Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

Genome-Wide Location and Function of DNA Binding Proteins

2000 • 1,720 citations

Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF

2001 • 1,101 citations

Number of CpG islands and genes in human and mouse.

1993 • 986 citations

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1993 • 960 citations

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G₁/S-Regulatory Genes

1995 • 910 citations

Rb targets histone H3 methylation and HP1 to promoters

2001 • 892 citations

p53 and E2F-1 cooperate to mediate apoptosis.

1994 • 844 citations

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.

1994 • 772 citations

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis

2001 • 747 citations

Promoter-specific binding of Rap1 revealed by genome-wide maps of protein–DNA association

2001 • 707 citations

Role for E2F in Control of Both DNA Replication and Mitotic Functions as Revealed from DNA Microarray Analysis

2001 • 587 citations

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis.

1994 • 515 citations

Purification of CpG islands using a methylated DNA binding column

1994 • 449 citations

Methylation profiling of CpG islands in human breast cancer cells

1999 • 434 citations

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis

1995 • 422 citations

Use of Chromatin Immunoprecipitation To Clone Novel E2F Target Promoters

2001 • 387 citations

An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription.

1993 • 342 citations

Large-scale human promoter mapping using CpG islands

2000 • 302 citations

Dissecting complex epigenetic alterations in breast cancer using CpG island microarrays.

2001 • 241 citations

Mre11 Complex and DNA Replication: Linkage to E2F and Sites of DNA Synthesis

2001 • 214 citations

Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors

2001 • 178 citations

Deregulated Expression of E2F-1 Induces S-Phase Entry and Leads to Apoptosis

1994 • 160 citations

Promoter prediction in the human genome

2001 • 125 citations

The transcription factor E2F-1 mediates the autoregulation of RB gene expression

1994 • 122 citations

Oligosaccharide signals: from plant defense to parasite offense.

1994 • 72 citations

Thymidylate synthase expression correlates closely with E2F1 expression in colon cancer.

2000 • 66 citations

The E2F Transcription Factor Activates a Replication-Dependent Human H2A Gene in Early S Phase of the Cell Cycle

1996 • 54 citations

Identification of Target Genes of Oncogenic Transcription Factors

1999 • 42 citations

Exogenous E2F expression is growth inhibitory before, during, and after cellular transformation

2000 • 25 citations