A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer

Molecular portraits of human breast tumours

2000 • 15,445 citations

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

1999 • 11,586 citations

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

2000 • 9,712 citations

Gene expression profiling predicts clinical outcome of breast cancer

2002 • 9,314 citations

CDK inhibitors: positive and negative regulators of G1-phase progression

1999 • 6,003 citations

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

A simplified system for generating recombinant adenoviruses

1998 • 3,179 citations

G1 phase progression: Cycling on cue

1994 • 2,706 citations

Functional Discovery via a Compendium of Expression Profiles

2000 • 2,581 citations

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

2001 • 2,560 citations

Gene expression correlates of clinical prostate cancer behavior

2002 • 2,504 citations

Prediction of central nervous system embryonal tumour outcome based on gene expression

2002 • 2,359 citations

The regulation of E2F by pRB-family proteins

1998 • 2,297 citations

Multiclass cancer diagnosis using tumor gene expression signatures

2001 • 2,021 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

Biological Role of the CCAAT/Enhancer-binding Protein Family of Transcription Factors

1998 • 799 citations

Genetic Alterations of Cyclins, Cyclin-Dependent Kinases, and Cdk Inhibitors in Human Cancer

1996 • 751 citations

CDK-Independent Activation of Estrogen Receptor by Cyclin D1

1997 • 698 citations

Molecular classification of human carcinomas by use of gene expression signatures.

2001 • 681 citations

Chemosensitivity prediction by transcriptional profiling

2001 • 673 citations

Role for E2F in Control of Both DNA Replication and Mitotic Functions as Revealed from DNA Microarray Analysis

2001 • 587 citations

Function of a human cyclin gene as an oncogene.

1994 • 471 citations

PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma.

1991 • 454 citations

Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice.

1995 • 418 citations

Cyclin D1 Stimulation of Estrogen Receptor Transcriptional Activity Independent of cdk4†

1997 • 386 citations

Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions

1995 • 334 citations

D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability.

1999 • 187 citations

Gene Expression and Cell Cycle Arrest Mediated by Transcription Factor DMP1 Is Antagonized by D-Type Cyclins through a Cyclin-Dependent-Kinase-Independent Mechanism

1998 • 165 citations

Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene.

1994 • 156 citations

Overexpression of C/EBP -LIP, a Naturally Occurring, Dominant-Negative Transcription Factor, in Human Breast Cancer

1997 • 137 citations

Developmentally and hormonally regulated CCAAT/enhancer-binding protein isoforms influence beta-casein gene expression.

1995 • 128 citations

Cyclin D1 (PRAD1) protein expression in breast cancer: approximately one-third of infiltrating mammary carcinomas show overexpression of the cyclin D1 oncogene.

1995 • 127 citations

Cyclin D1 Represses STAT3 Activation through a Cdk4-independent Mechanism

2001 • 115 citations

Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2alpha are correlated with neoplastic transformation of mammary epithelial cells.

1996 • 112 citations

Development of mammary preneoplasias in vivo from mouse mammary epithelial cell lines in vitro.

1992 • 111 citations

Frequent overexpression of the cyclin D1 oncogene in invasive lobular carcinoma of the breast.

1998 • 101 citations

A role for CCAAT/enhancer binding protein beta-liver-enriched inhibitory protein in mammary epithelial cell proliferation.

2001 • 98 citations

Regulation of the Functional Interaction between Cyclin D1 and the Estrogen Receptor

2000 • 90 citations

Cyclin D1 Represses the Basic Helix-Loop-Helix Transcription Factor, BETA2/NeuroD

2002 • 81 citations

CCAAT/Enhancer-binding Protein-β Is a Mediator of the Nutrient-sensing Response Pathway That Activates the Human Asparagine Synthetase Gene

2001 • 79 citations

Cyclin D1 gene amplification and overexpression are present in ductal carcinomain situ of the breast

1999 • 61 citations

Expression of the retinoblastoma protein in low-grade B-cell lymphoma: relationship to cyclin D1

1996 • 57 citations

A novel transiently expressed, integral membrane protein linked to cell activation. Molecular cloning via the rapid degradation signal AUUUA.

1992 • 56 citations

CHOP/GADD153 and Methionyl-tRNA Synthetase (MetRS) Genes Overlap in a Conserved Region That Controls mRNA Stability

1999 • 30 citations

B-Myb and cyclin D1 mediate heat shock element dependent activation of the human HSP70 promoter

1997 • 30 citations