Gene expression phenotypic models that predict the activity of oncogenic pathways

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

1999 • 11,586 citations

Gene expression profiling predicts clinical outcome of breast cancer

2002 • 9,314 citations

Stat3 as an Oncogene

1999 • 2,770 citations

Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

2002 • 2,400 citations

Prediction of central nervous system embryonal tumour outcome based on gene expression

2002 • 2,359 citations

The regulation of E2F by pRB-family proteins

1998 • 2,297 citations

Predicting the clinical status of human breast cancer by using gene expression profiles

2001 • 1,336 citations

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

2000 • 830 citations

Distinct roles for E2F proteins in cell growth control and apoptosis

1997 • 694 citations

Toward an understanding of the functional complexity of the E2F and retinoblastoma families.

1998 • 524 citations

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

2001 • 408 citations

Cyclin D1 Is Required for Transformation by Activated Neu and Is Induced through an E2F-Dependent Signaling Pathway

2000 • 346 citations

Functional analysis of E2F transcription factor

1997 • 85 citations

Differential effects of p21(WAF1/CIP1) deficiency on MMTV-ras and MMTV-myc mammary tumor properties.

2002 • 62 citations