The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

1988 • 4,008 citations

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

1994 • 2,497 citations

Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage.

1996 • 940 citations

Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas

1994 • 769 citations

92-kD type IV collagenase mediates invasion of human cytotrophoblasts.

1991 • 722 citations

Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice.

1996 • 496 citations

The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis.

1996 • 491 citations

The phagokinetic tracks of 3T3 cells

1977 • 434 citations

The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen.

1989 • 422 citations

Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases.

1990 • 406 citations

Expression of integrins and basement membrane components by wound keratinocytes.

1993 • 402 citations

Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing.

1993 • 319 citations

A targeted mutation at the known collagenase cleavage site in mouse type I collagen impairs tissue remodeling.

1995 • 280 citations

Laminin-5 Inhibits Human Keratinocyte Migration

1997 • 263 citations

Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis.

1992 • 253 citations

Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds.

1994 • 238 citations

Interstitial Collagenase Is Required for Angiogenesis in Vitro

1994 • 231 citations

Regulation of extracellular matrix proteins and integrin cell substratum adhesion receptors on epithelium during cutaneous human wound healing in vivo.

1993 • 224 citations

Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion.

1993 • 210 citations

Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis.

1986 • 206 citations

Integrin expression during human epidermal development in vivo and in vitro

1991 • 203 citations

Distinctive Integrin Expression in the Newly Forming Epidermis During Wound Healing in Humans

1993 • 200 citations

Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization.

1989 • 193 citations

Laminin 5 Deposition Promotes Keratinocyte Motility

1996 • 185 citations

Fate of human keratinocytes during reepithelialization in an organotypic culture model.

1994 • 169 citations

Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma.

1992 • 167 citations

Chondrocyte matrix metalloproteinase-8: up-regulation of neutrophil collagenase by interleukin-1 beta in human cartilage from knee and ankle joints.

1996 • 151 citations

Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes.

1995 • 150 citations

Collagenase Expression Is Rapidly Induced in Wound-Edge Keratinocytes After Acute Injury in Human Skin, Persists During Healing, and Stops at Re-Epithelialization

1995 • 136 citations

Generation of collagenase-resistant collagen by site-directed mutagenesis of murine pro alpha 1(I) collagen gene.

1990 • 121 citations

Purification of human collagenases with a hydroxamic acid affinity column

1986 • 114 citations

Cell type-specific regulation of SL-1 and SL-2 genes. Induction of the SL-2 gene but not the SL-1 gene by human keratinocytes in response to cytokines and phorbolesters

1993 • 97 citations

Differential in vivo expression of collagenase messenger RNA in synovium and cartilage. Quantitative comparison with stromelysin messenger rna levels in human rheumatoid arthritis and osteoarthritis patients and in two animal models of acute inflammatory arthritis

1993 • 96 citations

Localization of mRNAs representing collagenase and TIMP in sections of healing human burn wounds.

1993 • 95 citations

Collagen-stimulated induction of keratinocyte collagenase is mediated via tyrosine kinase and protein kinase C activities.

1994 • 94 citations

Vitronectin-driven human keratinocyte locomotion is mediated by the alpha v beta 5 integrin receptor.

1994 • 86 citations

Distinct mechanisms regulate interstitial collagenase and 92-kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin

1993 • 86 citations

Interstitial Collagenase Is Expressed by Keratinocytes That Are Actively Involved in Reepithelialization in Blistering Skin Diseases

1995 • 81 citations

Mg2+ and Ca2+ Differentially Regulate β1 Integrin-Mediated Adhesion of Dermal Fibroblasts and Keratinocytes to Various Extracellular Matrix Proteins

1994 • 74 citations

Proteinases and Tissue Remodeling

1988 • 65 citations

Altered processing of integrin receptors during keratinocyte activation*1

1991 • 63 citations

Modulation of intracellular calcium levels inhibits secretion of collagenase 1 by migrating keratinocytes.

1997 • 37 citations