultradian pattern of plasma growth hormone concentrations in mice

1991 • 165 citations

Epidermal growth factor induces the tyrosine phosphorylation and nuclear translocation of Stat 5 in mouse liver.

1995 • 139 citations

Mammary gland-specific nuclear factor is present in lactating rodent and bovine mammary tissue and composed of a single polypeptide of 89 kDa.

1992 • 137 citations

Regulation of Signal Transducer and Activator of Transcription (STAT) 5b Activation by the Temporal Pattern of Growth Hormone Stimulation

1997 • 129 citations

Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and STAT91.

1994 • 123 citations

Sex-specific, growth hormone-regulated transcription of the cytochrome P450 2C11 and 2C12 genes.

1992 • 115 citations

In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3.

1995 • 106 citations

Growth induced by pulsatile infusion of an amidated fragment of human growth hormone releasing factor in normal and GHRF-deficient rats

1985 • 95 citations

Pretranslational regulation of sex-dependent testosterone hydroxylases by growth hormone in mouse liver.

1986 • 89 citations

Regulation of liver-specific steroid metabolizing cytochromes P450: Cholesterol 7α-hydroxylase, bile acid 6β-hydroxylase, and growth hormone-responsive steroid hormone hydroxylases

1992 • 83 citations

STAT3 and STAT5B Are Targets of Two Different Signal Pathways Activated by Hematopoietin Receptors and Control Transcription via Separate Cytokine Response Elements

1995 • 76 citations

Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.

1996 • 67 citations

A STAT Factor Mediates the Sexually Dimorphic Regulation of Hepatic Cytochrome P450 3A10/Lithocholic Acid 6β-Hydroxylase Gene Expression by Growth Hormone

1995 • 65 citations

Prolactin induction of the alpha 2-Macroglobulin gene in rat ovarian granulosa cells: stat 5 activation and binding to the interleukin-6 response element.

1996 • 62 citations

[44] P450-catalyzed steroid hydroxylation: Assay and product identification by thin-layer chromatography

1991 • 60 citations

Developmental and hormonal regulation of alpha 2u-globulin gene transcription.

1985 • 59 citations

Monoclonal antibodies inhibitory to rat hepatic cytochromes P-450: P-450 form specificities and use as probes for cytochrome P-450-dependent steroid hydroxylations.

1987 • 56 citations

Interaction of a Novel Sex-dependent, Growth Hormone-regulated Liver Nuclear Factor with CYP2C12 Promoter

1996 • 48 citations

Laron syndrome due to a post-receptor defect: response to IGF-I treatment.

1993 • 46 citations

Renaturalizing the sexually dimorphic profiles of circulating growth hormone in hypophysectomized rats

1991 • 35 citations

Differential regulation of plasma levels of insulin-like growth factors-I and -II by nutrition, age and growth hormone treatment in sheep

1995 • 34 citations

The activated mammary gland specific nuclear factor (MGF) enhances in vitro transcription of the β-casein gene promoter

1993 • 26 citations

The role and mechanism of growth hormone in the regulation of sexually dimorphic P450 enzymes in rat liver

1992 • 22 citations

Microplate DNA preparation, PCR screening and cell freezing for gene targeting in embryonic stem cells.

1994 • 16 citations

Disorders of growth hormone resistance in childhood

1993 • 15 citations

[25] Expression of genes within mouse IIA and IID subfamilies: Simultaneous measurement of homologous P450 mRNAs

1991 • 8 citations

[Growth hormone receptor and dwarfism].

1994 • 3 citations