Integrative analysis of the cancer transcriptome

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Molecular portraits of human breast tumours

2000 • 15,445 citations

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

1999 • 11,586 citations

In silico prediction of protein-protein interactions in human macrophages

2014 • 11,120 citations

Significance analysis of microarrays applied to the ionizing radiation response

2001 • 10,393 citations

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

2000 • 9,712 citations

Statistical significance for genomewide studies

2003 • 9,411 citations

Gene expression profiling predicts clinical outcome of breast cancer

2002 • 9,314 citations

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

2003 • 8,996 citations

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

2002 • 6,428 citations

Repeated observation of breast tumor subtypes in independent gene expression data sets

2003 • 5,356 citations

The KEGG resource for deciphering the genome

2003 • 4,678 citations

The Gene Ontology (GO) database and informatics resource

2003 • 4,254 citations

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

2001 • 4,058 citations

ONCOMINE: A Cancer Microarray Database and Integrated Data-Mining Platform

2004 • 3,585 citations

A census of human cancer genes

2004 • 3,190 citations

A molecular signature of metastasis in primary solid tumors

2002 • 2,424 citations

TRANSFAC(R): transcriptional regulation, from patterns to profiles

2003 • 2,010 citations

Prediction of Survival in Follicular Lymphoma Based on Molecular Features of Tumor-Infiltrating Immune Cells

2004 • 1,395 citations

Control of Pancreas and Liver Gene Expression by HNF Transcription Factors

2004 • 1,293 citations

GoMiner: a resource for biological interpretation of genomic and proteomic data

2003 • 1,211 citations

NCBI GEO: mining millions of expression profiles--database and tools

2004 • 1,138 citations

Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans

2003 • 1,114 citations

ArrayExpress--a public repository for microarray gene expression data at the EBI

2004 • 1,104 citations

FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes

2004 • 1,098 citations

Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression

2004 • 1,025 citations

Prediction of cancer outcome with microarrays: a multiple random validation strategy

2005 • 982 citations

MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data

2003 • 865 citations

Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

2004 • 799 citations

A module map showing conditional activity of expression modules in cancer

2004 • 693 citations

WormBase: a multi-species resource for nematode biology and genomics

2003 • 673 citations

Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer.

2002 • 656 citations

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

2003 • 524 citations

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

2002 • 449 citations

A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer

2003 • 421 citations

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis

2004 • 420 citations

From signatures to models: understanding cancer using microarrays

2005 • 383 citations

Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate

2003 • 356 citations

Genome-Wide In Silico Identification of Transcriptional Regulators Controlling the Cell Cycle in Human Cells

2003 • 304 citations

Joint analysis of two microarray gene-expression data sets to select lung adenocarcinoma marker genes

2004 • 285 citations

Gene expression phenotypic models that predict the activity of oncogenic pathways

2003 • 264 citations

Mining for regulatory programs in the cancer transcriptome

2005 • 170 citations

Prognostic meta-signature of breast cancer developed by two-stage mixture modeling of microarray data

2004 • 126 citations

GOAL: automated Gene Ontology analysis of expression profiles

2004 • 43 citations