Genome-Wide In Silico Identification of Transcriptional Regulators Controlling the Cell Cycle in Human Cells

Gene Ontology: tool for the unification of biology

2000 • 38,297 citations

Systematic determination of genetic network architecture

1999 • 2,535 citations

Genomics, gene expression and DNA arrays

2000 • 2,039 citations

Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors

2002 • 1,465 citations

TRANSFAC: an integrated system for gene expression regulation

2000 • 1,236 citations

E2F integrates cell cycle progression with DNA repair, replication, and G₂/M checkpoints

2002 • 1,102 citations

Computational identification of Cis -regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae 1 1Edited by F. E. Cohen

2000 • 1,031 citations

The Rb/E2F pathway and cancer

2001 • 913 citations

Identifying regulatory networks by combinatorial analysis of promoter elements

2001 • 652 citations

Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome

2002 • 619 citations

Role for E2F in Control of Both DNA Replication and Mitotic Functions as Revealed from DNA Microarray Analysis

2001 • 587 citations

A survey of 178 NF-Y binding CCAAT boxes

1998 • 521 citations

NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells.

1990 • 404 citations

Identification of regulatory regions which confer muscle-specific gene expression

1998 • 401 citations

Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo

2001 • 378 citations

Regulatory Networks Revealed by Transcriptional Profiling of DamagedSaccharomyces cerevisiaeCells: Rpn4 Links Base Excision Repair with Proteasomes

2000 • 336 citations

Computation-Based Discovery of Related Transcriptional Regulatory Modules and Motifs Using an Experimentally Validated Combinatorial Model

2002 • 316 citations

Aromatic Hydrocarbon Receptor Interaction with the Retinoblastoma Protein Potentiates Repression of E2F-dependent Transcription and Cell Cycle Arrest

2000 • 306 citations

E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

2002 • 263 citations

Sequential Serum-dependent Activation of CREB and NRF-1 Leads to Enhanced Mitochondrial Respiration through the Induction of Cytochrome c

2000 • 184 citations

Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors

2001 • 178 citations

NCBI's LocusLink and RefSeq

2000 • 171 citations

NF-Y Mediates the Transcriptional Inhibition of thecyclin B1, cyclin B2, and cdc25CPromoters upon Induced G2 Arrest

2001 • 169 citations

Complementation of Ah Receptor Deficiency in Hepatoma Cells: Negative Feedback Regulation and Cell Cycle Control by the Ah Receptor

1996 • 167 citations

Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1

2002 • 166 citations

p53 Negatively Regulates cdc2 Transcription via the CCAAT-binding NF-Y Transcription Factor

1999 • 159 citations

Journey to the Center of Biology

2000 • 145 citations

cAMP Response Element-binding Protein Content Is a Molecular Determinant of Smooth Muscle Cell Proliferation and Migration

2001 • 140 citations

Recognition of NFATp/AP-1 composite elements within genes induced upon the activation of immune cells

1999 • 128 citations

Maximal Aryl Hydrocarbon Receptor Activity Depends on an Interaction with the Retinoblastoma Protein

2001 • 126 citations

Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription

2001 • 120 citations

The Eukaryotic Promoter Database, EPD: new entry types and links to gene expression data

2002 • 117 citations

Indole-3-carbinol Inhibits CDK6 Expression in Human MCF-7 Breast Cancer Cells by Disrupting Sp1 Transcription Factor Interactions with a Composite Element in the CDK6 Gene Promoter

2001 • 114 citations

Stat5 and Sp1 Regulate Transcription of the Cyclin D2 Gene in Response to IL-2

2001 • 112 citations

Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter 1 1Edited by M. Yaniv

1999 • 98 citations

p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor

2001 • 93 citations

Interaction between YY1 and the Retinoblastoma Protein

2001 • 85 citations

Cooperation of E2F-p130 and Sp1-pRb Complexes in Repression of the Chinese Hamster dhfr Gene

2001 • 64 citations

E2F-mediated Growth Regulation Requires Transcription Factor Cooperation

1997 • 64 citations

Nuclear Factor Y (NF-Y) and Cellular Senescence

1999 • 63 citations

Transcriptional Regulation of the Human Tumor Suppressor p14ARF by E2F1, E2F2, E2F3, and Sp1-like Factors

2002 • 55 citations

Muscle actin genes: a first step towards computational classification of tissue specific promoters.

1998 • 49 citations

YY1 as a Regulator of Replication-dependent Hamster Histone H3.2 Promoter and an Interactive Partner of AP-2

2001 • 47 citations

Two YY-1-binding Proximal Elements Regulate the Promoter Strength of the TATA-less Mouse Ribonucleotide Reductase R1 Gene

1998 • 44 citations

Molecular cloning and sequence analysis of the promoter region of mouse cyclin D1 gene: implication in phorbol ester‐induced tumour promotion

2000 • 42 citations

Cell-cycle-regulated phosphorylation of cAMP response element-binding protein: identification of novel phosphorylation sites

1999 • 35 citations

Cyclin A Down-Regulation in TGFβ1-Arrested Follicular Lymphoma Cells

2000 • 23 citations

E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase varepsilon B-subunit gene POLE2

2001 • 21 citations

The transcription factor ATF-2 inhibits extracellular signal regulated kinase expression and proliferation of human cancer cells.

2000 • 18 citations

E2F regulates growth‐dependent transcription of genes encoding both catalytic and regulatory subunits of mouse primase

2001 • 11 citations

Structure and promoter activity of the mouse CDC25A gene

2000 • 10 citations